Yi Qin

Kabir Hamzah Muhammad, Marawan Elbatel, Yi Qin et al.

Cardiovascular diseases (CVDs) remain the leading cause of mortality globally, and echocardiography is critical for diagnosis of both common and congenital cardiac conditions. However, echocardiographic data for certain pathologies are scarce, hindering the development of robust automated diagnosis models. In this work, we propose Echo-Path, a novel generative framework to produce echocardiogram videos conditioned on specific cardiac pathologies. Echo-Path can synthesize realistic ultrasound video sequences that exhibit targeted abnormalities, focusing here on atrial septal defect (ASD) and pulmonary arterial hypertension (PAH). Our approach introduces a pathology-conditioning mechanism into a state-of-the-art echo video generator, allowing the model to learn and control disease-specific structural and motion patterns in the heart. Quantitative evaluation demonstrates that the synthetic videos achieve low distribution distances, indicating high visual fidelity. Clinically, the generated echoes exhibit plausible pathology markers. Furthermore, classifiers trained on our synthetic data generalize well to real data and, when used to augment real training sets, it improves downstream diagnosis of ASD and PAH by 7\% and 8\% respectively. Code, weights and dataset are available here https://github.com/Marshall-mk/EchoPathv1

Xinyue Xu, Yueying Hu, Hui Tang et al.

Concept Bottleneck Models (CBMs) enhance interpretability by explaining predictions through human-understandable concepts but typically assume that training and test data share the same distribution. This assumption often fails under domain shifts, leading to degraded performance and poor generalization. To address these limitations and improve the robustness of CBMs, we propose the Concept-based Unsupervised Domain Adaptation (CUDA) framework. CUDA is designed to: (1) align concept representations across domains using adversarial training, (2) introduce a relaxation threshold to allow minor domain-specific differences in concept distributions, thereby preventing performance drop due to over-constraints of these distributions, (3) infer concepts directly in the target domain without requiring labeled concept data, enabling CBMs to adapt to diverse domains, and (4) integrate concept learning into conventional domain adaptation (DA) with theoretical guarantees, improving interpretability and establishing new benchmarks for DA. Experiments demonstrate that our approach significantly outperforms the state-of-the-art CBM and DA methods on real-world datasets.

Minghuang Ma, Hadi Pouransari, Daniel Chao et al.

The interest and demand for training deep neural networks have been experiencing rapid growth, spanning a wide range of applications in both academia and industry. However, training them distributed and at scale remains difficult due to the complex ecosystem of tools and hardware involved. One consequence is that the responsibility of orchestrating these complex components is often left to one-off scripts and glue code customized for specific problems. To address these restrictions, we introduce \emph{Alchemist} - an internal service built at Apple from the ground up for \emph{easy}, \emph{fast}, and \emph{scalable} distributed training. We discuss its design, implementation, and examples of running different flavors of distributed training. We also present case studies of its internal adoption in the development of autonomous systems, where training times have been reduced by 10x to keep up with the ever-growing data collection.