Maoquan Zhang

Lin Song, Wenbo Li, Guoqing Ma et al.

We present JoyAI-Image, a unified multimodal foundation model for visual understanding, text-to-image generation, and instruction-guided image editing. JoyAI-Image couples a spatially enhanced Multimodal Large Language Model (MLLM) with a Multimodal Diffusion Transformer (MMDiT), allowing perception and generation to interact through a shared multimodal interface. Around this architecture, we build a scalable training recipe that combines unified instruction tuning, long-text rendering supervision, spatially grounded data, and both general and spatial editing signals. This design gives the model broad multimodal capability while strengthening geometry-aware reasoning and controllable visual synthesis. Experiments across understanding, generation, long-text rendering, and editing benchmarks show that JoyAI-Image achieves state-of-the-art or highly competitive performance. More importantly, the bidirectional loop between enhanced understanding, controllable spatial editing, and novel-view-assisted reasoning enables the model to move beyond general visual competence toward stronger spatial intelligence. These results suggest a promising path for unified visual models in downstream applications such as vision-language-action systems and world models.

Maoquan Zhang, Bisser Raytchev, Xiujuan Sun

Medical image segmentation requires not only accuracy but also robustness under challenging imaging conditions. In this study, we show that a carefully configured DeepLabv3 model can achieve high performance in segmenting induced pluripotent stem (iPS) cell colonies, and, under our experimental conditions, outperforms large-scale foundation models such as SAM2 and its medical variant MedSAM2 without structural modifications. These results suggest that, for specialized tasks characterized by subtle, low-contrast boundaries, increased model complexity does not necessarily translate to better performance. Our work revisits the assumption that ever-larger and more generalized architectures are always preferable, and provides evidence that appropriately adapted, simpler models may offer strong accuracy and practical reliability in domain-specific biomedical applications. We also offer an open-source implementation that includes strategies for small datasets and domain-specific encoding, with the aim of supporting further advances in semantic segmentation for regenerative medicine and related fields.

Maoquan Zhang, Bisser Raytchev, Xiujuan Sun

LEARN is a layout-aware diffusion framework designed to generate pedagogically aligned illustrations for STEM education. It leverages a curated BookCover dataset that provides narrative layouts and structured visual cues, enabling the model to depict abstract and sequential scientific concepts with strong semantic alignment. Through layout-conditioned generation, contrastive visual-semantic training, and prompt modulation, LEARN produces coherent visual sequences that support mid-to-high-level reasoning in line with Bloom's taxonomy while reducing extraneous cognitive load as emphasized by Cognitive Load Theory. By fostering spatially organized and story-driven narratives, the framework counters fragmented attention often induced by short-form media and promotes sustained conceptual focus. Beyond static diagrams, LEARN demonstrates potential for integration with multimodal systems and curriculum-linked knowledge graphs to create adaptive, exploratory educational content. As the first generative approach to unify layout-based storytelling, semantic structure learning, and cognitive scaffolding, LEARN represents a novel direction for generative AI in education. The code and dataset will be released to facilitate future research and practical deployment.