Netanel Arussy

2papers

2 Papers

AIFeb 20Code
SOMtime the World Ain$'$t Fair: Violating Fairness Using Self-Organizing Maps

Joseph Bingham, Netanel Arussy, Dvir Aran

Unsupervised representations are widely assumed to be neutral with respect to sensitive attributes when those attributes are withheld from training. We show that this assumption is false. Using SOMtime, a topology-preserving representation method based on high-capacity Self-Organizing Maps, we demonstrate that sensitive attributes such as age and income emerge as dominant latent axes in purely unsupervised embeddings, even when explicitly excluded from the input. On two large-scale real-world datasets (the World Values Survey across five countries and the Census-Income dataset), SOMtime recovers monotonic orderings aligned with withheld sensitive attributes, achieving Spearman correlations of up to 0.85, whereas PCA and UMAP typically remain below 0.23 (with a single exception reaching 0.31), and against t-SNE and autoencoders which achieve at most 0.34. Furthermore, unsupervised segmentation of SOMtime embeddings produces demographically skewed clusters, demonstrating downstream fairness risks without any supervised task. These findings establish that \textit{fairness through unawareness} fails at the representation level for ordinal sensitive attributes and that fairness auditing must extend to unsupervised components of machine learning pipelines. We have made the code available at~ https://github.com/JosephBingham/SOMtime

LGFeb 18
Guide-Guard: Off-Target Predicting in CRISPR Applications

Joseph Bingham, Netanel Arussy, Saman Zonouz

With the introduction of cyber-physical genome sequencing and editing technologies, such as CRISPR, researchers can more easily access tools to investigate and create remedies for a variety of topics in genetics and health science (e.g. agriculture and medicine). As the field advances and grows, new concerns present themselves in the ability to predict the off-target behavior. In this work, we explore the underlying biological and chemical model from a data driven perspective. Additionally, we present a machine learning based solution named \textit{Guide-Guard} to predict the behavior of the system given a gRNA in the CRISPR gene-editing process with 84\% accuracy. This solution is able to be trained on multiple different genes at the same time while retaining accuracy.