Ling Lin

Jingrun Chen, Ling Lin, Zhiwen Zhang et al.

Exciton diffusion length plays a vital role in the function of opto-electronic devices. Oftentimes, the domain occupied by an organic semiconductor is subject to surface measurement error. In many experiments, photoluminescence over the domain is measured and used as the observation data to estimate this length parameter in an inverse manner based on the least square method. However, the result is sometimes found to be sensitive to the surface geometry of the domain. In this paper, we employ a random function representation for the uncertain surface of the domain. After non-dimensionalization, the forward model becomes a diffusion-type equation over the domain whose geometric boundary is subject to small random perturbations. We propose an asymptotic-based method as an approximate forward solver whose accuracy is justified both theoretically and numerically. It only requires solving several deterministic problems over a fixed domain. Therefore, for the same accuracy requirements we tested here, the running time of our approach is more than one order of magnitude smaller than that of directly solving the original stochastic boundary-value problem by the stochastic collocation method. In addition, from numerical results, we find that the correlation length of randomness is important to determine whether a 1D reduced model is a good surrogate for the 2D model.

Ling Lin, Yihang Zhou, Zhanqi Hu et al.

Tuberous sclerosis complex (TSC) manifests as a multisystem disorder with significant neurological implications. This study addresses the critical need for robust classification models tailored to TSC in pediatric patients, introducing QResNet,a novel deep learning model seamlessly integrating conventional convolutional neural networks with quantum neural networks. The model incorporates a two-layer quantum layer (QL), comprising ZZFeatureMap and Ansatz layers, strategically designed for processing classical data within a quantum framework. A comprehensive evaluation, demonstrates the superior performance of QResNet in TSC MRI image classification compared to conventional 3D-ResNet models. These compelling findings underscore the potential of quantum computing to revolutionize medical imaging and diagnostics.Remarkably, this method surpasses conventional CNNs in accuracy and Area Under the Curve (AUC) metrics with the current dataset. Future research endeavors may focus on exploring the scalability and practical implementation of quantum algorithms in real-world medical imaging scenarios.

Ling Lin, Yang Bai, Heng Su et al.

Existing Visual-Language Models (VLMs) have achieved significant progress by being trained on massive-scale datasets, typically under the assumption that data are independent and identically distributed (IID). However, in real-world scenarios, it is often impractical to expect that all data processed by an AI system satisfy this assumption. Furthermore, failure to appropriately handle out-of-distribution (OOD) objects may introduce safety risks in real-world applications (e.g., autonomous driving or medical assistance). Unfortunately, current research has not yet provided valid benchmarks that can comprehensively assess the performance of VLMs in response to OOD data. Therefore, we propose OODBench, a predominantly automated method with minimal human verification, for constructing new benchmarks and evaluating the ability of VLMs to process OOD data. OODBench contains 40K instance-level OOD instance-category pairs, and we show that current VLMs still exhibit notable performance degradation on OODBench, even when the underlying image categories are common. In addition, we propose a reliable automated assessment metric that employs a Basic-to-Advanced Progression of prompted questions to assess the impact of OOD data on questions of varying difficulty more fully. Lastly, we summarize substantial findings and insights to facilitate future research in the acquisition and evaluation of OOD data.

Zhiqiang Cai, Ling Lin, Xiang Zhou

We propose a reinforcement learning (RL) approach to compute the expression of quasi-stationary distribution. Based on the fixed-point formulation of quasi-stationary distribution, we minimize the KL-divergence of two Markovian path distributions induced by the candidate distribution and the true target distribution. To solve this challenging minimization problem by gradient descent, we apply the reinforcement learning technique by introducing the reward and value functions. We derive the corresponding policy gradient theorem and design an actor-critic algorithm to learn the optimal solution and the value function. The numerical examples of finite state Markov chain are tested to demonstrate the new method.

Jens B. Stephansen, Alexander N. Olesen, Mads Olsen et al.

Analysis of sleep for the diagnosis of sleep disorders such as Type-1 Narcolepsy (T1N) currently requires visual inspection of polysomnography records by trained scoring technicians. Here, we used neural networks in approximately 3,000 normal and abnormal sleep recordings to automate sleep stage scoring, producing a hypnodensity graph - a probability distribution conveying more information than classical hypnograms. Accuracy of sleep stage scoring was validated in 70 subjects assessed by six scorers. The best model performed better than any individual scorer (87% versus consensus). It also reliably scores sleep down to 5 instead of 30 second scoring epochs. A T1N marker based on unusual sleep-stage overlaps achieved a specificity of 96% and a sensitivity of 91%, validated in independent datasets. Addition of HLA-DQB1*06:02 typing increased specificity to 99%. Our method can reduce time spent in sleep clinics and automates T1N diagnosis. It also opens the possibility of diagnosing T1N using home sleep studies.