Mette Olufsen

Jay Aodh Mackenzie, Megan Jeanne Miller, Nicholas Hill et al.

Numerical simulations of real-world phenomena require a computational scheme and a computational domain. In the context of haemodynamics, the computational domain is the blood vessel network through which blood flows. Such networks contain millions of vessels that are joined in series and in parallel. It is computationally unfeasible to explicitly simulate blood flow throughout the network. From a single porcine left coronary arterial tree, we develop a data pipeline to obtain computational domains for haemodynamic simulations in the myocardium from a graph representing a partial coronary arterial tree. In addition, we develop a method to ascertain which subregions of the left-ventricular wall are more likely to be perfused via a given artery, using a comparison with the American Heart Association division of the left ventricle for validation.

Bonny Banerjee, Masoumeh Heidari Kapourchali, Murchana Baruah et al.

Round-the-clock monitoring of human behavior and emotions is required in many healthcare applications which is very expensive but can be automated using machine learning (ML) and sensor technologies. Unfortunately, the lack of infrastructure for collection and sharing of such data is a bottleneck for ML research applied to healthcare. Our goal is to circumvent this bottleneck by simulating a human body in virtual environment. This will allow generation of potentially infinite amounts of shareable data from an individual as a function of his actions, interactions and emotions in a care facility or at home, with no risk of confidentiality breach or privacy invasion. In this paper, we develop for the first time a system consisting of computational models for synchronously synthesizing skeletal motion, electrocardiogram, blood pressure, respiration, and skin conductance signals as a function of an open-ended set of actions and emotions. Our experimental evaluations, involving user studies, benchmark datasets and comparison to findings in the literature, show that our models can generate skeletal motion and physiological signals with high fidelity. The proposed framework is modular and allows the flexibility to experiment with different models. In addition to facilitating ML research for round-the-clock monitoring at a reduced cost, the proposed framework will allow reusability of code and data, and may be used as a training tool for ML practitioners and healthcare professionals.