Paul Yi

Beepul Bharti, Paul Yi, Jeremias Sulam

As the use of machine learning models in real world high-stakes decision settings continues to grow, it is highly important that we are able to audit and control for any potential fairness violations these models may exhibit towards certain groups. To do so, one naturally requires access to sensitive attributes, such as demographics, gender, or other potentially sensitive features that determine group membership. Unfortunately, in many settings, this information is often unavailable. In this work we study the well known \emph{equalized odds} (EOD) definition of fairness. In a setting without sensitive attributes, we first provide tight and computable upper bounds for the EOD violation of a predictor. These bounds precisely reflect the worst possible EOD violation. Second, we demonstrate how one can provably control the worst-case EOD by a new post-processing correction method. Our results characterize when directly controlling for EOD with respect to the predicted sensitive attributes is -- and when is not -- optimal when it comes to controlling worst-case EOD. Our results hold under assumptions that are milder than previous works, and we illustrate these results with experiments on synthetic and real datasets.

Beepul Bharti, Paul Yi, Jeremias Sulam

As complex machine learning models continue to find applications in high-stakes decision-making scenarios, it is crucial that we can explain and understand their predictions. Post-hoc explanation methods provide useful insights by identifying important features in an input $\mathbf{x}$ with respect to the model output $f(\mathbf{x})$. In this work, we formalize and study two precise notions of feature importance for general machine learning models: sufficiency and necessity. We demonstrate how these two types of explanations, albeit intuitive and simple, can fall short in providing a complete picture of which features a model finds important. To this end, we propose a unified notion of importance that circumvents these limitations by exploring a continuum along a necessity-sufficiency axis. Our unified notion, we show, has strong ties to other popular definitions of feature importance, like those based on conditional independence and game-theoretic quantities like Shapley values. Crucially, we demonstrate how a unified perspective allows us to detect important features that could be missed by either of the previous approaches alone.

Jillur Rahman Saurav, Thuong Le Hoai Pham, Pritam Mukherjee et al.

Virtual immunohistochemistry (IHC) staining from hematoxylin and eosin (H&E) images can accelerate diagnostics by providing preliminary molecular insight directly from routine sections, reducing the need for repeat sectioning when tissue is limited. Existing methods improve realism through contrastive objectives, prototype matching, or domain alignment, yet the generator itself receives no direct guidance from pathology foundation models. We present UNIStainNet, a SPADE-UNet conditioned on dense spatial tokens from a frozen pathology foundation model (UNI), providing tissue-level semantic guidance for stain translation. A misalignment-aware loss suite preserves stain quantification accuracy, and learned stain embeddings enable a single model to serve multiple IHC markers simultaneously. On MIST, UNIStainNet achieves state-of-the-art distributional metrics on all four stains (HER2, Ki67, ER, PR) from a single unified model, where prior methods typically train separate per-stain models. On BCI, it also achieves the best distributional metrics. A tissue-type stratified failure analysis reveals that remaining errors are systematic, concentrating in non-tumor tissue. Code is available at https://github.com/facevoid/UNIStainNet.