Keshava Katti

Ramya Muthukrishnan, Angelina Heyler, Keshava Katti et al.

In this study, we automate quantitative mammographic breast density estimation with neural networks and show that this tool is a strong use case for federated learning on multi-institutional datasets. Our dataset included bilateral CC-view and MLO-view mammographic images from two separate institutions. Two U-Nets were separately trained on algorithm-generated labels to perform segmentation of the breast and dense tissue from these images and subsequently calculate breast percent density (PD). The networks were trained with federated learning and compared to three non-federated baselines, one trained on each single-institution dataset and one trained on the aggregated multi-institution dataset. We demonstrate that training on multi-institution datasets is critical to algorithm generalizability. We further show that federated learning on multi-institutional datasets improves model generalization to unseen data at nearly the same level as centralized training on multi-institutional datasets, indicating that federated learning can be applied to our method to improve algorithm generalizability while maintaining patient privacy.

Keshava Katti, Pratik Chaudhari, Deep Jariwala

Classical computing is beginning to encounter fundamental limits of energy efficiency. This presents a challenge that can no longer be solved by strategies such as increasing circuit density or refining standard semiconductor processes. The growing computational and memory demands of artificial intelligence (AI) require disruptive innovation in how information is represented, stored, communicated, and processed. By leveraging novel device modalities and compute-in-memory (CIM), in addition to analog dynamics and sparse communication inspired by the brain, neuromorphic computing offers a promising path toward improvements in the energy efficiency and scalability of current AI systems. But realizing this potential is not a matter of replacing one chip with another; rather, it requires a co-design effort, spanning new materials and non-volatile device structures, novel mixed-signal circuits and architectures, and learning algorithms tailored to the physics of these substrates. This article surveys the key limitations of classical complementary metal-oxide-semiconductor (CMOS) technology and outlines how such cross-layer neuromorphic approaches may overcome them.