Yuxiang Nie

Yuxiang Nie, Heyan Huang, Wei Wei et al. · microsoft-research

Long document question answering is a challenging task due to its demands for complex reasoning over long text. Previous works usually take long documents as non-structured flat texts or only consider the local structure in long documents. However, these methods usually ignore the global structure of the long document, which is essential for long-range understanding. To tackle this problem, we propose Compressive Graph Selector Network (CGSN) to capture the global structure in a compressive and iterative manner. The proposed model mainly focuses on the evidence selection phase of long document question answering. Specifically, it consists of three modules: local graph network, global graph network and evidence memory network. Firstly, the local graph network builds the graph structure of the chunked segment in token, sentence, paragraph and segment levels to capture the short-term dependency of the text. Secondly, the global graph network selectively receives the information of each level from the local graph, compresses them into the global graph nodes and applies graph attention to the global graph nodes to build the long-range reasoning over the entire text in an iterative way. Thirdly, the evidence memory network is designed to alleviate the redundancy problem in the evidence selection by saving the selected result in the previous steps. Extensive experiments show that the proposed model outperforms previous methods on two datasets.

Yuxiang Nie, Heyan Huang, Zewen Chi et al.

Unsupervised question answering is an attractive task due to its independence on labeled data. Previous works usually make use of heuristic rules as well as pre-trained models to construct data and train QA models. However, most of these works regard named entity (NE) as the only answer type, which ignores the high diversity of answers in the real world. To tackle this problem, we propose a novel unsupervised method by diversifying answers, named DiverseQA. Specifically, the proposed method is composed of three modules: data construction, data augmentation and denoising filter. Firstly, the data construction module extends the extracted named entity into a longer sentence constituent as the new answer span to construct a QA dataset with diverse answers. Secondly, the data augmentation module adopts an answer-type dependent data augmentation process via adversarial training in the embedding level. Thirdly, the denoising filter module is designed to alleviate the noise in the constructed data. Extensive experiments show that the proposed method outperforms previous unsupervised models on five benchmark datasets, including SQuADv1.1, NewsQA, TriviaQA, BioASQ, and DuoRC. Besides, the proposed method shows strong performance in the few-shot learning setting.

Xiao Zhang, Heqi Zheng, Yuxiang Nie et al.

Scientific machine reading comprehension (SMRC) aims to understand scientific texts through interactions with humans by given questions. As far as we know, there is only one dataset focused on exploring full-text scientific machine reading comprehension. However, the dataset has ignored the fact that different readers may have different levels of understanding of the text, and only includes single-perspective question-answer pairs, leading to a lack of consideration of different perspectives. To tackle the above problem, we propose a novel multi-perspective SMRC dataset, called SciMRC, which includes perspectives from beginners, students and experts. Our proposed SciMRC is constructed from 741 scientific papers and 6,057 question-answer pairs. Each perspective of beginners, students and experts contains 3,306, 1,800 and 951 QA pairs, respectively. The extensive experiments on SciMRC by utilizing pre-trained models suggest the importance of considering perspectives of SMRC, and demonstrate its challenging nature for machine comprehension.

Yuting He, Fuxiang Huang, Xinrui Jiang et al.

Foundation model, which is pre-trained on broad data and is able to adapt to a wide range of tasks, is advancing healthcare. It promotes the development of healthcare artificial intelligence (AI) models, breaking the contradiction between limited AI models and diverse healthcare practices. Much more widespread healthcare scenarios will benefit from the development of a healthcare foundation model (HFM), improving their advanced intelligent healthcare services. Despite the impending widespread deployment of HFMs, there is currently a lack of clear understanding about how they work in the healthcare field, their current challenges, and where they are headed in the future. To answer these questions, a comprehensive and deep survey of the challenges, opportunities, and future directions of HFMs is presented in this survey. It first conducted a comprehensive overview of the HFM including the methods, data, and applications for a quick grasp of the current progress. Then, it made an in-depth exploration of the challenges present in data, algorithms, and computing infrastructures for constructing and widespread application of foundation models in healthcare. This survey also identifies emerging and promising directions in this field for future development. We believe that this survey will enhance the community's comprehension of the current progress of HFM and serve as a valuable source of guidance for future development in this field. The latest HFM papers and related resources are maintained on our website: https://github.com/YutingHe-list/Awesome-Foundation-Models-for-Advancing-Healthcare.

Han Wang, Yanjie Wang, Yongjie Ye et al.

Multi-modal Large Language Models (MLLMs) have demonstrated their ability to perceive objects in still images, but their application in video-related tasks, such as object tracking, remains understudied. This lack of exploration is primarily due to two key challenges. Firstly, extensive pretraining on large-scale video datasets is required to equip MLLMs with the capability to perceive objects across multiple frames and understand inter-frame relationships. Secondly, processing a large number of frames within the context window of Large Language Models (LLMs) can impose a significant computational burden. To address the first challenge, we introduce ElysiumTrack-1M, a large-scale video dataset supported for three tasks: Single Object Tracking (SOT), Referring Single Object Tracking (RSOT), and Video Referring Expression Generation (Video-REG). ElysiumTrack-1M contains 1.27 million annotated video frames with corresponding object boxes and descriptions. Leveraging this dataset, we conduct training of MLLMs and propose a token-compression model T-Selector to tackle the second challenge. Our proposed approach, Elysium: Exploring Object-level Perception in Videos via MLLM, is an end-to-end trainable MLLM that attempts to conduct object-level tasks in videos without requiring any additional plug-in or expert models. All codes and datasets are available at https://github.com/Hon-Wong/Elysium.

Sunan He, Yuxiang Nie, Hongmei Wang et al.

Generalist foundation models (GFMs) are renowned for their exceptional capability and flexibility in effectively generalizing across diverse tasks and modalities. In the field of medicine, while GFMs exhibit superior generalizability based on their extensive intrinsic knowledge as well as proficiency in instruction following and in-context learning, specialist models excel in precision due to their domain knowledge. In this work, for the first time, we explore the synergy between the GFM and specialist models, to enable precise medical image analysis on a broader scope. Specifically, we propose a cooperative framework, Generalist-Specialist Collaboration (GSCo), which consists of two stages, namely the construction of GFM and specialists, and collaborative inference on downstream tasks. In the construction stage, we develop MedDr, the largest open-source GFM tailored for medicine, showcasing exceptional instruction-following and in-context learning capabilities. Meanwhile, a series of lightweight specialists are crafted for downstream tasks with low computational cost. In the collaborative inference stage, we introduce two cooperative mechanisms, Mixture-of-Expert Diagnosis and Retrieval-Augmented Diagnosis, to harvest the generalist's in-context learning abilities alongside the specialists' domain expertise. For a comprehensive evaluation, we curate a large-scale benchmark featuring 28 datasets and about 250,000 images. Extensive results demonstrate that MedDr consistently outperforms state-of-the-art GFMs on downstream datasets. Furthermore, GSCo exceeds both GFMs and specialists across all out-of-domain disease diagnosis datasets. These findings indicate a significant paradigm shift in the application of GFMs, transitioning from separate models for specific tasks to a collaborative approach between GFMs and specialists, thereby advancing the frontiers of generalizable AI in medicine.

Han Wang, Yuxiang Nie, Yongjie Ye et al.

The application of Large Vision-Language Models (LVLMs) for analyzing images and videos is an exciting and rapidly evolving field. In recent years, we've seen significant growth in high-quality image-text datasets for fine-tuning image understanding, but there is still a lack of comparable datasets for videos. Additionally, many VideoLLMs are extensions of single-image VLMs, which may not efficiently handle the complexities of longer videos. In this study, we introduce a large-scale synthetic dataset created from proprietary models, using carefully designed prompts to tackle a wide range of questions. We also explore a dynamic visual token compression architecture that strikes a balance between computational efficiency and performance. Our proposed \model{} achieves state-of-the-art results across various video tasks and shows impressive generalization, setting new baselines in multi-image understanding. Notably, \model{} delivers an absolute improvement of 2.7\% over LLaVA-OneVision on VideoMME and 10.7\% on MuirBench. Codes are available at https://github.com/Hon-Wong/ByteVideoLLM

Han Wang, Yongjie Ye, Bingru Li et al.

We introduce Vision as LoRA (VoRA), a novel paradigm for transforming an LLM into an MLLM. Unlike prevalent MLLM architectures that rely on external vision modules for vision encoding, VoRA internalizes visual capabilities by integrating vision-specific LoRA layers directly into the LLM. This design allows the added parameters to be seamlessly merged into the LLM during inference, eliminating structural complexity and minimizing computational overhead. Moreover, inheriting the LLM's ability of handling flexible context, VoRA can process inputs at arbitrary resolutions. To further strengthen VoRA's visual capabilities, we introduce a block-wise distillation method that transfers visual priors from a pre-trained ViT into the LoRA layers, effectively accelerating training by injecting visual knowledge. Additionally, we apply bi-directional attention masks to better capture the context information of an image. We successfully demonstrate that with additional pre-training data, VoRA can perform comparably with conventional encode-based MLLMs. All training data, codes, and model weights will be released at https://github.com/Hon-Wong/VoRA.

Yuxiang Nie, Han Wang, Yongjie Ye et al.

This paper introduces ChineseVideoBench, a pioneering benchmark specifically designed for evaluating Multimodal Large Language Models (MLLMs) in Chinese Video Question Answering. The growing demand for sophisticated video analysis capabilities highlights the critical need for comprehensive, culturally-aware evaluation frameworks. ChineseVideoBench addresses this gap by providing a robust dataset and tailored evaluation metrics, enabling rigorous assessment of state-of-the-art MLLMs on complex Chinese video content. Specifically, ChineseVideoBench comprises 8 main classes and 12 sub-classes, encompassing tasks that demand both deep video understanding and nuanced Chinese linguistic and cultural awareness. Our empirical evaluations reveal that ChineseVideoBench presents a significant challenge to current MLLMs. Among the models assessed, Gemini 2.5 Pro achieves the highest performance with an overall score of 77.9%, while InternVL-38B emerges as the most competitive open-source model.

Sau Lai Yip, Sunan He, Yuxiang Nie et al.

The accelerating development of general medical artificial intelligence (GMAI), powered by multimodal large language models (MLLMs), offers transformative potential for addressing persistent healthcare challenges, including workforce deficits and escalating costs. The parallel development of systematic evaluation benchmarks emerges as a critical imperative to enable performance assessment and provide technological guidance. Meanwhile, as an invaluable knowledge source, the potential of medical textbooks for benchmark development remains underexploited. Here, we present MedBookVQA, a systematic and comprehensive multimodal benchmark derived from open-access medical textbooks. To curate this benchmark, we propose a standardized pipeline for automated extraction of medical figures while contextually aligning them with corresponding medical narratives. Based on this curated data, we generate 5,000 clinically relevant questions spanning modality recognition, disease classification, anatomical identification, symptom diagnosis, and surgical procedures. A multi-tier annotation system categorizes queries through hierarchical taxonomies encompassing medical imaging modalities (42 categories), body anatomies (125 structures), and clinical specialties (31 departments), enabling nuanced analysis across medical subdomains. We evaluate a wide array of MLLMs, including proprietary, open-sourced, medical, and reasoning models, revealing significant performance disparities across task types and model categories. Our findings highlight critical capability gaps in current GMAI systems while establishing textbook-derived multimodal benchmarks as essential evaluation tools. MedBookVQA establishes textbook-derived benchmarking as a critical paradigm for advancing clinical AI, exposing limitations in GMAI systems while providing anatomically structured performance metrics across specialties.

Shu Yang, Fengtao Zhou, Leon Mayer et al.

Computer-Assisted Intervention (CAI) has the potential to revolutionize modern surgery, with surgical scene understanding serving as a critical component in supporting decision-making, improving procedural efficacy, and ensuring intraoperative safety. While existing AI-driven approaches alleviate annotation burdens via self-supervised spatial representation learning, their lack of explicit temporal modeling during pre-training fundamentally restricts the capture of dynamic surgical contexts, resulting in incomplete spatiotemporal understanding. In this work, we introduce the first video-level surgical pre-training framework that enables joint spatiotemporal representation learning from large-scale surgical video data. To achieve this, we constructed a large-scale surgical video dataset comprising 3,650 videos and approximately 3.55 million frames, spanning more than 20 surgical procedures and over 10 anatomical structures. Building upon this dataset, we propose SurgVISTA (Surgical Video-level Spatial-Temporal Architecture), a reconstruction-based pre-training method that captures intricate spatial structures and temporal dynamics through joint spatiotemporal modeling. Additionally, SurgVISTA incorporates image-level knowledge distillation guided by a surgery-specific expert to enhance the learning of fine-grained anatomical and semantic features. To validate its effectiveness, we established a comprehensive benchmark comprising 13 video-level datasets spanning six surgical procedures across four tasks. Extensive experiments demonstrate that SurgVISTA consistently outperforms both natural- and surgical-domain pre-trained models, demonstrating strong potential to advance intelligent surgical systems in clinically meaningful scenarios.

Yuxiang Nie, Sunan He, Yequan Bie et al.

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance, their black-box nature hinders explaining the decision-making process in clinically meaningful concepts. Here, we present ConceptCLIP, the first explainable biomedical foundation model that achieves state-of-the-art diagnostic accuracy while delivering human-interpretable explanations across diverse imaging modalities. We curate MedConcept-23M, the largest pre-training dataset comprising 23 million image-text-concept triplets across diverse medical modalities, where clinical concepts are derived from the Unified Medical Language System. Leveraging this dataset, we develop ConceptCLIP through a novel dual-alignment approach that simultaneously learns global image-text representations and fine-grained region-concept associations for precise and interpretable medical image analysis. We curate the most extensive evaluation benchmark for multimodal biomedical foundation models, covering 52 clinical tasks spanning 10 imaging modalities. Extensive experiments demonstrate that ConceptCLIP outperforms existing state-of-the-art multimodal biomedical foundation models. Importantly, ConceptCLIP demonstrates superior diagnostic performance while providing human-understandable explanations validated by clinical experts. As the first precise and interpretable biomedical foundation model, ConceptCLIP represents a critical milestone toward the widespread clinical adoption of AI, thereby advancing trustworthy AI in medicine.

Linshan Wu, Yuxiang Nie, Sunan He et al.

The integration of AI-assisted biomedical image analysis into clinical practice demands AI-generated findings that are not only accurate but also interpretable to clinicians. However, existing biomedical AI models generally lack the ability to simultaneously generate diagnostic findings and localize corresponding biomedical objects. This limitation makes it challenging for clinicians to correlate AI-generated findings with visual evidence (e.g., tiny lesions) in images and interpret the results of AI models. To address this challenge, we introduce UniBiomed, the first universal foundation model for grounded biomedical image interpretation, which is capable of generating accurate diagnostic findings and simultaneously segmenting the corresponding biomedical targets. UniBiomed is based on a novel integration of Multi-modal Large Language Model and Segment Anything Model, which can effectively unify diverse biomedical tasks in universal training for advancing grounded interpretation. To develop UniBiomed, we curate a large-scale dataset comprising over 27 million triplets of images, region annotations, and text descriptions across ten biomedical imaging modalities. Extensive validation on 70 internal and 14 external datasets demonstrated the state-of-the-art performance of UniBiomed in diverse biomedical tasks, including image segmentation, disease recognition, region-aware diagnosis, vision question answering, and report generation. In summary, UniBiomed is a powerful and versatile biomedical foundation model, unlocking the untapped grounded interpretation capability for optimizing AI-assisted biomedical image analysis.

Yuxiang Nie, Heyan Huang, Xian-Ling Mao et al.

Mixed initiative serves as one of the key factors in controlling conversation directions. For a speaker, responding passively or leading proactively would result in rather different responses. However, most dialogue systems focus on training a holistic response generation model without any distinction among different initiatives. It leads to the cross-contamination problem, where the model confuses different initiatives and generates inappropriate responses. Moreover, obtaining plenty of human annotations for initiative labels can be expensive. To address this issue, we propose a general mix-Initiative Dynamic Prefix Tuning framework (IDPT) to decouple different initiatives from the generation model, which learns initiative-aware prefixes in both supervised and unsupervised settings. Specifically, IDPT decouples initiative factors into different prefix parameters and uses the attention mechanism to adjust the selection of initiatives in guiding generation dynamically. The prefix parameters can be tuned towards accurate initiative prediction as well as mix-initiative response generation. Extensive experiments on two public dialogue datasets show that the proposed IDPT outperforms previous baselines on both automatic metrics and human evaluations. It also manages to generate appropriate responses with manipulated initiatives.

Weitao Jia, Jinghui Lu, Haiyang Yu et al.

Recent advances demonstrate that reinforcement learning with verifiable rewards (RLVR) significantly enhances the reasoning capabilities of large language models (LLMs). However, standard RLVR faces challenges with reward sparsity, where zero rewards from consistently incorrect candidate answers provide no learning signal, particularly in challenging tasks. To address this, we propose Multi-Expert Mutual Learning GRPO (MEML-GRPO), an innovative framework that utilizes diverse expert prompts as system prompts to generate a broader range of responses, substantially increasing the likelihood of identifying correct solutions. Additionally, we introduce an inter-expert mutual learning mechanism that facilitates knowledge sharing and transfer among experts, further boosting the model's performance through RLVR. Extensive experiments across multiple reasoning benchmarks show that MEML-GRPO delivers significant improvements, achieving an average performance gain of 4.89% with Qwen and 11.33% with Llama, effectively overcoming the core limitations of traditional RLVR methods.

Xiang Fei, Siqi Wang, Shu Wei et al.

Current language model training paradigms typically terminate learning upon reaching the end-of-sequence (<eos>) token, overlooking the potential learning opportunities in the post-completion space. We propose Post-Completion Learning (PCL), a novel training framework that systematically utilizes the sequence space after model output completion, to enhance both the reasoning and self-evaluation abilities. PCL enables models to continue generating self-assessments and reward predictions during training, while maintaining efficient inference by stopping at the completion point. To fully utilize this post-completion space, we design a white-box reinforcement learning method: let the model evaluate the output content according to the reward rules, then calculate and align the score with the reward functions for supervision. We implement dual-track SFT to optimize both reasoning and evaluation capabilities, and mixed it with RL training to achieve multi-objective hybrid optimization. Experimental results on different datasets and models demonstrate consistent improvements over traditional SFT and RL methods. Our method provides a new technical path for language model training that enhances output quality while preserving deployment efficiency.

Yuxiang Nie, Heyan Huang, Wei Wei et al.

Annotating long-document question answering (long-document QA) pairs is time-consuming and expensive. To alleviate the problem, it might be possible to generate long-document QA pairs via unsupervised question answering (UQA) methods. However, existing UQA tasks are based on short documents, and can hardly incorporate long-range information. To tackle the problem, we propose a new task, named unsupervised long-document question answering (ULQA), aiming to generate high-quality long-document QA instances in an unsupervised manner. Besides, we propose AttenWalker, a novel unsupervised method to aggregate and generate answers with long-range dependency so as to construct long-document QA pairs. Specifically, AttenWalker is composed of three modules, i.e., span collector, span linker and answer aggregator. Firstly, the span collector takes advantage of constituent parsing and reconstruction loss to select informative candidate spans for constructing answers. Secondly, by going through the attention graph of a pre-trained long-document model, potentially interrelated text spans (that might be far apart) could be linked together via an attention-walking algorithm. Thirdly, in the answer aggregator, linked spans are aggregated into the final answer via the mask-filling ability of a pre-trained model. Extensive experiments show that AttenWalker outperforms previous methods on Qasper and NarrativeQA. In addition, AttenWalker also shows strong performance in the few-shot learning setting.

Yong Hu, Heyan Huang, Tian Lan et al.

Second language acquisition (SLA) modeling is to predict whether second language learners could correctly answer the questions according to what they have learned. It is a fundamental building block of the personalized learning system and has attracted more and more attention recently. However, as far as we know, almost all existing methods cannot work well in low-resource scenarios due to lacking of training data. Fortunately, there are some latent common patterns among different language-learning tasks, which gives us an opportunity to solve the low-resource SLA modeling problem. Inspired by this idea, in this paper, we propose a novel SLA modeling method, which learns the latent common patterns among different language-learning datasets by multi-task learning and are further applied to improving the prediction performance in low-resource scenarios. Extensive experiments show that the proposed method performs much better than the state-of-the-art baselines in the low-resource scenario. Meanwhile, it also obtains improvement slightly in the non-low-resource scenario.