Haoxuan Che

Haibo Jin, Haoxuan Che, Yi Lin et al.

Automatic medical report generation (MRG) is of great research value as it has the potential to relieve radiologists from the heavy burden of report writing. Despite recent advancements, accurate MRG remains challenging due to the need for precise clinical understanding and disease identification. Moreover, the imbalanced distribution of diseases makes the challenge even more pronounced, as rare diseases are underrepresented in training data, making their diagnostic performance unreliable. To address these challenges, we propose diagnosis-driven prompts for medical report generation (PromptMRG), a novel framework that aims to improve the diagnostic accuracy of MRG with the guidance of diagnosis-aware prompts. Specifically, PromptMRG is based on encoder-decoder architecture with an extra disease classification branch. When generating reports, the diagnostic results from the classification branch are converted into token prompts to explicitly guide the generation process. To further improve the diagnostic accuracy, we design cross-modal feature enhancement, which retrieves similar reports from the database to assist the diagnosis of a query image by leveraging the knowledge from a pre-trained CLIP. Moreover, the disease imbalanced issue is addressed by applying an adaptive logit-adjusted loss to the classification branch based on the individual learning status of each disease, which overcomes the barrier of text decoder's inability to manipulate disease distributions. Experiments on two MRG benchmarks show the effectiveness of the proposed method, where it obtains state-of-the-art clinical efficacy performance on both datasets. The code is available at https://github.com/jhb86253817/PromptMRG.

Haibo Jin, Haoxuan Che, Hao Chen

Recently, anatomical landmark detection has achieved great progresses on single-domain data, which usually assumes training and test sets are from the same domain. However, such an assumption is not always true in practice, which can cause significant performance drop due to domain shift. To tackle this problem, we propose a novel framework for anatomical landmark detection under the setting of unsupervised domain adaptation (UDA), which aims to transfer the knowledge from labeled source domain to unlabeled target domain. The framework leverages self-training and domain adversarial learning to address the domain gap during adaptation. Specifically, a self-training strategy is proposed to select reliable landmark-level pseudo-labels of target domain data with dynamic thresholds, which makes the adaptation more effective. Furthermore, a domain adversarial learning module is designed to handle the unaligned data distributions of two domains by learning domain-invariant features via adversarial training. Our experiments on cephalometric and lung landmark detection show the effectiveness of the method, which reduces the domain gap by a large margin and outperforms other UDA methods consistently. The code is available at https://github.com/jhb86253817/UDA_Med_Landmark.

Zhaoqing Li, Haoning Xu, Jingran Su et al.

We present UNISON, a latent diffusion framework that unifies speech generation, sound generation, and audio editing within a single model. A single model handles text-to-audio, text-to-speech, zero-shot speaker cloning, mixed speech-and-sound generation, scene-level audio editing, speech-in-scene editing, and timed temporal composition, all of which share a single set of weights. Our architecture features two core designs: (1) Layer-wise deep LLM fusion, which injects hidden states from uniformly sampled layers of a frozen MLLM into corresponding MM-DiT blocks via learned projections, providing depth-matched semantic conditioning that improves instruction following over single-layer baselines; and (2) a unified multi-task architecture where task identity is encoded solely by a channel-wise mask and source audio is provided through VAE-encoded channel concatenation. Training is stabilized by an online GPU-side multi-task data synthesis pipeline with task-homogeneous batching and a two-stage curriculum. With 621M--732M trainable parameters, UNISON achieves results competitive with or exceeding task-specialist models across evaluated domains, while being roughly $4\times$ smaller than comparable unified systems.

Bo Qian, Hao Chen, Xiangning Wang et al.

Computer-assisted automatic analysis of diabetic retinopathy (DR) is of great importance in reducing the risks of vision loss and even blindness. Ultra-wide optical coherence tomography angiography (UW-OCTA) is a non-invasive and safe imaging modality in DR diagnosis system, but there is a lack of publicly available benchmarks for model development and evaluation. To promote further research and scientific benchmarking for diabetic retinopathy analysis using UW-OCTA images, we organized a challenge named "DRAC - Diabetic Retinopathy Analysis Challenge" in conjunction with the 25th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2022). The challenge consists of three tasks: segmentation of DR lesions, image quality assessment and DR grading. The scientific community responded positively to the challenge, with 11, 12, and 13 teams from geographically diverse institutes submitting different solutions in these three tasks, respectively. This paper presents a summary and analysis of the top-performing solutions and results for each task of the challenge. The obtained results from top algorithms indicate the importance of data augmentation, model architecture and ensemble of networks in improving the performance of deep learning models. These findings have the potential to enable new developments in diabetic retinopathy analysis. The challenge remains open for post-challenge registrations and submissions for benchmarking future methodology developments.

Haoxuan Che, Yuhan Cheng, Haibo Jin et al.

Diabetic Retinopathy (DR) is a common complication of diabetes and a leading cause of blindness worldwide. Early and accurate grading of its severity is crucial for disease management. Although deep learning has shown great potential for automated DR grading, its real-world deployment is still challenging due to distribution shifts among source and target domains, known as the domain generalization problem. Existing works have mainly attributed the performance degradation to limited domain shifts caused by simple visual discrepancies, which cannot handle complex real-world scenarios. Instead, we present preliminary evidence suggesting the existence of three-fold generalization issues: visual and degradation style shifts, diagnostic pattern diversity, and data imbalance. To tackle these issues, we propose a novel unified framework named Generalizable Diabetic Retinopathy Grading Network (GDRNet). GDRNet consists of three vital components: fundus visual-artifact augmentation (FundusAug), dynamic hybrid-supervised loss (DahLoss), and domain-class-aware re-balancing (DCR). FundusAug generates realistic augmented images via visual transformation and image degradation, while DahLoss jointly leverages pixel-level consistency and image-level semantics to capture the diverse diagnostic patterns and build generalizable feature representations. Moreover, DCR mitigates the data imbalance from a domain-class view and avoids undesired over-emphasis on rare domain-class pairs. Finally, we design a publicly available benchmark for fair evaluations. Extensive comparison experiments against advanced methods and exhaustive ablation studies demonstrate the effectiveness and generalization ability of GDRNet.

Haoxuan Che, Haibo Jin, Hao Chen

Diabetic retinopathy (DR) and diabetic macular edema (DME) are leading causes of permanent blindness worldwide. Designing an automatic grading system with good generalization ability for DR and DME is vital in clinical practice. However, prior works either grade DR or DME independently, without considering internal correlations between them, or grade them jointly by shared feature representation, yet ignoring potential generalization issues caused by difficult samples and data bias. Aiming to address these problems, we propose a framework for joint grading with the dynamic difficulty-aware weighted loss (DAW) and the dual-stream disentangled learning architecture (DETACH). Inspired by curriculum learning, DAW learns from simple samples to difficult samples dynamically via measuring difficulty adaptively. DETACH separates features of grading tasks to avoid potential emphasis on the bias. With the addition of DAW and DETACH, the model learns robust disentangled feature representations to explore internal correlations between DR and DME and achieve better grading performance. Experiments on three benchmarks show the effectiveness and robustness of our framework under both the intra-dataset and cross-dataset tests.

Haoxuan Che, Siyu Chen, Hao Chen

Medical images usually suffer from image degradation in clinical practice, leading to decreased performance of deep learning-based models. To resolve this problem, most previous works have focused on filtering out degradation-causing low-quality images while ignoring their potential value for models. Through effectively learning and leveraging the knowledge of degradations, models can better resist their adverse effects and avoid misdiagnosis. In this paper, we raise the problem of image quality-aware diagnosis, which aims to take advantage of low-quality images and image quality labels to achieve a more accurate and robust diagnosis. However, the diversity of degradations and superficially unrelated targets between image quality assessment and disease diagnosis makes it still quite challenging to effectively leverage quality labels to assist diagnosis. Thus, to tackle these issues, we propose a novel meta-knowledge co-embedding network, consisting of two subnets: Task Net and Meta Learner. Task Net constructs an explicit quality information utilization mechanism to enhance diagnosis via knowledge co-embedding features, while Meta Learner ensures the effectiveness and constrains the semantics of these features via meta-learning and joint-encoding masking. Superior performance on five datasets with four widely-used medical imaging modalities demonstrates the effectiveness and generalizability of our method.

Weiwen Zhang, Dawei Yang, Haoxuan Che et al.

For optical coherence tomography angiography (OCTA) images, a limited scanning rate leads to a trade-off between field-of-view (FOV) and imaging resolution. Although larger FOV images may reveal more parafoveal vascular lesions, their application is greatly hampered due to lower resolution. To increase the resolution, previous works only achieved satisfactory performance by using paired data for training, but real-world applications are limited by the challenge of collecting large-scale paired images. Thus, an unpaired approach is highly demanded. Generative Adversarial Network (GAN) has been commonly used in the unpaired setting, but it may struggle to accurately preserve fine-grained capillary details, which are critical biomarkers for OCTA. In this paper, our approach aspires to preserve these details by leveraging the frequency information, which represents details as high-frequencies ($\textbf{hf}$) and coarse-grained backgrounds as low-frequencies ($\textbf{lf}$). In general, we propose a GAN-based unpaired super-resolution method for OCTA images and exceptionally emphasize $\textbf{hf}$ fine capillaries through a dual-path generator. To facilitate a precise spectrum of the reconstructed image, we also propose a frequency-aware adversarial loss for the discriminator and introduce a frequency-aware focal consistency loss for end-to-end optimization. Experiments show that our method outperforms other state-of-the-art unpaired methods both quantitatively and visually.

Zhefan Rao, Bin Zou, Haoxuan Che et al.

Instruction-based video editing is a natural way to control video content with text, but adapting a video generation model into an editor usually appears data-hungry. At the same time, high-quality video editing data remains scarce. In this paper, we show that a video generation backbone can become a strong video editor without large scale video editing data. We present InsEdit, an instruction-based editing model built on HunyuanVideo-1.5. InsEdit combines a visual editing architecture with a video data pipeline based on Mutual Context Attention (MCA), which creates aligned video pairs where edits can begin in the middle of a clip rather than only from the first frame. With only O(100)K video editing data, InsEdit achieves state-of-the-art results among open-source methods on our video instruction editing benchmarks. In addition, because our training recipe also includes image editing data, the final model supports image editing without any modification.

Yanbin Wei, Chun Kang, Siwei Li et al.

Large Vision-Language Models (LVLMs) consistently require new arenas to guide their expanding boundaries, yet their capabilities with hypergraphs remain unexplored. In the real world, hypergraphs have significant practical applications in areas such as life sciences and social communities. Recent advancements in LVLMs have shown promise in understanding complex topologies, yet there remains a lack of a benchmark to delineate the capabilities of LVLMs with hypergraphs, leaving the boundaries of their abilities unclear. To fill this gap, in this paper, we introduce $\texttt{HyperGVL}$, the first benchmark to evaluate the proficiency of LVLMs in hypergraph understanding and reasoning. $\texttt{HyperGVL}$ provides a comprehensive assessment of 12 advanced LVLMs across 84,000 vision-language question-answering (QA) samples spanning 12 tasks, ranging from basic component counting to complex NP-hard problem reasoning. The involved hypergraphs contain multiscale synthetic structures and real-world citation and protein networks. Moreover, we examine the effects of 12 textual and visual hypergraph representations and introduce a generalizable router $\texttt{WiseHyGR}$ that improves LVLMs in hypergraph via learning adaptive representations. We believe that this work is a step forward in connecting hypergraphs with LVLMs.

Haibo Jin, Haoxuan Che, Hao Chen

Self-training is a simple yet effective method for semi-supervised learning, during which pseudo-label selection plays an important role for handling confirmation bias. Despite its popularity, applying self-training to landmark detection faces three problems: 1) The selected confident pseudo-labels often contain data bias, which may hurt model performance; 2) It is not easy to decide a proper threshold for sample selection as the localization task can be sensitive to noisy pseudo-labels; 3) coordinate regression does not output confidence, making selection-based self-training infeasible. To address the above issues, we propose Self-Training for Landmark Detection (STLD), a method that does not require explicit pseudo-label selection. Instead, STLD constructs a task curriculum to deal with confirmation bias, which progressively transitions from more confident to less confident tasks over the rounds of self-training. Pseudo pretraining and shrink regression are two essential components for such a curriculum, where the former is the first task of the curriculum for providing a better model initialization and the latter is further added in the later rounds to directly leverage the pseudo-labels in a coarse-to-fine manner. Experiments on three facial and one medical landmark detection benchmark show that STLD outperforms the existing methods consistently in both semi- and omni-supervised settings. The code is available at https://github.com/jhb86253817/STLD.

Meng Chu, Senqiao Yang, Haoxuan Che et al.

Generative models can now produce photorealistic imagery, yet they still struggle with the long, multi-goal prompts that professional designers issue. To expose this gap and better evaluate models' performance in real-world settings, we introduce Long Goal Bench (LGBench), a 2,000-task suite (1,000 T2I and 1,000 I2I) whose average instruction contains 18 to 22 tightly coupled goals spanning global layout, local object placement, typography, and logo fidelity. We find that even state-of-the-art models satisfy fewer than 72 percent of the goals and routinely miss localized edits, confirming the brittleness of current pipelines. To address this, we present VisionDirector, a training-free vision-language supervisor that (i) extracts structured goals from long instructions, (ii) dynamically decides between one-shot generation and staged edits, (iii) runs micro-grid sampling with semantic verification and rollback after every edit, and (iv) logs goal-level rewards. We further fine-tune the planner with Group Relative Policy Optimization, yielding shorter edit trajectories (3.1 versus 4.2 steps) and stronger alignment. VisionDirector achieves new state of the art on GenEval (plus 7 percent overall) and ImgEdit (plus 0.07 absolute) while producing consistent qualitative improvements on typography, multi-object scenes, and pose editing.

Yaofang Liu, Kangning Cui, Meng Chu et al.

Humans often specify and create through visual artifacts: typography sheets, sketches, reference images, and annotated scenes. Yet modern visual generators still ask users to serialize this intent into text, a bottleneck that compresses signals like spatial structure, exact appearance, and glyph shape. We propose \textbf{\emph{visual-to-visual} (V2V)} generation, in which the user conditions a generative model with a visual specification page rather than a text prompt. The page is not an edit target, but a visual document that specifies the desired output. We introduce \textbf{V2V-Zero}, a training-free framework that exposes this interface in existing vision-language model (VLM) conditioned generators by replacing text-only conditioning with final-layer hidden states extracted from visual pages, exploiting the fact that the frozen VLM already maps both text and images into the generator's conditioning space. On GenEval, V2V-Zero reaches 0.85 with a frozen Qwen-Image backbone, closely matching its optimized text-to-image performance without fine-tuning. To evaluate the broader V2V space, we introduce \textbf{Simple-V2V Bench}, spanning seven visual-conditioning tasks and seven models, including GPT Image 2, Nano Banana 2, Seedream 5.0 Lite, open-weight baselines, and a video extension. V2V-Zero scores 32.7/100, outperforming evaluated open-weight image baselines and revealing a clear capability hierarchy: attribute binding is strong, content generation is unreliable, and structural control remains hard even for commercial systems. A HunyuanVideo-1.5 extension scores 20.2/100, showing the interface transfers beyond images. Mechanistic analysis shows the default reasoning path is primarily visually routed, with 95.0\% of conditioning-token attention mass on visual-page hidden states.

Haoxuan Che, Xuanhua He, Quande Liu et al.

We introduce GameGen-X, the first diffusion transformer model specifically designed for both generating and interactively controlling open-world game videos. This model facilitates high-quality, open-domain generation by simulating an extensive array of game engine features, such as innovative characters, dynamic environments, complex actions, and diverse events. Additionally, it provides interactive controllability, predicting and altering future content based on the current clip, thus allowing for gameplay simulation. To realize this vision, we first collected and built an Open-World Video Game Dataset from scratch. It is the first and largest dataset for open-world game video generation and control, which comprises over a million diverse gameplay video clips sampling from over 150 games with informative captions from GPT-4o. GameGen-X undergoes a two-stage training process, consisting of foundation model pre-training and instruction tuning. Firstly, the model was pre-trained via text-to-video generation and video continuation, endowing it with the capability for long-sequence, high-quality open-domain game video generation. Further, to achieve interactive controllability, we designed InstructNet to incorporate game-related multi-modal control signal experts. This allows the model to adjust latent representations based on user inputs, unifying character interaction and scene content control for the first time in video generation. During instruction tuning, only the InstructNet is updated while the pre-trained foundation model is frozen, enabling the integration of interactive controllability without loss of diversity and quality of generated video content.

Meng Chu, Xuan Billy Zhang, Kevin Qinghong Lin et al.

As AI systems move from generating text to accomplishing goals through sustained interaction, the ability to model environment dynamics becomes a central bottleneck. Agents that manipulate objects, navigate software, coordinate with others, or design experiments require predictive environment models, yet the term world model carries different meanings across research communities. We introduce a "levels x laws" taxonomy organized along two axes. The first defines three capability levels: L1 Predictor, which learns one-step local transition operators; L2 Simulator, which composes them into multi-step, action-conditioned rollouts that respect domain laws; and L3 Evolver, which autonomously revises its own model when predictions fail against new evidence. The second identifies four governing-law regimes: physical, digital, social, and scientific. These regimes determine what constraints a world model must satisfy and where it is most likely to fail. Using this framework, we synthesize over 400 works and summarize more than 100 representative systems spanning model-based reinforcement learning, video generation, web and GUI agents, multi-agent social simulation, and AI-driven scientific discovery. We analyze methods, failure modes, and evaluation practices across level-regime pairs, propose decision-centric evaluation principles and a minimal reproducible evaluation package, and outline architectural guidance, open problems, and governance challenges. The resulting roadmap connects previously isolated communities and charts a path from passive next-step prediction toward world models that can simulate, and ultimately reshape, the environments in which agents operate.

Jiwen Yu, Yiran Qin, Haoxuan Che et al.

Interactive Generative Video (IGV) has emerged as a crucial technology in response to the growing demand for high-quality, interactive video content across various domains. In this paper, we define IGV as a technology that combines generative capabilities to produce diverse high-quality video content with interactive features that enable user engagement through control signals and responsive feedback. We survey the current landscape of IGV applications, focusing on three major domains: 1) gaming, where IGV enables infinite exploration in virtual worlds; 2) embodied AI, where IGV serves as a physics-aware environment synthesizer for training agents in multimodal interaction with dynamically evolving scenes; and 3) autonomous driving, where IGV provides closed-loop simulation capabilities for safety-critical testing and validation. To guide future development, we propose a comprehensive framework that decomposes an ideal IGV system into five essential modules: Generation, Control, Memory, Dynamics, and Intelligence. Furthermore, we systematically analyze the technical challenges and future directions in realizing each component for an ideal IGV system, such as achieving real-time generation, enabling open-domain control, maintaining long-term coherence, simulating accurate physics, and integrating causal reasoning. We believe that this systematic analysis will facilitate future research and development in the field of IGV, ultimately advancing the technology toward more sophisticated and practical applications.

Zhihan Xiao, Lin Liu, Yixin Gao et al.

Text-guided video editing, particularly for object removal and addition, remains a challenging task due to the need for precise spatial and temporal consistency. Existing methods often rely on auxiliary masks or reference images for editing guidance, which limits their scalability and generalization. To address these issues, we propose LoVoRA, a novel framework for mask-free video object removal and addition using object-aware localization mechanism. Our approach utilizes a unique dataset construction pipeline that integrates image-to-video translation, optical flow-based mask propagation, and video inpainting, enabling temporally consistent edits. The core innovation of LoVoRA is its learnable object-aware localization mechanism, which provides dense spatio-temporal supervision for both object insertion and removal tasks. By leveraging a Diffusion Mask Predictor, LoVoRA achieves end-to-end video editing without requiring external control signals during inference. Extensive experiments and human evaluation demonstrate the effectiveness and high-quality performance of LoVoRA. https://cz-5f.github.io/LoVoRA.github.io

Jiwen Yu, Yiran Qin, Haoxuan Che et al.

Modern game development faces significant challenges in creativity and cost due to predetermined content in traditional game engines. Recent breakthroughs in video generation models, capable of synthesizing realistic and interactive virtual environments, present an opportunity to revolutionize game creation. In this position paper, we propose Interactive Generative Video (IGV) as the foundation for Generative Game Engines (GGE), enabling unlimited novel content generation in next-generation gaming. GGE leverages IGV's unique strengths in unlimited high-quality content synthesis, physics-aware world modeling, user-controlled interactivity, long-term memory capabilities, and causal reasoning. We present a comprehensive framework detailing GGE's core modules and a hierarchical maturity roadmap (L0-L4) to guide its evolution. Our work charts a new course for game development in the AI era, envisioning a future where AI-powered generative systems fundamentally reshape how games are created and experienced.

Haoxuan Che, Haibo Jin, Zhengrui Guo et al.

LLMs have demonstrated significant potential in Medical Report Generation (MRG), yet their development requires large amounts of medical image-report pairs, which are commonly scattered across multiple centers. Centralizing these data is exceptionally challenging due to privacy regulations, thereby impeding model development and broader adoption of LLM-driven MRG models. To address this challenge, we present FedMRG, the first framework that leverages Federated Learning (FL) to enable privacy-preserving, multi-center development of LLM-driven MRG models, specifically designed to overcome the critical challenge of communication-efficient LLM training under multi-modal data heterogeneity. To start with, our framework tackles the fundamental challenge of communication overhead in FL-LLM tuning by employing low-rank factorization to efficiently decompose parameter updates, significantly reducing gradient transmission costs and making LLM-driven MRG feasible in bandwidth-constrained FL settings. Furthermore, we observed the dual heterogeneity in MRG under the FL scenario: varying image characteristics across medical centers, as well as diverse reporting styles and terminology preferences. To address this, we further enhance FedMRG with (1) client-aware contrastive learning in the MRG encoder, coupled with diagnosis-driven prompts, which capture both globally generalizable and locally distinctive features while maintaining diagnostic accuracy; and (2) a dual-adapter mutual boosting mechanism in the MRG decoder that harmonizes generic and specialized adapters to address variations in reporting styles and terminology. Through extensive evaluation of our established FL-MRG benchmark, we demonstrate the generalizability and adaptability of FedMRG, underscoring its potential in harnessing multi-center data and generating clinically accurate reports while maintaining communication efficiency.

Haoxuan Che, Yifei Wu, Haibo Jin et al.

Federated domain generalization aims to train a global model from multiple source domains and ensure its generalization ability to unseen target domains. Due to the target domain being with unknown domain shifts, attempting to approximate these gaps by source domains may be the key to improving model generalization capability. Existing works mainly focus on sharing and recombining local domain-specific attributes to increase data diversity and simulate potential domain shifts. However, these methods may be insufficient since only the local attribute recombination can be hard to touch the out-of-distribution of global data. In this paper, we propose a simple-yet-efficient framework named Federated Domain Adversarial Generation (FedDAG). It aims to simulate the domain shift and improve the model generalization by adversarially generating novel domains different from local and global source domains. Specifically, it generates novel-style images by maximizing the instance-level feature discrepancy between original and generated images and trains a generalizable task model by minimizing their feature discrepancy. Further, we observed that FedDAG could cause different performance improvements for local models. It may be due to inherent data isolation and heterogeneity among clients, exacerbating the imbalance in their generalization contributions to the global model. Ignoring this imbalance can lead the global model's generalization ability to be sub-optimal, further limiting the novel domain generation procedure. Thus, to mitigate this imbalance, FedDAG hierarchically aggregates local models at the within-client and across-client levels by using the sharpness concept to evaluate client model generalization contributions. Extensive experiments across four medical benchmarks demonstrate FedDAG's ability to enhance generalization in federated medical scenarios.

Haibo Jin, Haoxuan Che, Sunan He et al.

Despite the progress of radiology report generation (RRG), existing works face two challenges: 1) The performances in clinical efficacy are unsatisfactory, especially for lesion attributes description; 2) the generated text lacks explainability, making it difficult for radiologists to trust the results. To address the challenges, we focus on a trustworthy RRG model, which not only generates accurate descriptions of abnormalities, but also provides basis of its predictions. To this end, we propose a framework named chain of diagnosis (CoD), which maintains a chain of diagnostic process for clinically accurate and explainable RRG. It first generates question-answer (QA) pairs via diagnostic conversation to extract key findings, then prompts a large language model with QA diagnoses for accurate generation. To enhance explainability, a diagnosis grounding module is designed to match QA diagnoses and generated sentences, where the diagnoses act as a reference. Moreover, a lesion grounding module is designed to locate abnormalities in the image, further improving the working efficiency of radiologists. To facilitate label-efficient training, we propose an omni-supervised learning strategy with clinical consistency to leverage various types of annotations from different datasets. Our efforts lead to 1) an omni-labeled RRG dataset with QA pairs and lesion boxes; 2) a evaluation tool for assessing the accuracy of reports in describing lesion location and severity; 3) extensive experiments to demonstrate the effectiveness of CoD, where it outperforms both specialist and generalist models consistently on two RRG benchmarks and shows promising explainability by accurately grounding generated sentences to QA diagnoses and images.

Yingying Wang, Xuanhua He, Chen Wu et al.

Pan-sharpening aims to generate high-resolution multispectral (HRMS) images by integrating a high-resolution panchromatic (PAN) image with its corresponding low-resolution multispectral (MS) image. To achieve effective fusion, it is crucial to fully exploit the complementary information between the two modalities. Traditional CNN-based methods typically rely on channel-wise concatenation with fixed convolutional operators, which limits their adaptability to diverse spatial and spectral variations. While cross-attention mechanisms enable global interactions, they are computationally inefficient and may dilute fine-grained correspondences, making it difficult to capture complex semantic relationships. Recent advances in the Multimodal Diffusion Transformer (MMDiT) architecture have demonstrated impressive success in image generation and editing tasks. Unlike cross-attention, MMDiT employs in-context conditioning to facilitate more direct and efficient cross-modal information exchange. In this paper, we propose MMMamba, a cross-modal in-context fusion framework for pan-sharpening, with the flexibility to support image super-resolution in a zero-shot manner. Built upon the Mamba architecture, our design ensures linear computational complexity while maintaining strong cross-modal interaction capacity. Furthermore, we introduce a novel multimodal interleaved (MI) scanning mechanism that facilitates effective information exchange between the PAN and MS modalities. Extensive experiments demonstrate the superior performance of our method compared to existing state-of-the-art (SOTA) techniques across multiple tasks and benchmarks.