Otávio Parraga

Christian Mattjie, Luis Vinicius de Moura, Rafaela Cappelari Ravazio et al.

Segmentation in medical imaging is a critical component for the diagnosis, monitoring, and treatment of various diseases and medical conditions. Presently, the medical segmentation landscape is dominated by numerous specialized deep learning models, each fine-tuned for specific segmentation tasks and image modalities. The recently-introduced Segment Anything Model (SAM) employs the ViT neural architecture and harnesses a massive training dataset to segment nearly any object; however, its suitability to the medical domain has not yet been investigated. In this study, we explore the zero-shot performance of SAM in medical imaging by implementing eight distinct prompt strategies across six datasets from four imaging modalities, including X-ray, ultrasound, dermatoscopy, and colonoscopy. Our findings reveal that SAM's zero-shot performance is not only comparable to, but in certain cases, surpasses the current state-of-the-art. Based on these results, we propose practical guidelines that require minimal interaction while consistently yielding robust outcomes across all assessed contexts. The source code, along with a demonstration of the recommended guidelines, can be accessed at https://github.com/Malta-Lab/SAM-zero-shot-in-Medical-Imaging.

Otávio Parraga, Martin D. More, Christian M. Oliveira et al.

Despite being responsible for state-of-the-art results in several computer vision and natural language processing tasks, neural networks have faced harsh criticism due to some of their current shortcomings. One of them is that neural networks are correlation machines prone to model biases within the data instead of focusing on actual useful causal relationships. This problem is particularly serious in application domains affected by aspects such as race, gender, and age. To prevent models from incurring on unfair decision-making, the AI community has concentrated efforts in correcting algorithmic biases, giving rise to the research area now widely known as fairness in AI. In this survey paper, we provide an in-depth overview of the main debiasing methods for fairness-aware neural networks in the context of vision and language research. We propose a novel taxonomy to better organize the literature on debiasing methods for fairness, and we discuss the current challenges, trends, and important future work directions for the interested researcher and practitioner.

Vinícius Conte Turani, Otávio Parraga, João Vitor Boer Abitante et al.

Large Language Models memorize vast amounts of training data, raising concerns regarding privacy, copyright infringement, and safety. Machine unlearning seeks to remove the influence of a targeted forget set while preserving model performance, ideally approximating a model retrained from scratch without the forget set. Existing approaches aim to achieve this by updating model parameters via gradient-based methods. However, these updates are computationally expensive, lead to irreversible weight changes, and degrade when the model is quantized for deployment. A recent alternative to changing model weights is activation engineering, where activations are changed during inference to steer model behavior. Despite circumventing weight editing, naive activation steering introduces its own failure modes, as a single global steering vector applies the same intervention to every input, leading to unintended changes in model behavior. We introduce Inference-Time Unlearning via Gated Activation Redirection (GUARD-IT), a training- and gradient-free method that unlearns via input-dependent activation steering at inference time. The resulting intervention is applied as a norm-preserving rotation in the residual stream, leaving model weights untouched. Experiments on TOFU and MUSE show that GUARD-IT matches or exceeds 12 gradient-based baselines across three model scales, while being the only method to simultaneously preserve utility, suppress memorization, and avoid catastrophic collapse across all settings. GUARD-IT further supports continual unlearning without retraining, and remains effective under quantization, a scenario in which parameter-editing methods degrade.

Joana Pasquali, Ramiro N. Barros, Arthur S. Bianchessi et al.

LoRA is widely adopted for continual fine-tuning of Large Language Models due to its parameter efficiency, modularity across tasks, and compatibility with replay strategies. However, LoRA-based continual learning remains vulnerable to catastrophic forgetting, whose severity depends on how successive task gradients interact: when consecutive task gradients conflict, standard adapter initializations channel updates into subspaces that overwrite previously learned directions. We propose SLICE, a gradient-surgery-based initialization for LoRA adapters in continual learning. SLICE accumulates gradients from both the current task and a replay buffer of prior tasks, reconciles them through a projection operator, and decomposes the result via truncated SVD to initialize the adapter weights. We evaluate SLICE on the TRACE benchmark and sequences of Super-NI tasks, including a set of adversarial Super-NI sequences that we construct by mining task pairs with maximally opposing gradients. Compared to vanilla LoRA, LoRA-GA, and LoRAM, SLICE consistently achieves a better stability-plasticity trade-off, improving Average Performance, Final Performance and Forgetting metrics while preserving General Performance and In Context Performance across both standard and adversarial continual learning sequences.

Lucas S. Kupssinskü, Marco N. Bochernitsan, Jordan Kopper et al.

We propose DeCoDi, a debiasing procedure for text-to-image diffusion-based models that changes the inference procedure, does not significantly change image quality, has negligible compute overhead, and can be applied in any diffusion-based image generation model. DeCoDi changes the diffusion process to avoid latent dimension regions of biased concepts. While most deep learning debiasing methods require complex or compute-intensive interventions, our method is designed to change only the inference procedure. Therefore, it is more accessible to a wide range of practitioners. We show the effectiveness of the method by debiasing for gender, ethnicity, and age for the concepts of nurse, firefighter, and CEO. Two distinct human evaluators manually inspect 1,200 generated images. Their evaluation results provide evidence that our method is effective in mitigating biases based on gender, ethnicity, and age. We also show that an automatic bias evaluation performed by the GPT4o is not significantly statistically distinct from a human evaluation. Our evaluation shows promising results, with reliable levels of agreement between evaluators and more coverage of protected attributes. Our method has the potential to significantly improve the diversity of images it generates by diffusion-based text-to-image generative models.