Albin Cassirer

Nan Rosemary Ke, Sara-Jane Dunn, Jorg Bornschein et al. · deepmind, mila

Accurately inferring Gene Regulatory Networks (GRNs) is a critical and challenging task in biology. GRNs model the activatory and inhibitory interactions between genes and are inherently causal in nature. To accurately identify GRNs, perturbational data is required. However, most GRN discovery methods only operate on observational data. Recent advances in neural network-based causal discovery methods have significantly improved causal discovery, including handling interventional data, improvements in performance and scalability. However, applying state-of-the-art (SOTA) causal discovery methods in biology poses challenges, such as noisy data and a large number of samples. Thus, adapting the causal discovery methods is necessary to handle these challenges. In this paper, we introduce DiscoGen, a neural network-based GRN discovery method that can denoise gene expression measurements and handle interventional data. We demonstrate that our model outperforms SOTA neural network-based causal discovery methods.

Aidan Clark, Diego de las Casas, Aurelia Guy et al.

The performance of a language model has been shown to be effectively modeled as a power-law in its parameter count. Here we study the scaling behaviors of Routing Networks: architectures that conditionally use only a subset of their parameters while processing an input. For these models, parameter count and computational requirement form two independent axes along which an increase leads to better performance. In this work we derive and justify scaling laws defined on these two variables which generalize those known for standard language models and describe the performance of a wide range of routing architectures trained via three different techniques. Afterwards we provide two applications of these laws: first deriving an Effective Parameter Count along which all models scale at the same rate, and then using the scaling coefficients to give a quantitative comparison of the three routing techniques considered. Our analysis derives from an extensive evaluation of Routing Networks across five orders of magnitude of size, including models with hundreds of experts and hundreds of billions of parameters.

Jack W. Rae, Sebastian Borgeaud, Trevor Cai et al.

Language modelling provides a step towards intelligent communication systems by harnessing large repositories of written human knowledge to better predict and understand the world. In this paper, we present an analysis of Transformer-based language model performance across a wide range of model scales -- from models with tens of millions of parameters up to a 280 billion parameter model called Gopher. These models are evaluated on 152 diverse tasks, achieving state-of-the-art performance across the majority. Gains from scale are largest in areas such as reading comprehension, fact-checking, and the identification of toxic language, but logical and mathematical reasoning see less benefit. We provide a holistic analysis of the training dataset and model's behaviour, covering the intersection of model scale with bias and toxicity. Finally we discuss the application of language models to AI safety and the mitigation of downstream harms.

Sebastian Borgeaud, Arthur Mensch, Jordan Hoffmann et al.

We enhance auto-regressive language models by conditioning on document chunks retrieved from a large corpus, based on local similarity with preceding tokens. With a $2$ trillion token database, our Retrieval-Enhanced Transformer (RETRO) obtains comparable performance to GPT-3 and Jurassic-1 on the Pile, despite using 25$\times$ fewer parameters. After fine-tuning, RETRO performance translates to downstream knowledge-intensive tasks such as question answering. RETRO combines a frozen Bert retriever, a differentiable encoder and a chunked cross-attention mechanism to predict tokens based on an order of magnitude more data than what is typically consumed during training. We typically train RETRO from scratch, yet can also rapidly RETROfit pre-trained transformers with retrieval and still achieve good performance. Our work opens up new avenues for improving language models through explicit memory at unprecedented scale.

Albin Cassirer, Gabriel Barth-Maron, Eugene Brevdo et al.

A central component of training in Reinforcement Learning (RL) is Experience: the data used for training. The mechanisms used to generate and consume this data have an important effect on the performance of RL algorithms. In this paper, we introduce Reverb: an efficient, extensible, and easy to use system designed specifically for experience replay in RL. Reverb is designed to work efficiently in distributed configurations with up to thousands of concurrent clients. The flexible API provides users with the tools to easily and accurately configure the replay buffer. It includes strategies for selecting and removing elements from the buffer, as well as options for controlling the ratio between sampled and inserted elements. This paper presents the core design of Reverb, gives examples of how it can be applied, and provides empirical results of Reverb's performance characteristics.

Pauline Luc, Aidan Clark, Sander Dieleman et al.

Recent breakthroughs in adversarial generative modeling have led to models capable of producing video samples of high quality, even on large and complex datasets of real-world video. In this work, we focus on the task of video prediction, where given a sequence of frames extracted from a video, the goal is to generate a plausible future sequence. We first improve the state of the art by performing a systematic empirical study of discriminator decompositions and proposing an architecture that yields faster convergence and higher performance than previous approaches. We then analyze recurrent units in the generator, and propose a novel recurrent unit which transforms its past hidden state according to predicted motion-like features, and refines it to handle dis-occlusions, scene changes and other complex behavior. We show that this recurrent unit consistently outperforms previous designs. Our final model leads to a leap in the state-of-the-art performance, obtaining a test set Frechet Video Distance of 25.7, down from 69.2, on the large-scale Kinetics-600 dataset.

Ian Osband, John Aslanides, Albin Cassirer

Dealing with uncertainty is essential for efficient reinforcement learning. There is a growing literature on uncertainty estimation for deep learning from fixed datasets, but many of the most popular approaches are poorly-suited to sequential decision problems. Other methods, such as bootstrap sampling, have no mechanism for uncertainty that does not come from the observed data. We highlight why this can be a crucial shortcoming and propose a simple remedy through addition of a randomized untrainable `prior' network to each ensemble member. We prove that this approach is efficient with linear representations, provide simple illustrations of its efficacy with nonlinear representations and show that this approach scales to large-scale problems far better than previous attempts.