Lei Wei

Chenxi Wang, Ruiyang Huang, Jiayan Sun et al.

Latent-based multi-agent systems replace parts of explicit inter-agent communication with hidden representations, offering a new direction for efficient and flexible agent collaboration. However, moving coordination into latent space may also move attacks beyond the reach of visible-text inspection. In this paper, we study whether latent states can carry attack-associated information that remains effective during clean executions. To examine this question, we introduce a latent attack framework that reactivates attack-induced effects through latent interventions without reusing adversarial text. Extensive experiments show that the resulting latent-only attacks can substantially degrade task performance in clean executions, especially when applied to inter-agent KV-cache handoffs rather than local hidden states. Further control analyses indicate that this degradation cannot be reduced to arbitrary perturbations or invalid generation. Overall, our findings suggest that latent-based collaboration does not remove attack risk. It shifts part of the risk into less observable execution states, calling for safeguards beyond visible-text inspection.

Lanbo Lin, Jiayao Liu, Tianyuan Yang et al.

Evaluating agentic AI on open-ended professional tasks faces a fundamental dilemma between rigor and flexibility. Static rubrics provide rigorous, reproducible assessment but fail to accommodate diverse valid response strategies, while LLM-as-a-judge approaches adapt to individual responses yet suffer from instability and bias. Human experts address this dilemma by combining domain-grounded principles with dynamic, claim-level assessment. Inspired by this process, we propose JADE, a two-layer evaluation framework. Layer 1 encodes expert knowledge as a predefined set of evaluation skills, providing stable evaluation criteria. Layer 2 performs report-specific, claim-level evaluation to flexibly assess diverse reasoning strategies, with evidence-dependency gating to invalidate conclusions built on refuted claims. Experiments on BizBench show that JADE improves evaluation stability and reveals critical agent failure modes missed by holistic LLM-based evaluators. We further demonstrate strong alignment with expert-authored rubrics and effective transfer to a medical-domain benchmark, validating JADE across professional domains. Our code is publicly available at https://github.com/smiling-world/JADE.

Stephanie Ng, CP Lim, SueJen Looi et al.

Hazard, as an abstract concept, is typically defined through cognitive-level logical reasoning rather than concrete examples. In contrast, existing hazard detection systems rely on predefined hazard categories and require intensive collection of labelled examples within detection or classification architectures. This approach faces three fundamental challenges when addressing abstract safety concepts: (1) noisy and sparse training data, (2) dynamically evolving definitions that change across contexts and time, and (3) limited generalisation to unseen or novel scenarios. To address these limitations, we present the CompliVision dataset, the first general-purpose hazard dataset designed for rule-based compliance assessment, along with a baseline framework for hazard evaluation. Our key innovation is decoupling the hazard concept from image-based examples by expressing safety requirements through language-based rules. We ground our approach in authoritative domain regulations and ISO standards to define diverse hazard concepts across multiple domains. The CompliVision dataset comprises 3,006 images spanning traffic, construction, and warehouse environments, with each image annotated for compliance against specific safety rules, accompanied by natural language explanations highlighting the supporting visual evidence. To achieve robust generalisation, we develop an active learning framework to more effectively guide and refine vision-language models in assessing hazard compliance. While state-of-the-art VLMs demonstrate strong capabilities, they struggle with the fine-grained, context-dependent interpretation required for accurate safety assessment. We proposed a general hazard detection framework to address this limitation which combines LLaVA-based visual reasoning with with human-in-the-loop feedback.

Dasith de Silva Edirimuni, Xuequan Lu, Gang Li et al.

Point cloud filtering is a fundamental 3D vision task, which aims to remove noise while recovering the underlying clean surfaces. State-of-the-art methods remove noise by moving noisy points along stochastic trajectories to the clean surfaces. These methods often require regularization within the training objective and/or during post-processing, to ensure fidelity. In this paper, we introduce StraightPCF, a new deep learning based method for point cloud filtering. It works by moving noisy points along straight paths, thus reducing discretization errors while ensuring faster convergence to the clean surfaces. We model noisy patches as intermediate states between high noise patch variants and their clean counterparts, and design the VelocityModule to infer a constant flow velocity from the former to the latter. This constant flow leads to straight filtering trajectories. In addition, we introduce a DistanceModule that scales the straight trajectory using an estimated distance scalar to attain convergence near the clean surface. Our network is lightweight and only has $\sim530K$ parameters, being 17% of IterativePFN (a most recent point cloud filtering network). Extensive experiments on both synthetic and real-world data show our method achieves state-of-the-art results. Our method also demonstrates nice distributions of filtered points without the need for regularization. The implementation code can be found at: https://github.com/ddsediri/StraightPCF.

Lei Wei, Jinpeng Ou, Xiao Peng et al.

Large language models (LLMs) have demonstrated remarkable capabilities in function calling for autonomous agents, yet current mechanisms lack explicit reasoning transparency during parameter generation, particularly for complex functions with interdependent parameters. While existing approaches like chain-of-thought prompting operate at the agent level, they fail to provide fine-grained reasoning guidance for individual function parameters. To address these limitations, we propose Think-Augmented Function Calling (TAFC), a novel framework that enhances function calling accuracy through explicit reasoning at both function and parameter levels. Our method introduces a universal "think" parameter augmentation that enables models to articulate their decision-making process, with dynamic optimization for parameter descriptions to improve reasoning quality. For complex parameters, TAFC automatically triggers granular reasoning based on complexity scoring, ensuring appropriate justification for critical decisions. Additionally, we propose reasoning-guided optimization to align generated reasoning with human expectations. TAFC requires no architectural modifications to existing LLMs while maintaining full API compatibility. Evaluation on ToolBench across proprietary and open-source models demonstrates significant improvements in parameter generation accuracy and reasoning coherence for multi-parameter functions, while providing enhanced interpretability for debugging AI agent behaviors.

Yuezhe Zhang, Luqian Bai, Mengting Yu et al.

Data acquisition through mobile phones remains a challenge for 3D Gaussian Splatting (3DGS). In this work we target the object-centered scenario and enable reliable mobile acquisition by providing on-device capture guidance and recording onboard sensor signals for offline reconstruction. After the calibration step, the device orientations are aligned to a baseline frame to obtain relative poses, and the optical axis of the camera is mapped to an object-centered spherical grid for uniform viewpoint indexing. To curb polar sampling bias, we compute area-weighted spherical coverage in real-time and guide the user's motion accordingly. We compare the proposed method with RealityScan and the free-capture strategy. Our method achieves superior reconstruction quality using fewer input images compared to free capture and RealityScan. Further analysis shows that the proposed method is able to obtain more comprehensive and uniform viewpoint coverage during object-centered acquisition.

Erpai Luo, Jinmeng Jia, Yifan Xiong et al.

The rise of large language models and multi-agent systems has sparked growing interest in AI scientists capable of autonomous biological research. However, existing benchmarks either focus on reasoning without data or on data analysis with predefined statistical answers, lacking realistic, data-driven evaluation settings. Here, we introduce the Biological AI Scientist Benchmark (BaisBench), a benchmark designed to assess AI scientists' ability to generate biological discoveries through data analysis and reasoning with external knowledge. BaisBench comprises two tasks: cell type annotation on 31 expert-labeled single-cell datasets, and scientific discovery through answering 198 multiple-choice questions derived from the biological insights of 41 recent single-cell studies. Systematic experiments on state-of-the-art AI scientists and LLM agents showed that while promising, current models still substantially underperform human experts on both tasks. We hope BaisBench will fill this gap and serve as a foundation for advancing and evaluating AI models for scientific discovery. The benchmark can be found at: https://github.com/EperLuo/BaisBench.

Tianhong Zhou, Yin Xu, Yingtao Zhu et al.

Vision-language models (VLMs) exhibit strong zero-shot generalization on natural images and show early promise in interpretable medical image analysis. However, existing benchmarks do not systematically evaluate whether these models truly reason like human clinicians or merely imitate superficial patterns. To address this gap, we propose DrVD-Bench, the first multimodal benchmark for clinical visual reasoning. DrVD-Bench consists of three modules: Visual Evidence Comprehension, Reasoning Trajectory Assessment, and Report Generation Evaluation, comprising a total of 7,789 image-question pairs. Our benchmark covers 20 task types, 17 diagnostic categories, and five imaging modalities-CT, MRI, ultrasound, radiography, and pathology. DrVD-Bench is explicitly structured to reflect the clinical reasoning workflow from modality recognition to lesion identification and diagnosis. We benchmark 19 VLMs, including general-purpose and medical-specific, open-source and proprietary models, and observe that performance drops sharply as reasoning complexity increases. While some models begin to exhibit traces of human-like reasoning, they often still rely on shortcut correlations rather than grounded visual understanding. DrVD-Bench offers a rigorous and structured evaluation framework to guide the development of clinically trustworthy VLMs.

Zheyang Huang, Jagannath Aryal, Saeid Nahavandi et al.

Cross-view geo-localization determines the location of a query image, captured by a drone or ground-based camera, by matching it to a geo-referenced satellite image. While traditional approaches focus on image-level localization, many applications, such as search-and-rescue, infrastructure inspection, and precision delivery, demand object-level accuracy. This enables users to prompt a specific object with a single click on a drone image to retrieve precise geo-tagged information of the object. However, variations in viewpoints, timing, and imaging conditions pose significant challenges, especially when identifying visually similar objects in extensive satellite imagery. To address these challenges, we propose an Object-level Cross-view Geo-localization Network (OCGNet). It integrates user-specified click locations using Gaussian Kernel Transfer (GKT) to preserve location information throughout the network. This cue is dually embedded into the feature encoder and feature matching blocks, ensuring robust object-specific localization. Additionally, OCGNet incorporates a Location Enhancement (LE) module and a Multi-Head Cross Attention (MHCA) module to adaptively emphasize object-specific features or expand focus to relevant contextual regions when necessary. OCGNet achieves state-of-the-art performance on a public dataset, CVOGL. It also demonstrates few-shot learning capabilities, effectively generalizing from limited examples, making it suitable for diverse applications (https://github.com/ZheyangH/OCGNet).

Erpai Luo, Minsheng Hao, Lei Wei et al.

Single-cell RNA sequencing (scRNA-seq) data are important for studying the laws of life at single-cell level. However, it is still challenging to obtain enough high-quality scRNA-seq data. To mitigate the limited availability of data, generative models have been proposed to computationally generate synthetic scRNA-seq data. Nevertheless, the data generated with current models are not very realistic yet, especially when we need to generate data with controlled conditions. In the meantime, the Diffusion models have shown their power in generating data at high fidelity, providing a new opportunity for scRNA-seq generation. In this study, we developed scDiffusion, a generative model combining diffusion model and foundation model to generate high-quality scRNA-seq data with controlled conditions. We designed multiple classifiers to guide the diffusion process simultaneously, enabling scDiffusion to generate data under multiple condition combinations. We also proposed a new control strategy called Gradient Interpolation. This strategy allows the model to generate continuous trajectories of cell development from a given cell state. Experiments showed that scDiffusion can generate single-cell gene expression data closely resembling real scRNA-seq data. Also, scDiffusion can conditionally produce data on specific cell types including rare cell types. Furthermore, we could use the multiple-condition generation of scDiffusion to generate cell type that was out of the training data. Leveraging the Gradient Interpolation strategy, we generated a continuous developmental trajectory of mouse embryonic cells. These experiments demonstrate that scDiffusion is a powerful tool for augmenting the real scRNA-seq data and can provide insights into cell fate research.

Lei Wei, Xu Dong, Xiao Peng et al.

Large language models deployed as autonomous agents face critical memory limitations, lacking selective forgetting mechanisms that lead to either catastrophic forgetting at context boundaries or information overload within them. While human memory naturally balances retention and forgetting through adaptive decay processes, current AI systems employ binary retention strategies that preserve everything or lose it entirely. We propose FadeMem, a biologically-inspired agent memory architecture that incorporates active forgetting mechanisms mirroring human cognitive efficiency. FadeMem implements differential decay rates across a dual-layer memory hierarchy, where retention is governed by adaptive exponential decay functions modulated by semantic relevance, access frequency, and temporal patterns. Through LLM-guided conflict resolution and intelligent memory fusion, our system consolidates related information while allowing irrelevant details to fade. Experiments on Multi-Session Chat, LoCoMo, and LTI-Bench demonstrate superior multi-hop reasoning and retrieval with 45\% storage reduction, validating the effectiveness of biologically-inspired forgetting in agent memory systems.

Yao Cheng, Zhe Han, Fengyang Jiang et al.

This paper addresses the high demand in advanced intelligent robot navigation for a more holistic understanding of spatial environments, by introducing a novel system that harnesses the capabilities of Large Language Models (LLMs) to construct hierarchical 3D Scene Graphs (3DSGs) for indoor scenarios. The proposed framework constructs 3DSGs consisting of a fundamental layer with rich metric-semantic information, an object layer featuring precise point-cloud representation of object nodes as well as visual descriptors, and higher layers of room, floor, and building nodes. Thanks to the innovative application of LLMs, not only object nodes but also nodes of higher layers, e.g., room nodes, are annotated in an intelligent and accurate manner. A polling mechanism for room classification using LLMs is proposed to enhance the accuracy and reliability of the room node annotation. Thorough numerical experiments demonstrate the system's ability to integrate semantic descriptions with geometric data, creating an accurate and comprehensive representation of the environment instrumental for context-aware navigation and task planning.

Yuting Zhang, Tiantian Geng, Luoying Hao et al.

Contemporary cardiovascular management involves complex consideration and integration of multimodal cardiac datasets, where each modality provides distinct but complementary physiological characteristics. While the effective integration of multiple modalities could yield a holistic clinical profile that accurately models the true clinical situation with respect to data modalities and their relatives weightings, current methodologies remain limited by: 1) the scarcity of patient- and time-aligned multimodal data; 2) reliance on isolated single-modality or rigid multimodal input combinations; 3) alignment strategies that prioritize cross-modal similarity over complementarity; and 4) a narrow single-task focus. In response to these limitations, a comprehensive multimodal dataset was curated for immediate application, integrating laboratory test results, electrocardiograms, and echocardiograms with clinical outcomes. Subsequently, a unified framework, Textual Guidance Multimodal fusion for Multiple cardiac tasks (TGMM), was proposed. TGMM incorporated three key components: 1) a MedFlexFusion module designed to capture the unique and complementary characteristics of medical modalities and dynamically integrate data from diverse cardiac sources and their combinations; 2) a textual guidance module to derive task-relevant representations tailored to diverse clinical objectives, including heart disease diagnosis, risk stratification and information retrieval; and 3) a response module to produce final decisions for all these tasks. Furthermore, this study systematically explored key features across multiple modalities and elucidated their synergistic contributions in clinical decision-making. Extensive experiments showed that TGMM outperformed state-of-the-art methods across multiple clinical tasks, with additional validation confirming its robustness on another public dataset.

Dasith de Silva Edirimuni, Xuequan Lu, Ajmal Saeed Mian et al.

Point cloud capture processes are error-prone and introduce noisy artifacts that necessitate filtering/denoising. Recent filtering methods often suffer from point clustering or noise retaining issues. In this paper, we propose Hybrid Point Cloud Filtering ($\textbf{HybridPF}$) that considers both short-range and long-range filtering trajectories when removing noise. It is well established that short range scores, given by $\nabla_{x}\log p(x_t)$, may provide the necessary displacements to move noisy points to the underlying clean surface. By contrast, long range velocity flows approximate constant displacements directed from a high noise variant patch $x_0$ towards the corresponding clean surface $x_1$. Here, noisy patches $x_t$ are viewed as intermediate states between the high noise variant and the clean patches. Our intuition is that long range information from velocity flow models can guide the short range scores to align more closely with the clean points. In turn, score models generally provide a quicker convergence to the clean surface. Specifically, we devise two parallel modules, the ShortModule and LongModule, each consisting of an Encoder-Decoder pair to respectively account for short-range scores and long-range flows. We find that short-range scores, guided by long-range features, yield filtered point clouds with good point distributions and convergence near the clean surface. We design a joint loss function to simultaneously train the ShortModule and LongModule, in an end-to-end manner. Finally, we identify a key weakness in current displacement based methods, limitations on the decoder architecture, and propose a dynamic graph convolutional decoder to improve the inference process. Comprehensive experiments demonstrate that our HybridPF achieves state-of-the-art results while enabling faster inference speed.

Mo Chen, Minsheng Hao, Xinquan Liu et al.

Cells in multicellular organisms coordinate to form functional and structural niches. With spatial transcriptomics enabling gene expression profiling in spatial contexts, it has been revealed that spatial niches serve as cohesive and recurrent units in physiological and pathological processes. These observations suggest universal tissue organization principles encoded by conserved niche patterns, and call for a query-based niche analytical paradigm beyond current computational tools. In this work, we defined the Niche Query Task, which is to identify similar niches across ST samples given a niche of interest (NOI). We further developed QueST, a specialized method for solving this task. QueST models each niche as a subgraph, uses contrastive learning to learn discriminative niche embeddings, and incorporates adversarial training to mitigate batch effects. In simulations and benchmark datasets, QueST outperformed existing methods repurposed for niche querying, accurately capturing niche structures in heterogeneous environments and demonstrating strong generalizability across diverse sequencing platforms. Applied to tertiary lymphoid structures in renal and lung cancers, QueST revealed functionally distinct niches associated with patient prognosis and uncovered conserved and divergent spatial architectures across cancer types. These results demonstrate that QueST enables systematic, quantitative profiling of spatial niches across samples, providing a powerful tool to dissect spatial tissue architecture in health and disease.

Dandan Zhang, Yu Zheng, Qiang Li et al.

To accurately pour drinks into various containers is an essential skill for service robots. However, drink pouring is a dynamic process and difficult to model. Traditional deep imitation learning techniques for implementing autonomous robotic pouring have an inherent black-box effect and require a large amount of demonstration data for model training. To address these issues, an Explainable Hierarchical Imitation Learning (EHIL) method is proposed in this paper such that a robot can learn high-level general knowledge and execute low-level actions across multiple drink pouring scenarios. Moreover, with EHIL, a logical graph can be constructed for task execution, through which the decision-making process for action generation can be made explainable to users and the causes of failure can be traced out. Based on the logical graph, the framework is manipulable to achieve different targets while the adaptability to unseen scenarios can be achieved in an explainable manner. A series of experiments have been conducted to verify the effectiveness of the proposed method. Results indicate that EHIL outperforms the traditional behavior cloning method in terms of success rate, adaptability, manipulability and explainability.

Junjie Wang, Bihuan Chen, Lei Wei et al.

In recent years, coverage-based greybox fuzzing has proven itself to be one of the most effective techniques for finding security bugs in practice. Particularly, American Fuzzy Lop (AFL for short) is deemed to be a great success in fuzzing relatively simple test inputs. Unfortunately, when it meets structured test inputs such as XML and JavaScript, those grammar-blind trimming and mutation strategies in AFL hinder the effectiveness and efficiency. To this end, we propose a grammar-aware coverage-based greybox fuzzing approach to fuzz programs that process structured inputs. Given the grammar (which is often publicly available) of test inputs, we introduce a grammar-aware trimming strategy to trim test inputs at the tree level using the abstract syntax trees (ASTs) of parsed test inputs. Further, we introduce two grammar-aware mutation strategies (i.e., enhanced dictionary-based mutation and tree-based mutation). Specifically, tree-based mutation works via replacing subtrees using the ASTs of parsed test inputs. Equipped with grammar-awareness, our approach can carry the fuzzing exploration into width and depth. We implemented our approach as an extension to AFL, named Superion; and evaluated the effectiveness of Superion on real-life large-scale programs (a XML engine libplist and three JavaScript engines WebKit, Jerryscript and ChakraCore). Our results have demonstrated that Superion can improve the code coverage (i.e., 16.7% and 8.8% in line and function coverage) and bug-finding capability (i.e., 31 new bugs, among which we discovered 21 new vulnerabilities with 16 CVEs assigned and 3.2K USD bug bounty rewards received) over AFL and jsfunfuzz. We also demonstrated the effectiveness of our grammar-aware trimming and mutation.