Aarav Mehta

Andrea Dunn Beltran, Daniel Rho, Aarav Mehta et al.

Bronchoscopic navigation relies on registering endoscopic video to a preoperative CT scan, but respiratory motion deforms the airway by 5-20 mm, creating CT-to-body divergence that limits localization accuracy. In practice, this is mitigated through breath-hold protocols, which attempt to match the intraoperative anatomy to a static CT, but are difficult to reproduce and disrupt clinical workflow. We propose to eliminate the need for breath-hold protocols by leveraging patient-specific respiratory modeling. Paired inhale-exhale CT scans, already acquired for planning, implicitly define the patient-specific deformation space of the breathing airway. By registering these scans, we reduce respiratory motion to a single scalar breathing phase per frame, constraining all reconstructions to anatomically observed configurations. We embed this representation within a mesh-anchored Gaussian splatting framework, where a lightweight estimator infers breathing phase directly from endoscopic RGB, enabling continuous, deformation-aware reconstruction throughout the respiratory cycle without breath-holds or external sensing. To enable quantitative evaluation, we introduce RESPIRE, a physically grounded bronchoscopy simulation pipeline with per-frame ground truth for geometry, pose, breathing phase, and deformation. Experiments on RESPIRE show that our approach achieves geometrically faithful reconstruction, over 20x faster training, and 1.22 mm target localization accuracy (within the 3mm clinically relevant tolerances) outperforming unconstrained single-CT baselines. Please check out our website for additional visuals: https://asdunnbe.github.io/RESPIRE/

Aarav Mehta, Priya Deshmukh, Vikram Singh et al.

Accurate localization of organ boundaries is critical in medical imaging for segmentation, registration, surgical planning, and radiotherapy. While deep convolutional networks (ConvNets) have advanced general-purpose edge detection to near-human performance on natural images, their outputs often lack precise localization, a limitation that is particularly harmful in medical applications where millimeter-level accuracy is required. Building on a systematic analysis of ConvNet edge outputs, we propose a medically focused crisp edge detector that adapts a novel top-down backward refinement architecture to medical images (2D and volumetric). Our method progressively upsamples and fuses high-level semantic features with fine-grained low-level cues through a backward refinement pathway, producing high-resolution, well-localized organ boundaries. We further extend the design to handle anisotropic volumes by combining 2D slice-wise refinement with light 3D context aggregation to retain computational efficiency. Evaluations on several CT and MRI organ datasets demonstrate substantially improved boundary localization under strict criteria (boundary F-measure, Hausdorff distance) compared to baseline ConvNet detectors and contemporary medical edge/contour methods. Importantly, integrating our crisp edge maps into downstream pipelines yields consistent gains in organ segmentation (higher Dice scores, lower boundary errors), more accurate image registration, and improved delineation of lesions near organ interfaces. The proposed approach produces clinically valuable, crisp organ edges that materially enhance common medical-imaging tasks.