Devansh Arora

Aditya Hemant Shahane, Anuj Kumar Sirohi, Devansh Arora et al.

Bridging molecular structures and natural language is essential for controllable design. Autoregressive models struggle with long-range dependencies, while standard diffusion processes apply uniform corruption across positions, which can distort structurally informative tokens. We present BiMol-Diff, a unified diffusion framework for the paired tasks of text-conditioned molecule generation and molecule captioning. Our key component is a token-aware noise schedule that assigns position-dependent corruption based on token recovery difficulty, preserving harder-to-recover substructures during the forward process. On ChEBI-20 and M3-20M, BiMol-Diff improves molecule reconstruction with a 15.4% relative gain in Exact Match and achieves strong captioning results, attaining best BLEU and BERTScore among compared baselines. These results indicate token-aware noising improves fidelity in molecular structure-language modelling.

Devansh Arora, Nitin Kumar, Sukrit Gupta

Image segmentation is an important and widely performed task in computer vision. Accomplishing effective image segmentation in diverse settings often requires custom model architectures and loss functions. A set of models that specialize in segmenting thin tubular structures are topology preservation-based loss functions. These models often utilize a pixel skeletonization process claimed to generate more precise segmentation masks of thin tubes and better capture the structures that other models often miss. One such model, Skeleton Recall Loss (SRL) proposed by Kirchhoff et al.~\cite {kirchhoff2024srl}, was stated to produce state-of-the-art results on benchmark tubular datasets. In this work, we performed a theoretical analysis of the gradients for the SRL loss. Upon comparing the performance of the proposed method on some of the tubular datasets (used in the original work, along with some additional datasets), we found that the performance of SRL-based segmentation models did not exceed traditional baseline models. By providing both a theoretical explanation and empirical evidence, this work critically evaluates the limitations of topology-based loss functions, offering valuable insights for researchers aiming to develop more effective segmentation models for complex tubular structures.