Guibo Luo

Xiuling Wang, Xin Huang, Guibo Luo et al.

Graph generative diffusion models have recently emerged as a powerful paradigm for generating complex graph structures, effectively capturing intricate dependencies and relationships within graph data. However, the privacy risks associated with these models remain largely unexplored. In this paper, we investigate information leakage in such models through three types of black-box inference attacks. First, we design a graph reconstruction attack, which can reconstruct graphs structurally similar to those training graphs from the generated graphs. Second, we propose a property inference attack to infer the properties of the training graphs, such as the average graph density and the distribution of densities, from the generated graphs. Third, we develop two membership inference attacks to determine whether a given graph is present in the training set. Extensive experiments on three different types of graph generative diffusion models and six real-world graphs demonstrate the effectiveness of these attacks, significantly outperforming the baseline approaches. Finally, we propose two defense mechanisms that mitigate these inference attacks and achieve a better trade-off between defense strength and target model utility than existing methods. Our code is available at https://zenodo.org/records/17946102.

Wang Bin, Ao Yang, Kedan Li et al.

In the domain of software security testing, Directed Grey-Box Fuzzing (DGF) has garnered widespread attention for its efficient target localization and excellent detection performance. However, existing approaches measure only the physical distance between seed execution paths and target locations, overlooking logical relationships among code segments. This omission can yield redundant or misleading guidance in complex binaries, weakening DGF's real-world effectiveness. To address this, we introduce \textbf{attention distance}, a novel metric that leverages a large language model's contextual analysis to compute attention scores between code elements and reveal their intrinsic connections. Under the same AFLGo configuration -- without altering any fuzzing components other than the distance metric -- replacing physical distances with attention distances across 38 real vulnerability reproduction experiments delivers a \textbf{3.43$\times$} average increase in testing efficiency over the traditional method. Compared to state-of-the-art directed fuzzers DAFL and WindRanger, our approach achieves \textbf{2.89$\times$} and \textbf{7.13$\times$} improvements, respectively. To further validate the generalizability of attention distance, we integrate it into DAFL and WindRanger, where it also consistently enhances their original performance. All related code and datasets are publicly available at https://github.com/TheBinKing/Attention\_Distance.git.

Yiyu Gui, MingZhi Chen, Yuqi Su et al.

In recent years, with the development of deep learning, electroencephalogram (EEG) classification networks have achieved certain progress. Transformer-based models can perform well in capturing long-term dependencies in EEG signals. However, their quadratic computational complexity poses a substantial computational challenge. Moreover, most EEG classification models are only suitable for single tasks and struggle with generalization across different tasks, particularly when faced with variations in signal length and channel count. In this paper, we introduce EEGMamba, the first universal EEG classification network to truly implement multi-task learning for EEG applications. EEGMamba seamlessly integrates the Spatio-Temporal-Adaptive (ST-Adaptive) module, bidirectional Mamba, and Mixture of Experts (MoE) into a unified framework. The proposed ST-Adaptive module performs unified feature extraction on EEG signals of different lengths and channel counts through spatial-adaptive convolution and incorporates a class token to achieve temporal-adaptability. Moreover, we design a bidirectional Mamba particularly suitable for EEG signals for further feature extraction, balancing high accuracy, fast inference speed, and efficient memory-usage in processing long EEG signals. To enhance the processing of EEG data across multiple tasks, we introduce task-aware MoE with a universal expert, effectively capturing both differences and commonalities among EEG data from different tasks. We evaluate our model on eight publicly available EEG datasets, and the experimental results demonstrate its superior performance in four types of tasks: seizure detection, emotion recognition, sleep stage classification, and motor imagery. The code is set to be released soon.

Mingzhi Chen, Yiyu Gui, Yuqi Su et al.

Electroencephalogram (EEG) classification has been widely used in various medical and engineering applications, where it is important for understanding brain function, diagnosing diseases, and assessing mental health conditions. However, the scarcity of EEG data severely restricts the performance of EEG classification networks, and generative model-based data augmentation methods have emerged as potential solutions to overcome this challenge. There are two problems with existing methods: (1) The quality of the generated EEG signals is not high; (2) The enhancement of EEG classification networks is not effective. In this paper, we propose a Transformer-based denoising diffusion probabilistic model and a generated data-based augmentation method to address the above two problems. For the characteristics of EEG signals, we propose a constant-factor scaling method to preprocess the signals, which reduces the loss of information. We incorporated Multi-Scale Convolution and Dynamic Fourier Spectrum Information modules into the model, improving the stability of the training process and the quality of the generated data. The proposed augmentation method randomly reassemble the generated data with original data in the time-domain to obtain vicinal data, which improves the model performance by minimizing the empirical risk and the vicinal risk. We verify the proposed augmentation method on four EEG datasets for four tasks and observe significant accuracy performance improvements: 14.00% on the Bonn dataset; 6.38% on the SleepEDF-20 dataset; 9.42% on the FACED dataset; 2.5% on the Shu dataset. We will make the code of our method publicly accessible soon.

Jianhao Xie, Ruofan Liao, Ziang Zhang et al.

Detecting polyps through colonoscopy is an important task in medical image segmentation, which provides significant assistance and reference value for clinical surgery. However, accurate segmentation of polyps is a challenging task due to two main reasons. Firstly, polyps exhibit various shapes and colors. Secondly, the boundaries between polyps and their normal surroundings are often unclear. Additionally, significant differences between different datasets lead to limited generalization capabilities of existing methods. To address these issues, we propose a segmentation model based on Prompt-Mamba, which incorporates the latest Vision-Mamba and prompt technologies. Compared to previous models trained on the same dataset, our model not only maintains high segmentation accuracy on the validation part of the same dataset but also demonstrates superior accuracy on unseen datasets, exhibiting excellent generalization capabilities. Notably, we are the first to apply the Vision-Mamba architecture to polyp segmentation and the first to utilize prompt technology in a polyp segmentation model. Our model efficiently accomplishes segmentation tasks, surpassing previous state-of-the-art methods by an average of 5% across six datasets. Furthermore, we have developed multiple versions of our model with scaled parameter counts, achieving better performance than previous models even with fewer parameters. Our code and trained weights will be released soon.

Yuxi Liu, Guibo Luo, Yuesheng Zhu

Medical image segmentation is crucial for clinical diagnosis. The Segmentation Anything Model (SAM) serves as a powerful foundation model for visual segmentation and can be adapted for medical image segmentation. However, medical imaging data typically contain privacy-sensitive information, making it challenging to train foundation models with centralized storage and sharing. To date, there are few foundation models tailored for medical image deployment within the federated learning framework, and the segmentation performance, as well as the efficiency of communication and training, remain unexplored. In response to these issues, we developed Federated Foundation models for Medical image Segmentation (FedFMS), which includes the Federated SAM (FedSAM) and a communication and training-efficient Federated SAM with Medical SAM Adapter (FedMSA). Comprehensive experiments on diverse datasets are conducted to investigate the performance disparities between centralized training and federated learning across various configurations of FedFMS. The experiments revealed that FedFMS could achieve performance comparable to models trained via centralized training methods while maintaining privacy. Furthermore, FedMSA demonstrated the potential to enhance communication and training efficiency. Our model implementation codes are available at https://github.com/LIU-YUXI/FedFMS.

Hanwen Zhang, Qiaojin Shen, Yuxi Liu et al.

Foundation Models (FMs) have demonstrated strong generalization across diverse vision tasks. However, their deployment in federated settings is hindered by high computational demands, substantial communication overhead, and significant inference costs. We propose DSFedMed, a dual-scale federated framework that enables mutual knowledge distillation between a centralized foundation model and lightweight client models for medical image segmentation. To support knowledge distillation, a set of high-quality medical images is generated to replace real public datasets, and a learnability-guided sample selection strategy is proposed to enhance efficiency and effectiveness in dual-scale distillation. This mutual distillation enables the foundation model to transfer general knowledge to lightweight clients, while also incorporating client-specific insights to refine the foundation model. Evaluations on five medical imaging segmentation datasets show that DSFedMed achieves an average 2 percent improvement in Dice score while reducing communication costs and inference time by nearly 90 percent compared to existing federated foundation model baselines. These results demonstrate significant efficiency gains and scalability for resource-limited federated deployments.

Shudong Liu, Hanwen Zhang, Xiuling Wang et al.

One-shot federated learning (OSFL) reduces the communication cost and privacy risks of iterative federated learning by constructing a global model with a single round of communication. However, most existing methods struggle to achieve robust performance on real-world domains such as medical imaging, or are inefficient when handling non-IID (Independent and Identically Distributed) data. To address these limitations, we introduce FALCON, a framework that enhances the effectiveness of OSFL over non-IID image data. The core idea of FALCON is to leverage the feature-aware hierarchical token sequences generation and knowledge distillation into OSFL. First, each client leverages a pretrained visual encoder with hierarchical scale encoding to compress images into hierarchical token sequences, which capture multi-scale semantics. Second, a multi-scale autoregressive transformer generator is used to model the distribution of these token sequences and generate the synthetic sequences. Third, clients upload the synthetic sequences along with the local classifier trained on the real token sequences to the server. Finally, the server incorporates knowledge distillation into global training to reduce reliance on precise distribution modeling. Experiments on medical and natural image datasets validate the effectiveness of FALCON in diverse non-IID scenarios, outperforming the best OSFL baselines by 9.58% in average accuracy.

Zhekai Zhou, Guibo Luo, Mingzhi Chen et al.

The federated learning paradigm is wellsuited for the field of medical image analysis, as it can effectively cope with machine learning on isolated multicenter data while protecting the privacy of participating parties. However, current research on optimization algorithms in federated learning often focuses on limited datasets and scenarios, primarily centered around natural images, with insufficient comparative experiments in medical contexts. In this work, we conduct a comprehensive evaluation of several state-of-the-art federated learning algorithms in the context of medical imaging. We conduct a fair comparison of classification models trained using various federated learning algorithms across multiple medical imaging datasets. Additionally, we evaluate system performance metrics, such as communication cost and computational efficiency, while considering different federated learning architectures. Our findings show that medical imaging datasets pose substantial challenges for current federated learning optimization algorithms. No single algorithm consistently delivers optimal performance across all medical federated learning scenarios, and many optimization algorithms may underperform when applied to these datasets. Our experiments provide a benchmark and guidance for future research and application of federated learning in medical imaging contexts. Furthermore, we propose an efficient and robust method that combines generative techniques using denoising diffusion probabilistic models with label smoothing to augment datasets, widely enhancing the performance of federated learning on classification tasks across various medical imaging datasets. Our code will be released on GitHub, offering a reliable and comprehensive benchmark for future federated learning studies in medical imaging.

Jianhao Xie, Ziang Zhang, Zhenyu Weng et al.

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in medical imaging remains constrained due to their reliance on large-scale medical datasets and the need for higher image quality. To address these challenges, we present MedDiff-FT, a controllable medical image generation method that fine-tunes a diffusion foundation model to produce medical images with structural dependency and domain specificity in a data-efficient manner. During inference, a dynamic adaptive guiding mask enforces spatial constraints to ensure anatomically coherent synthesis, while a lightweight stochastic mask generator enhances diversity through hierarchical randomness injection. Additionally, an automated quality assessment protocol filters suboptimal outputs using feature-space metrics, followed by mask corrosion to refine fidelity. Evaluated on five medical segmentation datasets,MedDiff-FT's synthetic image-mask pairs improve SOTA method's segmentation performance by an average of 1% in Dice score. The framework effectively balances generation quality, diversity, and computational efficiency, offering a practical solution for medical data augmentation. The code is available at https://github.com/JianhaoXie1/MedDiff-FT.

Hongbo Jin, Ruyang Liu, Wenhao Zhang et al.

System2 reasoning is developing rapidly these days with the emergence of Deep- Thinking Models and chain-of-thought technology, which has become a centralized discussion point in the AI community. However, there is a relative gap in the research on complex video reasoning at present. In this work, we propose CoT-Vid, a novel training-free paradigm for the video domain with a multistage complex reasoning design. Distinguishing from existing video LLMs, which rely heavily on perceptual abilities, it achieved surprising performance gain with explicit reasoning mechanism. The paradigm consists of three main components: dynamic inference path routing, problem decoupling strategy, and video self-consistency verification. In addition, we propose a new standard for categorization of video questions. CoT- Vid showed outstanding results on a wide range of benchmarks, and outperforms its base model by 9.3% on Egochema and 5.6% on VideoEspresso, rivalling or even surpassing larger and proprietary models, such as GPT-4V, GPT-4o and Gemini-1.5-flash. Our codebase will be publicly available soon.

Yanhao Li, Lu Ma, Jiaran Zhang et al.

Existing approaches typically rely on fixed length penalties, but such penalties are hard to tune and fail to adapt to the evolving reasoning abilities of LLMs, leading to suboptimal trade-offs between accuracy and conciseness. To address this challenge, we propose Leash (adaptive LEngth penAlty and reward SHaping), a reinforcement learning framework for efficient reasoning in LLMs. We formulate length control as a constrained optimization problem and employ a Lagrangian primal-dual method to dynamically adjust the penalty coefficient. When generations exceed the target length, the penalty is intensified; when they are shorter, it is relaxed. This adaptive mechanism guides models toward producing concise reasoning without sacrificing task performance. Experiments on Deepseek-R1-Distill-Qwen-1.5B and Qwen3-4B-Thinking-2507 show that Leash reduces the average reasoning length by 60% across diverse tasks - including in-distribution mathematical reasoning and out-of-distribution domains such as coding and instruction following - while maintaining competitive performance. Our work thus presents a practical and effective paradigm for developing controllable and efficient LLMs that balance reasoning capabilities with computational budgets.

Yufei Ma, Hanwen Zhang, Qiya Yang et al.

In multi-center scenarios, One-Shot Federated Learning (OSFL) has attracted increasing attention due to its low communication overhead, requiring only a single round of transmission. However, existing generative model-based OSFL methods suffer from low training efficiency and potential privacy leakage in the healthcare domain. Additionally, achieving convergence within a single round of model aggregation is challenging under non-Independent and Identically Distributed (non-IID) data. To address these challenges, in this paper a modified OSFL framework is proposed, in which a new Feature-Guided Rectified Flow Model (FG-RF) and Dual-Layer Knowledge Distillation (DLKD) aggregation method are developed. FG-RF on the client side accelerates generative modeling in medical imaging scenarios while preserving privacy by synthesizing feature-level images rather than pixel-level images. To handle non-IID distributions, DLKD enables the global student model to simultaneously mimic the output logits and align the intermediate-layer features of client-side teacher models during aggregation. Experimental results on three non-IID medical imaging datasets show that our new framework and method outperform multi-round federated learning approaches, achieving up to 21.73% improvement, and exceeds the baseline FedISCA by an average of 21.75%. Furthermore, our experiments demonstrate that feature-level synthetic images significantly reduce privacy leakage risks compared to pixel-level synthetic images. The code is available at https://github.com/LMIAPC/one-shot-fl-medical.

Renyu Fu, Guibo Luo

Chain-of-Thought (CoT) has become a cornerstone of reasoning in large language models, yet its effectiveness is constrained by the limited expressiveness of discrete token sampling. Recent latent reasoning approaches attempt to alleviate this limitation by replacing discrete tokens with soft embeddings (probability-weighted mixtures of token embeddings) or hidden states, but they commonly suffer from two issues: (1) global activation injects perturbations into high-confidence steps, impairing reasoning stability; and (2) soft embeddings quickly collapse toward the highest-probability token, limiting exploration of alternative trajectories. To address these challenges, we propose SeLaR (Selective Latent Reasoning), a lightweight and training-free framework. SeLaR introduces an entropy-gated mechanism that activates soft embeddings only at low-confidence steps, while preserving discrete decoding at high-confidence steps. Additionally, we propose an entropy-aware contrastive regularization that pushes soft embeddings away from the dominant (highest-probability) token's direction, encouraging sustained exploration of multiple latent reasoning paths. Experiments on five reasoning benchmarks demonstrate that SeLaR consistently outperforms standard CoT and state-of-the-art training-free methods.

Zhekai Zhou, Shudong Liu, Zhaokun Zhou et al.

Federated learning (FL) is a decentralized machine learning paradigm in which multiple clients collaboratively train a shared model without sharing their local private data. However, real-world applications of FL frequently encounter challenges arising from the non-identically and independently distributed (non-IID) local datasets across participating clients, which is particularly pronounced in the field of medical imaging, where shifts in image feature distributions significantly hinder the global model's convergence and performance. To address this challenge, we propose FedMP, a novel method designed to enhance FL under non-IID scenarios. FedMP employs stochastic feature manifold completion to enrich the training space of individual client classifiers, and leverages class-prototypes to guide the alignment of feature manifolds across clients within semantically consistent subspaces, facilitating the construction of more distinct decision boundaries. We validate the effectiveness of FedMP on multiple medical imaging datasets, including those with real-world multi-center distributions, as well as on a multi-domain natural image dataset. The experimental results demonstrate that FedMP outperforms existing FL algorithms. Additionally, we analyze the impact of manifold dimensionality, communication efficiency, and privacy implications of feature exposure in our method.

Biao Guo, Cong Zhou, Fangmin Guo et al.

Most of the current top-down multi-person pose estimation lightweight methods are based on multi-branch parallel pure CNN network architecture, which often struggle to capture the global context required for detecting semantically complex keypoints and are hindered by high latency due to their intricate and redundant structures. In this article, an approximate single-branch lightweight global modeling network (LGM-Pose) is proposed to address these challenges. In the network, a lightweight MobileViM Block is designed with a proposed Lightweight Attentional Representation Module (LARM), which integrates information within and between patches using the Non-Parametric Transformation Operation(NPT-Op) to extract global information. Additionally, a novel Shuffle-Integrated Fusion Module (SFusion) is introduced to effectively integrate multi-scale information, mitigating performance degradation often observed in single-branch structures. Experimental evaluations on the COCO and MPII datasets demonstrate that our approach not only reduces the number of parameters compared to existing mainstream lightweight methods but also achieves superior performance and faster processing speeds.

Jianhao Xie, Ziang Zhang, Guibo Luo et al.

Large pre-trained models with their numerous model parameters and extensive training datasets have shown excellent performance in various tasks. Many publicly available medical image datasets do not have a sufficient amount of data so there are few large-scale models in medical imaging. We propose a large-scale Tumor Segmentation Foundation Model (TSFM) with 1.6 billion parameters using Resblock-backbone and Transformer-bottleneck,which has good transfer ability for downstream tasks. To make TSFM exhibit good performance in tumor segmentation, we make full use of the strong spatial correlation between tumors and organs in the medical image, innovatively fuse 7 tumor datasets and 3 multi-organ datasets to build a 3D medical dataset pool, including 2779 cases with totally 300k medical images, whose size currently exceeds many other single publicly available datasets. TSFM is the pre-trained model for medical image segmentation, which also can be transferred to multiple downstream tasks for fine-tuning learning. The average performance of our pre-trained model is 2% higher than that of nnU-Net across various tumor types. In the transfer learning task, TSFM only needs 5% training epochs of nnU-Net to achieve similar performance and can surpass nnU-Net by 2% on average with 10% training epoch. Pre-trained TSFM and its code will be released soon.