Dalin Zhu

Rongzhao He, Weihao Zheng, Leilei Zhao et al.

Attention-based methods have demonstrated exceptional performance in modelling long-range dependencies on spherical cortical surfaces, surpassing traditional Geometric Deep Learning (GDL) models. However, their extensive inference time and high memory demands pose challenges for application to large datasets with limited computing resources. Inspired by the state space model in computer vision, we introduce the attention-free Vision Mamba (Vim) to spherical surfaces, presenting a domain-agnostic architecture for analyzing data on spherical manifolds. Our method achieves surface patching by representing spherical data as a sequence of triangular patches derived from a subdivided icosphere. The proposed Surface Vision Mamba (SiM) is evaluated on multiple neurodevelopmental phenotype regression tasks using cortical surface metrics from neonatal brains. Experimental results demonstrate that SiM outperforms both attention- and GDL-based methods, delivering 4.8 times faster inference and achieving 91.7% lower memory consumption compared to the Surface Vision Transformer (SiT) under the Ico-4 grid partitioning. Sensitivity analysis further underscores the potential of SiM to identify subtle cognitive developmental patterns. The code is available at https://github.com/Rongzhao-He/surface-vision-mamba.

Lingjing Chen, Chengxiu Zhang, Yinqiao Yi et al.

We propose a deep learning-based approach that integrates MRI sequence parameters to improve the accuracy and generalizability of quantitative image synthesis from clinical weighted MRI. Our physics-driven neural network embeds MRI sequence parameters -- repetition time (TR), echo time (TE), and inversion time (TI) -- directly into the model via parameter embedding, enabling the network to learn the underlying physical principles of MRI signal formation. The model takes conventional T1-weighted, T2-weighted, and T2-FLAIR images as input and synthesizes T1, T2, and proton density (PD) quantitative maps. Trained on healthy brain MR images, it was evaluated on both internal and external test datasets. The proposed method achieved high performance with PSNR values exceeding 34 dB and SSIM values above 0.92 for all synthesized parameter maps. It outperformed conventional deep learning models in accuracy and robustness, including data with previously unseen brain structures and lesions. Notably, our model accurately synthesized quantitative maps for these unseen pathological regions, highlighting its superior generalization capability. Incorporating MRI sequence parameters via parameter embedding allows the neural network to better learn the physical characteristics of MR signals, significantly enhancing the performance and reliability of quantitative MRI synthesis. This method shows great potential for accelerating qMRI and improving its clinical utility.