Fanyi Yang, Jianfeng Liu, Xin Zhang et al.
Instruction tuning has empowered large language models (LLMs) to achieve remarkable performance, yet its success heavily depends on the availability of large-scale, high-quality instruction-response pairs. To meet this demand, various methods have been developed to synthesize data at scale. However, current methods for scaling up data generation often overlook a crucial aspect: the alignment between instructions and responses. We hypothesize that the quality of instruction-response pairs is determined not by the individual quality of each component, but by the degree of mutual alignment. To address this, we propose a Mutual Alignment Framework (MAIN) which enforces coherence between instructions and responses through mutual constraints. We demonstrate that MAIN generalizes well across model architectures and sizes, achieving state-of-the-art performance on LLaMA, Mistral, and Qwen models across diverse benchmarks. This work underscores the critical role of instruction-response alignment in enabling generalizable and high-quality instruction tuning for LLMs. All code is available from our repository.