Melek Önen

Riccardo Taiello, Sergen Cansiz, Marc Vesin et al.

Deploying federated learning (FL) in real-world scenarios, particularly in healthcare, poses challenges in communication and security. In particular, with respect to the federated aggregation procedure, researchers have been focusing on the study of secure aggregation (SA) schemes to provide privacy guarantees over the model's parameters transmitted by the clients. Nevertheless, the practical availability of SA in currently available FL frameworks is currently limited, due to computational and communication bottlenecks. To fill this gap, this study explores the implementation of SA within the open-source Fed-BioMed framework. We implement and compare two SA protocols, Joye-Libert (JL) and Low Overhead Masking (LOM), by providing extensive benchmarks in a panel of healthcare data analysis problems. Our theoretical and experimental evaluations on four datasets demonstrate that SA protocols effectively protect privacy while maintaining task accuracy. Computational overhead during training is less than 1% on a CPU and less than 50% on a GPU for large models, with protection phases taking less than 10 seconds. Incorporating SA into Fed-BioMed impacts task accuracy by no more than 2% compared to non-SA scenarios. Overall this study demonstrates the feasibility of SA in real-world healthcare applications and contributes in reducing the gap towards the adoption of privacy-preserving technologies in sensitive applications.

Francesco Cremonesi, Marc Vesin, Sergen Cansiz et al.

The real-world implementation of federated learning is complex and requires research and development actions at the crossroad between different domains ranging from data science, to software programming, networking, and security. While today several FL libraries are proposed to data scientists and users, most of these frameworks are not designed to find seamless application in medical use-cases, due to the specific challenges and requirements of working with medical data and hospital infrastructures. Moreover, governance, design principles, and security assumptions of these frameworks are generally not clearly illustrated, thus preventing the adoption in sensitive applications. Motivated by the current technological landscape of FL in healthcare, in this document we present Fed-BioMed: a research and development initiative aiming at translating federated learning (FL) into real-world medical research applications. We describe our design space, targeted users, domain constraints, and how these factors affect our current and future software architecture.

Oualid Zari, Javier Parra-Arnau, Ayşe Ünsal et al.

In this paper, we present a stealthy and effective attack that exposes privacy vulnerabilities in Graph Neural Networks (GNNs) by inferring private links within graph-structured data. Focusing on the inductive setting where new nodes join the graph and an API is used to query predictions, we investigate the potential leakage of private edge information. We also propose methods to preserve privacy while maintaining model utility. Our attack demonstrates superior performance in inferring the links compared to the state of the art. Furthermore, we examine the application of differential privacy (DP) mechanisms to mitigate the impact of our proposed attack, we analyze the trade-off between privacy preservation and model utility. Our work highlights the privacy vulnerabilities inherent in GNNs, underscoring the importance of developing robust privacy-preserving mechanisms for their application.

Riccardo Taiello, Melek Önen, Francesco Capano et al.

Image registration is a key task in medical imaging applications, allowing to represent medical images in a common spatial reference frame. Current approaches to image registration are generally based on the assumption that the content of the images is usually accessible in clear form, from which the spatial transformation is subsequently estimated. This common assumption may not be met in practical applications, since the sensitive nature of medical images may ultimately require their analysis under privacy constraints, preventing to openly share the image content.In this work, we formulate the problem of image registration under a privacy preserving regime, where images are assumed to be confidential and cannot be disclosed in clear. We derive our privacy preserving image registration framework by extending classical registration paradigms to account for advanced cryptographic tools, such as secure multi-party computation and homomorphic encryption, that enable the execution of operations without leaking the underlying data. To overcome the problem of performance and scalability of cryptographic tools in high dimensions, we propose several techniques to optimize the image registration operations by using gradient approximations, and by revisiting the use of homomorphic encryption trough packing, to allow the efficient encryption and multiplication of large matrices. We demonstrate our privacy preserving framework in linear and non-linear registration problems, evaluating its accuracy and scalability with respect to standard, non-private counterparts. Our results show that privacy preserving image registration is feasible and can be adopted in sensitive medical imaging applications.

Zsolt Tujner, Thomas Rooijakkers, Maran van Heesch et al.

In this work, we propose a study on the use of post-quantum cryptographic primitives for the Tor network in order to make it safe in a quantum world. With this aim, the underlying keying material has first been analysed. We observe that breaking the security of the algorithms/protocols that use long- and medium-term keys (usually RSA keys) have the highest impact in security. Therefore, we investigate the cost of quantum-safe variants. These include key generation, key encapsulation and decapsulation. Six different post-quantum cryptographic algorithms that ensure level 1 NIST security are evaluated. We further target the Tor circuit creation operation and evaluate the overhead of the post-quantum variant. This comparative study is performed through a reference implementation based on SweetOnions that simulates Tor with slight simplifications. We show that a quantum-safe Tor circuit creation is possible and suggest two versions - one that can be used in a purely quantum-safe setting, and one that can be used in a hybrid setting.