Xi Wu

Jing Hu, Ziwei Luo, Chengming Feng et al.

Most existing Image-to-Image Translation (I2IT) methods generate images in a single run of a deep learning (DL) model. However, designing such a single-step model is always challenging, requiring a huge number of parameters and easily falling into bad global minimums and overfitting. In this work, we reformulate I2IT as a step-wise decision-making problem via deep reinforcement learning (DRL) and propose a novel framework that performs RL-based I2IT (RL-I2IT). The key feature in the RL-I2IT framework is to decompose a monolithic learning process into small steps with a lightweight model to progressively transform a source image successively to a target image. Considering that it is challenging to handle high dimensional continuous state and action spaces in the conventional RL framework, we introduce meta policy with a new concept Plan to the standard Actor-Critic model, which is of a lower dimension than the original image and can facilitate the actor to generate a tractable high dimensional action. In the RL-I2IT framework, we also employ a task-specific auxiliary learning strategy to stabilize the training process and improve the performance of the corresponding task. Experiments on several I2IT tasks demonstrate the effectiveness and robustness of the proposed method when facing high-dimensional continuous action space problems. Our implementation of the RL-I2IT framework is available at https://github.com/Algolzw/SPAC-Deformable-Registration.

Tingyu Zhao, Bo Peng, Yuan Sun et al.

Recently, advancements in deep learning-based superpixel segmentation methods have brought about improvements in both the efficiency and the performance of segmentation. However, a significant challenge remains in generating superpixels that strictly adhere to object boundaries while conveying rich visual significance, especially when cross-surface color correlations may interfere with objects. Drawing inspiration from neural structure and visual mechanisms, we propose a biological network architecture comprising an Enhanced Screening Module (ESM) and a novel Boundary-Aware Label (BAL) for superpixel segmentation. The ESM enhances semantic information by simulating the interactive projection mechanisms of the visual cortex. Additionally, the BAL emulates the spatial frequency characteristics of visual cortical cells to facilitate the generation of superpixels with strong boundary adherence. We demonstrate the effectiveness of our approach through evaluations on both the BSDS500 dataset and the NYUv2 dataset.

Chengming Feng, Jing Hu, Xin Wang et al.

Controlling the degree of stylization in the Neural Style Transfer (NST) is a little tricky since it usually needs hand-engineering on hyper-parameters. In this paper, we propose the first deep Reinforcement Learning (RL) based architecture that splits one-step style transfer into a step-wise process for the NST task. Our RL-based method tends to preserve more details and structures of the content image in early steps, and synthesize more style patterns in later steps. It is a user-easily-controlled style-transfer method. Additionally, as our RL-based model performs the stylization progressively, it is lightweight and has lower computational complexity than existing one-step Deep Learning (DL) based models. Experimental results demonstrate the effectiveness and robustness of our method.

Lu Wen, Wenxia Yin, Zhenghao Feng et al.

Radiation therapy is the mainstay treatment for cervical cancer, and its ultimate goal is to ensure the planning target volume (PTV) reaches the prescribed dose while reducing dose deposition of organs-at-risk (OARs) as much as possible. To achieve these clinical requirements, the medical physicist needs to manually tweak the radiotherapy plan repeatedly in a trial-anderror manner until finding the optimal one in the clinic. However, such trial-and-error processes are quite time-consuming, and the quality of plans highly depends on the experience of the medical physicist. In this paper, we propose an end-to-end Attentionbased Residual Adversarial Network with deep supervision, namely ARANet, to automatically predict the 3D dose distribution of cervical cancer. Specifically, given the computer tomography (CT) images and their corresponding segmentation masks of PTV and OARs, ARANet employs a prediction network to generate the dose maps. We also utilize a multi-scale residual attention module and deep supervision mechanism to enforce the prediction network to extract more valuable dose features while suppressing irrelevant information. Our proposed method is validated on an in-house dataset including 54 cervical cancer patients, and experimental results have demonstrated its obvious superiority compared to other state-of-the-art methods.

Hang Yang, Hao Chen, Hui Guo et al.

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face significant challenges in medical question answering, particularly in understanding domain-specific terminologies and performing complex reasoning. These limitations undermine their effectiveness in critical medical applications. To address these issues, we propose a novel approach incorporating similar case generation within a multi-agent medical question-answering (MedQA) system. Specifically, we leverage the Llama3.1:70B model, a state-of-the-art LLM, in a multi-agent architecture to enhance performance on the MedQA dataset using zero-shot learning. Our method capitalizes on the model's inherent medical knowledge and reasoning capabilities, eliminating the need for additional training data. Experimental results show substantial performance gains over existing benchmark models, with improvements of 7% in both accuracy and F1-score across various medical QA tasks. Furthermore, we examine the model's interpretability and reliability in addressing complex medical queries. This research not only offers a robust solution for medical question answering but also establishes a foundation for broader applications of LLMs in the medical domain.

Chengxu Wu, Qinrui Fan, Shu Hu et al.

An important development direction in the Single-Image Super-Resolution (SISR) algorithms is to improve the efficiency of the algorithms. Recently, efficient Super-Resolution (SR) research focuses on reducing model complexity and improving efficiency through improved deep small kernel convolution, leading to a small receptive field. The large receptive field obtained by large kernel convolution can significantly improve image quality, but the computational cost is too high. To improve the reconstruction details of efficient super-resolution reconstruction, we propose a Symmetric Visual Attention Network (SVAN) by applying large receptive fields. The SVAN decomposes a large kernel convolution into three different combinations of convolution operations and combines them with an attention mechanism to form a Symmetric Large Kernel Attention Block (SLKAB), which forms a symmetric attention block with a bottleneck structure by the size of the receptive field in the convolution combination to extract depth features effectively as the basic component of the SVAN. Our network gets a large receptive field while minimizing the number of parameters and improving the perceptual ability of the model. The experimental results show that the proposed SVAN can obtain high-quality super-resolution reconstruction results using only about 30% of the parameters of existing SOTA methods.

Zhang Qixiang, Yang Yuxiang, Zu Chen et al.

Semi-supervised learning (SSL) is a popular solution to alleviate the high annotation cost in medical image classification. As a main branch of SSL, consistency regularization engages in imposing consensus between the predictions of a single sample from different views, termed as Absolute Location consistency (AL-c). However, only AL-c may be insufficient. Just like when diagnosing a case in practice, besides the case itself, the doctor usually refers to certain related trustworthy cases to make more reliable decisions.Therefore, we argue that solely relying on AL-c may ignore the relative differences across samples, which we interpret as relative locations, and only exploit limited information from one perspective. To address this issue, we propose a Sample Consistency Mean Teacher (SCMT) which not only incorporates AL c but also additionally enforces consistency between the samples' relative similarities to its related samples, called Relative Location consistency (RL c). AL c and RL c conduct consistency regularization from two different perspectives, jointly extracting more diverse semantic information for classification. On the other hand, due to the highly similar structures in medical images, the sample distribution could be overly dense in feature space, making their relative locations susceptible to noise. To tackle this problem, we further develop a Sample Scatter Mean Teacher (SSMT) by utilizing contrastive learning to sparsify the sample distribution and obtain robust and effective relative locations. Extensive experiments on different datasets demonstrate the superiority of our method.

Quanyu Liao, Xin Wang, Bin Kong et al.

Deep neural networks have been demonstrated to be vulnerable to adversarial attacks: subtle perturbation can completely change prediction result. The vulnerability has led to a surge of research in this direction, including adversarial attacks on object detection networks. However, previous studies are dedicated to attacking anchor-based object detectors. In this paper, we present the first adversarial attack on anchor-free object detectors. It conducts category-wise, instead of previously instance-wise, attacks on object detectors, and leverages high-level semantic information to efficiently generate transferable adversarial examples, which can also be transferred to attack other object detectors, even anchor-based detectors such as Faster R-CNN. Experimental results on two benchmark datasets demonstrate that our proposed method achieves state-of-the-art performance and transferability.

Quanyu Liao, Yuezun Li, Xin Wang et al.

Fooling people with highly realistic fake images generated with Deepfake or GANs brings a great social disturbance to our society. Many methods have been proposed to detect fake images, but they are vulnerable to adversarial perturbations -- intentionally designed noises that can lead to the wrong prediction. Existing methods of attacking fake image detectors usually generate adversarial perturbations to perturb almost the entire image. This is redundant and increases the perceptibility of perturbations. In this paper, we propose a novel method to disrupt the fake image detection by determining key pixels to a fake image detector and attacking only the key pixels, which results in the $L_0$ and the $L_2$ norms of adversarial perturbations much less than those of existing works. Experiments on two public datasets with three fake image detectors indicate that our proposed method achieves state-of-the-art performance in both white-box and black-box attacks.

Quanyu Liao, Xin Wang, Bin Kong et al.

The deep neural network is vulnerable to adversarial examples. Adding imperceptible adversarial perturbations to images is enough to make them fail. Most existing research focuses on attacking image classifiers or anchor-based object detectors, but they generate globally perturbation on the whole image, which is unnecessary. In our work, we leverage higher-level semantic information to generate high aggressive local perturbations for anchor-free object detectors. As a result, it is less computationally intensive and achieves a higher black-box attack as well as transferring attack performance. The adversarial examples generated by our method are not only capable of attacking anchor-free object detectors, but also able to be transferred to attack anchor-based object detector.

Shanhui Sun, Jing Hu, Mingqing Yao et al.

The crucial components of a conventional image registration method are the choice of the right feature representations and similarity measures. These two components, although elaborately designed, are somewhat handcrafted using human knowledge. To this end, these two components are tackled in an end-to-end manner via reinforcement learning in this work. Specifically, an artificial agent, which is composed of a combined policy and value network, is trained to adjust the moving image toward the right direction. We train this network using an asynchronous reinforcement learning algorithm, where a customized reward function is also leveraged to encourage robust image registration. This trained network is further incorporated with a lookahead inference to improve the registration capability. The advantage of this algorithm is fully demonstrated by our superior performance on clinical MR and CT image pairs to other state-of-the-art medical image registration methods.