Melika Qahqaie

Farid Tasharofi, Fuxin Fan, Melika Qahqaie et al.

Metal artifacts, caused by high-density metallic implants in computed tomography (CT) imaging, severely degrade image quality, complicating diagnosis and treatment planning. While existing deep learning algorithms have achieved notable success in Metal Artifact Reduction (MAR), they often struggle to suppress artifacts while preserving structural details. To address this challenge, we propose FIND-Net (Fourier-Integrated Network with Dictionary Kernels), a novel MAR framework that integrates frequency and spatial domain processing to achieve superior artifact suppression and structural preservation. FIND-Net incorporates Fast Fourier Convolution (FFC) layers and trainable Gaussian filtering, treating MAR as a hybrid task operating in both spatial and frequency domains. This approach enhances global contextual understanding and frequency selectivity, effectively reducing artifacts while maintaining anatomical structures. Experiments on synthetic datasets show that FIND-Net achieves statistically significant improvements over state-of-the-art MAR methods, with a 3.07% MAE reduction, 0.18% SSIM increase, and 0.90% PSNR improvement, confirming robustness across varying artifact complexities. Furthermore, evaluations on real-world clinical CT scans confirm FIND-Net's ability to minimize modifications to clean anatomical regions while effectively suppressing metal-induced distortions. These findings highlight FIND-Net's potential for advancing MAR performance, offering superior structural preservation and improved clinical applicability. Code is available at https://github.com/Farid-Tasharofi/FIND-Net

Mohammad Robaitul Islam Bhuiyan, Sheethal Bhat, Melika Qahqaie et al.

Precise localization and delineation of brain tumors using Magnetic Resonance Imaging (MRI) are essential for planning therapy and guiding surgical decisions. However, most existing approaches rely on task-specific supervised models and are constrained by the limited availability of annotated data. To address this, we propose LoGSAM, a parameter-efficient, detection-driven framework that transforms radiologist dictation into text prompts for foundation-model-based localization and segmentation. Radiologist speech is first transcribed and translated using a pretrained Whisper ASR model, followed by negation-aware clinical NLP to extract tumor-specific textual prompts. These prompts guide text-conditioned tumor localization via a LoRA-adapted vision-language detection model, Grounding DINO (GDINO). The LoRA adaptation updates using 5% of the model parameters, thereby enabling computationally efficient domain adaptation while preserving pretrained cross-modal knowledge. The predicted bounding boxes are used as prompts for MedSAM to generate pixel-level tumor masks without any additional fine-tuning. Conditioning the frozen MedSAM on LoGSAM-derived priors yields a state-of-the-art dice score of 80.32% on BRISC 2025. In addition, we evaluate the full pipeline using German dictations from a board-certified radiologist on 12 unseen MRI scans, achieving 91.7% case-level accuracy. These results highlight the feasibility of constructing a modular, speech-to-segmentation pipeline by intelligently leveraging pretrained foundation models with minimal parameter updates.

Melika Qahqaie, Dominik Neumann, Tobias Heimann et al.

Evaluating lesion evolution in longitudinal CT scans of can cer patients is essential for assessing treatment response, yet establishing reliable lesion correspondence across time remains challenging. Standard bipartite matchers, which rely on geometric proximity, struggle when lesions appear, disappear, merge, or split. We propose a registration-aware matcher based on unbalanced optimal transport (UOT) that accommodates unequal lesion mass and adapts priors to patient-level tumor-load changes. Our transport cost blends (i) size-normalized geometry, (ii) local registration trust from the deformation-field Jacobian, and (iii) optional patch-level appearance consistency. The resulting transport plan is sparsified by relative pruning, yielding one-to-one matches as well as new, disappearing, merging, and splitting lesions without retraining or heuristic rules. On longitudinal CT data, our approach achieves consistently higher edge-detection precision and recall, improved lesion-state recall, and superior lesion-graph component F1 scores versus distance-only baselines.