Xiaotong Li

Xiaotong Li, Yixiao Ge, Kun Yi et al. · tencent-ai

Image BERT pre-training with masked image modeling (MIM) becomes a popular practice to cope with self-supervised representation learning. A seminal work, BEiT, casts MIM as a classification task with a visual vocabulary, tokenizing the continuous visual signals into discrete vision tokens using a pre-learned dVAE. Despite a feasible solution, the improper discretization hinders further improvements of image pre-training. Since image discretization has no ground-truth answers, we believe that the masked patch should not be assigned with a unique token id even if a better tokenizer can be obtained. In this work, we introduce an improved BERT-style image pre-training method, namely mc-BEiT, which performs MIM proxy tasks towards eased and refined multi-choice training objectives. Specifically, the multi-choice supervision for the masked image patches is formed by the soft probability vectors of the discrete token ids, which are predicted by the off-the-shelf image tokenizer and further refined by high-level inter-patch perceptions resorting to the observation that similar patches should share their choices. Extensive experiments on classification, segmentation, and detection tasks demonstrate the superiority of our method, e.g., the pre-trained ViT-B achieves 84.1% top-1 fine-tuning accuracy on ImageNet-1K classification, 49.2% AP^b and 44.0% AP^m of object detection and instance segmentation on COCO, 50.8% mIOU on ADE20K semantic segmentation, outperforming the competitive counterparts. The code will be available at https://github.com/lixiaotong97/mc-BEiT.

Xiaotong Li, Zixuan Hu, Jun Liu et al. · tencent-ai

Though deep neural networks have achieved impressive success on various vision tasks, obvious performance degradation still exists when models are tested in out-of-distribution scenarios. In addressing this limitation, we ponder that the feature statistics (mean and standard deviation), which carry the domain characteristics of the training data, can be properly manipulated to improve the generalization ability of deep learning models. Existing methods commonly consider feature statistics as deterministic values measured from the learned features and do not explicitly model the uncertain statistics discrepancy caused by potential domain shifts during testing. In this paper, we improve the network generalization ability by modeling domain shifts with uncertainty (DSU), i.e., characterizing the feature statistics as uncertain distributions during training. Specifically, we hypothesize that the feature statistic, after considering the potential uncertainties, follows a multivariate Gaussian distribution. During inference, we propose an instance-wise adaptation strategy that can adaptively deal with the unforeseeable shift and further enhance the generalization ability of the trained model with negligible additional cost. We also conduct theoretical analysis on the aspects of generalization error bound and the implicit regularization effect, showing the efficacy of our method. Extensive experiments demonstrate that our method consistently improves the network generalization ability on multiple vision tasks, including image classification, semantic segmentation, instance retrieval, and pose estimation. Our methods are simple yet effective and can be readily integrated into networks without additional trainable parameters or loss constraints. Code will be released in https://github.com/lixiaotong97/DSU.

Xiaotong Li, Zixuan Hu, Yixiao Ge et al. · tencent-ai

Transfer learning has become crucial in computer vision tasks due to the vast availability of pre-trained deep learning models. However, selecting the optimal pre-trained model from a diverse pool for a specific downstream task remains a challenge. Existing methods for measuring the transferability of pre-trained models rely on statistical correlations between encoded static features and task labels, but they overlook the impact of underlying representation dynamics during fine-tuning, leading to unreliable results, especially for self-supervised models. In this paper, we present an insightful physics-inspired approach named PED to address these challenges. We reframe the challenge of model selection through the lens of potential energy and directly model the interaction forces that influence fine-tuning dynamics. By capturing the motion of dynamic representations to decline the potential energy within a force-driven physical model, we can acquire an enhanced and more stable observation for estimating transferability. The experimental results on 10 downstream tasks and 12 self-supervised models demonstrate that our approach can seamlessly integrate into existing ranking techniques and enhance their performances, revealing its effectiveness for the model selection task and its potential for understanding the mechanism in transfer learning. Code will be available at https://github.com/lixiaotong97/PED.

Kun Yi, Yixiao Ge, Xiaotong Li et al. · tencent-ai

Since the development of self-supervised visual representation learning from contrastive learning to masked image modeling (MIM), there is no significant difference in essence, that is, how to design proper pretext tasks for vision dictionary look-up. MIM recently dominates this line of research with state-of-the-art performance on vision Transformers (ViTs), where the core is to enhance the patch-level visual context capturing of the network via denoising auto-encoding mechanism. Rather than tailoring image tokenizers with extra training stages as in previous works, we unleash the great potential of contrastive learning on denoising auto-encoding and introduce a pure MIM method, ConMIM, to produce simple intra-image inter-patch contrastive constraints as the sole learning objectives for masked patch prediction. We further strengthen the denoising mechanism with asymmetric designs, including image perturbations and model progress rates, to improve the network pre-training. ConMIM-pretrained models with various scales achieve competitive results on downstream image classification, semantic segmentation, object detection, and instance segmentation tasks, e.g., on ImageNet-1K classification, we achieve 83.9% top-1 accuracy with ViT-Small and 85.3% with ViT-Base without extra data for pre-training.

Haozhe Zhao, Shuzheng Si, Zhenhailong Wang et al.

Scientific figures are among the most effective means of communicating complex research ideas, yet producing publication-quality illustrations remains one of the most labor-intensive parts of paper preparation. Existing automated systems each target a single figure type under text-only input, leaving the diversity of types and conditions researchers actually use unaddressed; their raster outputs further cannot be locally revised. Because scientific figures are structured compositions of discrete semantic components, the localized errors generators produce on such layouts demand not a stronger backbone but a harness. We instantiate this harness in two complementary systems: Crafter, a multi-agent harness for figure generation that generalizes across figure types and input conditions without architectural changes, and CraftEditor, which applies the same pattern to convert raster outputs into editable SVGs. Moreover, we introduce CraftBench, a benchmark spanning three figure types and four input conditions with human quality annotation. Experiments show that Crafter substantially outperforms both standalone generators and the agentic baseline on PaperBanana-Bench and CraftBench, with ablations confirming each component's independent contribution; CraftEditor faithfully converts outputs into editable SVGs that surpass all baselines. Our code and benchmark are available at https://github.com/HaozheZhao/Crafter.

Xiaotong Li, Fan Zhang, Haiwen Diao et al.

Existing Multimodal Large Language Models (MLLMs) increasingly emphasize complex understanding of various visual elements, including multiple objects, text information, and spatial relations. Their development for comprehensive visual perception hinges on the availability of high-quality image-text datasets that offer diverse visual elements and throughout image descriptions. However, the scarcity of such hyper-detailed datasets currently hinders progress within the MLLM community. The bottleneck stems from the limited perceptual capabilities of current caption engines, which fall short in providing complete and accurate annotations. To facilitate the cutting-edge research of MLLMs on comprehensive vision perception, we thereby propose Perceptual Fusion, using a low-budget but highly effective caption engine for complete and accurate image descriptions. Specifically, Perceptual Fusion integrates diverse perception experts as image priors to provide explicit information on visual elements and adopts an efficient MLLM as a centric pivot to mimic advanced MLLMs' perception abilities. We carefully select 1M highly representative images from uncurated LAION dataset and generate dense descriptions using our engine, dubbed DenseFusion-1M. Extensive experiments validate that our engine outperforms its counterparts, where the resulting dataset significantly improves the perception and cognition abilities of existing MLLMs across diverse vision-language benchmarks, especially with high-resolution images as inputs. The dataset and code are publicly available at https://github.com/baaivision/DenseFusion.

Meituan LongCat Team, Bin Xiao, Chao Wang et al.

The prevailing Next-Token Prediction (NTP) paradigm has driven the success of large language models through discrete autoregressive modeling. However, contemporary multimodal systems remain language-centric, often treating non-linguistic modalities as external attachments, leading to fragmented architectures and suboptimal integration. To transcend this limitation, we introduce Discrete Native Autoregressive (DiNA), a unified framework that represents multimodal information within a shared discrete space, enabling a consistent and principled autoregressive modeling across modalities. A key innovation is the Discrete Native Any-resolution Visual Transformer (dNaViT), which performs tokenization and de-tokenization at arbitrary resolutions, transforming continuous visual signals into hierarchical discrete tokens. Building on this foundation, we develop LongCat-Next, a native multimodal model that processes text, vision, and audio under a single autoregressive objective with minimal modality-specific design. As an industrial-strength foundation model, it excels at seeing, painting, and talking within a single framework, achieving strong performance across a wide range of multimodal benchmarks. In particular, LongCat-Next addresses the long-standing performance ceiling of discrete vision modeling on understanding tasks and provides a unified approach to effectively reconcile the conflict between understanding and generation. As an attempt toward native multimodality, we open-source the LongCat-Next and its tokenizers, hoping to foster further research and development in the community. GitHub: https://github.com/meituan-longcat/LongCat-Next

Chenyu Hu, Xiaotong Li, Hao Zhu et al.

Point cloud processing has become a cornerstone technology in many 3D vision tasks. However, arbitrary rotations introduce variations in point cloud orientations, posing a long-standing challenge for effective representation learning. The core of this issue is the disruption of the point cloud's intrinsic directional characteristics caused by rotational perturbations. Recent methods attempt to implicitly model rotational equivariance and invariance, preserving directional information and propagating it into deep semantic spaces. Yet, they often fall short of fully exploiting the multiscale directional nature of point clouds to enhance feature representations. To address this, we propose the Direction-Perceptive Vector Network (DiPVNet). At its core is an atomic dot-product operator that simultaneously encodes directional selectivity and rotation invariance--endowing the network with both rotational symmetry modeling and adaptive directional perception. At the local level, we introduce a Learnable Local Dot-Product (L2DP) Operator, which enables interactions between a center point and its neighbors to adaptively capture the non-uniform local structures of point clouds. At the global level, we leverage generalized harmonic analysis to prove that the dot-product between point clouds and spherical sampling vectors is equivalent to a direction-aware spherical Fourier transform (DASFT). This leads to the construction of a global directional response spectrum for modeling holistic directional structures. We rigorously prove the rotation invariance of both operators. Extensive experiments on challenging scenarios involving noise and large-angle rotations demonstrate that DiPVNet achieves state-of-the-art performance on point cloud classification and segmentation tasks. Our code is available at https://github.com/wxszreal0/DiPVNet.

Zeyuan Wang, Qiang Zhang, Keyan Ding et al.

Large Language Models (LLMs) have revolutionized the field of natural language processing, but they fall short in comprehending biological sequences such as proteins. To address this challenge, we propose InstructProtein, an innovative LLM that possesses bidirectional generation capabilities in both human and protein languages: (i) taking a protein sequence as input to predict its textual function description and (ii) using natural language to prompt protein sequence generation. To achieve this, we first pre-train an LLM on both protein and natural language corpora, enabling it to comprehend individual languages. Then supervised instruction tuning is employed to facilitate the alignment of these two distinct languages. Herein, we introduce a knowledge graph-based instruction generation framework to construct a high-quality instruction dataset, addressing annotation imbalance and instruction deficits in existing protein-text corpus. In particular, the instructions inherit the structural relations between proteins and function annotations in knowledge graphs, which empowers our model to engage in the causal modeling of protein functions, akin to the chain-of-thought processes in natural languages. Extensive experiments on bidirectional protein-text generation tasks show that InstructProtein outperforms state-of-the-art LLMs by large margins. Moreover, InstructProtein serves as a pioneering step towards text-based protein function prediction and sequence design, effectively bridging the gap between protein and human language understanding.

Shuhao Gu, Jialing Zhang, Siyuan Zhou et al.

Recently, Vision-Language Models (VLMs) have achieved remarkable progress in multimodal tasks, and multimodal instruction data serves as the foundation for enhancing VLM capabilities. Despite the availability of several open-source multimodal datasets, limitations in the scale and quality of open-source instruction data hinder the performance of VLMs trained on these datasets, leading to a significant gap compared to models trained on closed-source data. To address this challenge, we introduce Infinity-MM, a large-scale multimodal instruction dataset. We collected the available multimodal instruction datasets and performed unified preprocessing, resulting in a dataset with over 40 million samples that ensures diversity and accuracy. Furthermore, to enable large-scale expansion of instruction data and support the continuous acquisition of high-quality data, we propose a synthetic instruction generation method based on a tagging system and open-source VLMs. By establishing correspondences between different types of images and associated instruction types, this method can provide essential guidance during data synthesis. Leveraging this high-quality data, we have trained a 2-billion-parameter Vision-Language Model, Aquila-VL-2B, which achieves state-of-the-art (SOTA) performance among models of similar scale. The data is available at: https://huggingface.co/datasets/BAAI/Infinity-MM.

Haiwen Diao, Xiaotong Li, Yufeng Cui et al.

Existing encoder-free vision-language models (VLMs) are rapidly narrowing the performance gap with their encoder-based counterparts, highlighting the promising potential for unified multimodal systems with structural simplicity and efficient deployment. We systematically clarify the performance gap between VLMs using pre-trained vision encoders, discrete tokenizers, and minimalist visual layers from scratch, deeply excavating the under-examined characteristics of encoder-free VLMs. We develop efficient strategies for encoder-free VLMs that rival mainstream encoder-based ones. After an in-depth investigation, we launch EVEv2.0, a new and improved family of encoder-free VLMs. We show that: (i) Properly decomposing and hierarchically associating vision and language within a unified model reduces interference between modalities. (ii) A well-designed training strategy enables effective optimization for encoder-free VLMs. Through extensive evaluation, our EVEv2.0 represents a thorough study for developing a decoder-only architecture across modalities, demonstrating superior data efficiency and strong vision-reasoning capability. Code is publicly available at: https://github.com/baaivision/EVE.

Meituan LongCat Team, Bayan, Bei Li et al.

We introduce LongCat-Flash, a 560-billion-parameter Mixture-of-Experts (MoE) language model designed for both computational efficiency and advanced agentic capabilities. Stemming from the need for scalable efficiency, LongCat-Flash adopts two novel designs: (a) Zero-computation Experts, which enables dynamic computational budget allocation and activates 18.6B-31.3B (27B on average) per token depending on contextual demands, optimizing resource usage. (b) Shortcut-connected MoE, which enlarges the computation-communication overlap window, demonstrating notable gains in inference efficiency and throughput compared to models of a comparable scale. We develop a comprehensive scaling framework for large models that combines hyperparameter transfer, model-growth initialization, a multi-pronged stability suite, and deterministic computation to achieve stable and reproducible training. Notably, leveraging the synergy among scalable architectural design and infrastructure efforts, we complete model training on more than 20 trillion tokens within 30 days, while achieving over 100 tokens per second (TPS) for inference at a cost of \$0.70 per million output tokens. To cultivate LongCat-Flash towards agentic intelligence, we conduct a large-scale pre-training on optimized mixtures, followed by targeted mid- and post-training on reasoning, code, and instructions, with further augmentation from synthetic data and tool use tasks. Comprehensive evaluations demonstrate that, as a non-thinking foundation model, LongCat-Flash delivers highly competitive performance among other leading models, with exceptional strengths in agentic tasks. The model checkpoint of LongCat-Flash is open-sourced to foster community research. LongCat Chat: https://longcat.ai Hugging Face: https://huggingface.co/meituan-longcat GitHub: https://github.com/meituan-longcat

Xiaotong Li, Gang Chen, Javier Alonso-Mora

Open-world object manipulation remains a fundamental challenge in robotics. While Vision-Language-Action (VLA) models have demonstrated promising results, they rely heavily on large-scale robot action demonstrations, which are costly to collect and can hinder out-of-distribution generalization. In this paper, we propose an explicit-world-model-based framework for open-world manipulation that achieves zero-shot generalization by constructing a physically grounded digital twin of the environment. The framework integrates open-set perception, digital-twin reconstruction, sampling and evaluation of interaction strategies. By constructing a digital twin of the environment, our approach efficiently explores and evaluates manipulation strategies in physic-enabled simulator and reliably deploys the chosen strategy to the real world. Experimentally, the proposed framework is able to perform multiple open-set manipulation tasks without any task-specific action demonstrations, proving strong zero-shot generalization on both the task and object levels. Project Page: https://bojack-bj.github.io/projects/thesis/

Xiang Zhuang, Bin Wu, Jiyu Cui et al.

Molecular structure elucidation involves deducing a molecule's structure from various types of spectral data, which is crucial in chemical experimental analysis. While large language models (LLMs) have shown remarkable proficiency in analyzing and reasoning through complex tasks, they still encounter substantial challenges in molecular structure elucidation. We identify that these challenges largely stem from LLMs' limited grasp of specialized chemical knowledge. In this work, we introduce a Knowledge-enhanced reasoning framework for Molecular Structure Elucidation (K-MSE), leveraging Monte Carlo Tree Search for test-time scaling as a plugin. Specifically, we construct an external molecular substructure knowledge base to extend the LLMs' coverage of the chemical structure space. Furthermore, we design a specialized molecule-spectrum scorer to act as a reward model for the reasoning process, addressing the issue of inaccurate solution evaluation in LLMs. Experimental results show that our approach significantly boosts performance, particularly gaining more than 20% improvement on both GPT-4o-mini and GPT-4o. Our code is available at https://github.com/HICAI-ZJU/K-MSE.

Haiwen Diao, Yufeng Cui, Xiaotong Li et al.

Existing vision-language models (VLMs) mostly rely on vision encoders to extract visual features followed by large language models (LLMs) for visual-language tasks. However, the vision encoders set a strong inductive bias in abstracting visual representation, e.g., resolution, aspect ratio, and semantic priors, which could impede the flexibility and efficiency of the VLMs. Training pure VLMs that accept the seamless vision and language inputs, i.e., without vision encoders, remains challenging and rarely explored. Empirical observations reveal that direct training without encoders results in slow convergence and large performance gaps. In this work, we bridge the gap between encoder-based and encoder-free models, and present a simple yet effective training recipe towards pure VLMs. Specifically, we unveil the key aspects of training encoder-free VLMs efficiently via thorough experiments: (1) Bridging vision-language representation inside one unified decoder; (2) Enhancing visual recognition capability via extra supervision. With these strategies, we launch EVE, an encoder-free vision-language model that can be trained and forwarded efficiently. Notably, solely utilizing 35M publicly accessible data, EVE can impressively rival the encoder-based VLMs of similar capacities across multiple vision-language benchmarks. It significantly outperforms the counterpart Fuyu-8B with mysterious training procedures and undisclosed training data. We believe that EVE provides a transparent and efficient route for developing a pure decoder-only architecture across modalities. Our code and models are publicly available at: https://github.com/baaivision/EVE.

Xiaotong Li, Yongxing Dai, Yixiao Ge et al.

Though remarkable progress has been achieved in various vision tasks, deep neural networks still suffer obvious performance degradation when tested in out-of-distribution scenarios. We argue that the feature statistics (mean and standard deviation), which carry the domain characteristics of the training data, can be properly manipulated to improve the generalization ability of deep learning models. Common methods often consider the feature statistics as deterministic values measured from the learned features and do not explicitly consider the uncertain statistics discrepancy caused by potential domain shifts during testing. In this paper, we improve the network generalization ability by modeling the uncertainty of domain shifts with synthesized feature statistics during training. Specifically, we hypothesize that the feature statistic, after considering the potential uncertainties, follows a multivariate Gaussian distribution. Hence, each feature statistic is no longer a deterministic value, but a probabilistic point with diverse distribution possibilities. With the uncertain feature statistics, the models can be trained to alleviate the domain perturbations and achieve better robustness against potential domain shifts. Our method can be readily integrated into networks without additional parameters. Extensive experiments demonstrate that our proposed method consistently improves the network generalization ability on multiple vision tasks, including image classification, semantic segmentation, and instance retrieval. The code can be available at https://github.com/lixiaotong97/DSU.

Zixuan Hu, Xiaotong Li, Shixiang Tang et al.

The remarkable success of pretrain-then-finetune paradigm has led to a proliferation of available pre-trained models for vision tasks. This surge presents a significant challenge in efficiently choosing the most suitable pre-trained models for downstream tasks. The critical aspect of this challenge lies in effectively predicting the model transferability by considering the underlying fine-tuning dynamics. Existing methods often model fine-tuning dynamics in feature space with linear transformations, which do not precisely align with the fine-tuning objective and fail to grasp the essential nonlinearity from optimization. To this end, we present LEAD, a finetuning-aligned approach based on the network output of logits. LEAD proposes a theoretical framework to model the optimization process and derives an ordinary differential equation (ODE) to depict the nonlinear evolution toward the final logit state. Additionally, we design a class-aware decomposition method to consider the varying evolution dynamics across classes and further ensure practical applicability. Integrating the closely aligned optimization objective and nonlinear modeling capabilities derived from the differential equation, our method offers a concise solution to effectively bridge the optimization gap in a single step, bypassing the lengthy fine-tuning process. The comprehensive experiments on 24 supervised and self-supervised pre-trained models across 10 downstream datasets demonstrate impressive performances and showcase its broad adaptability even in low-data scenarios.

Zixuan Hu, Yichun Hu, Xiaotong Li et al.

Wild Test-Time Adaptation (WTTA) is proposed to adapt a source model to unseen domains under extreme data scarcity and multiple shifts. Previous approaches mainly focused on sample selection strategies, while overlooking the fundamental problem on underlying optimization. Initially, we critically analyze the widely-adopted entropy minimization framework in WTTA and uncover its significant limitations in noisy optimization dynamics that substantially hinder adaptation efficiency. Through our analysis, we identify region confidence as a superior alternative to traditional entropy, however, its direct optimization remains computationally prohibitive for real-time applications. In this paper, we introduce a novel region-integrated method ReCAP that bypasses the lengthy process. Specifically, we propose a probabilistic region modeling scheme that flexibly captures semantic changes in embedding space. Subsequently, we develop a finite-to-infinite asymptotic approximation that transforms the intractable region confidence into a tractable and upper-bounded proxy. These innovations significantly unlock the overlooked potential dynamics in local region in a concise solution. Our extensive experiments demonstrate the consistent superiority of ReCAP over existing methods across various datasets and wild scenarios.

Venkatesh Sivaraman, Anika Vaishampayan, Xiaotong Li et al.

Temporal predictive models have the potential to improve decisions in health care, public services, and other domains, yet they often fail to effectively support decision-makers. Prior literature shows that many misalignments between model behavior and decision-makers' expectations stem from issues of model specification, namely how, when, and for whom predictions are made. However, model specifications for predictive tasks are highly technical and difficult for non-data-scientist stakeholders to interpret and critique. To address this challenge we developed Tempo, an interactive system that helps data scientists and domain experts collaboratively iterate on model specifications. Using Tempo's simple yet precise temporal query language, data scientists can quickly prototype specifications with greater transparency about pre-processing choices. Moreover, domain experts can assess performance within data subgroups to validate that models behave as expected. Through three case studies, we demonstrate how Tempo helps multidisciplinary teams quickly prune infeasible specifications and identify more promising directions to explore.

Yuhao Wang, Keyan Ding, Kehua Feng et al.

Protein language models have emerged as powerful tools for sequence generation, offering substantial advantages in functional optimization and denovo design. However, these models also present significant risks of generating harmful protein sequences, such as those that enhance viral transmissibility or evade immune responses. These concerns underscore critical biosafety and ethical challenges. To address these issues, we propose a Knowledge-guided Preference Optimization (KPO) framework that integrates prior knowledge via a Protein Safety Knowledge Graph. This framework utilizes an efficient graph pruning strategy to identify preferred sequences and employs reinforcement learning to minimize the risk of generating harmful proteins. Experimental results demonstrate that KPO effectively reduces the likelihood of producing hazardous sequences while maintaining high functionality, offering a robust safety assurance framework for applying generative models in biotechnology.

Zixuan Hu, Dongxiao Li, Xinzhu Ma et al.

Accurate monocular 3D object detection (M3OD) is pivotal for safety-critical applications like autonomous driving, yet its reliability deteriorates significantly under real-world domain shifts caused by environmental or sensor variations. To address these shifts, Test-Time Adaptation (TTA) methods have emerged, enabling models to adapt to target distributions during inference. While prior TTA approaches recognize the positive correlation between low uncertainty and high generalization ability, they fail to address the dual uncertainty inherent to M3OD: semantic uncertainty (ambiguous class predictions) and geometric uncertainty (unstable spatial localization). To bridge this gap, we propose Dual Uncertainty Optimization (DUO), the first TTA framework designed to jointly minimize both uncertainties for robust M3OD. Through a convex optimization lens, we introduce an innovative convex structure of the focal loss and further derive a novel unsupervised version, enabling label-agnostic uncertainty weighting and balanced learning for high-uncertainty objects. In parallel, we design a semantic-aware normal field constraint that preserves geometric coherence in regions with clear semantic cues, reducing uncertainty from the unstable 3D representation. This dual-branch mechanism forms a complementary loop: enhanced spatial perception improves semantic classification, and robust semantic predictions further refine spatial understanding. Extensive experiments demonstrate the superiority of DUO over existing methods across various datasets and domain shift types.

Qiang Zhang, Keyang Ding, Tianwen Lyv et al.

Large Language Models (LLMs) have emerged as a transformative power in enhancing natural language comprehension, representing a significant stride toward artificial general intelligence. The application of LLMs extends beyond conventional linguistic boundaries, encompassing specialized linguistic systems developed within various scientific disciplines. This growing interest has led to the advent of scientific LLMs, a novel subclass specifically engineered for facilitating scientific discovery. As a burgeoning area in the community of AI for Science, scientific LLMs warrant comprehensive exploration. However, a systematic and up-to-date survey introducing them is currently lacking. In this paper, we endeavor to methodically delineate the concept of "scientific language", whilst providing a thorough review of the latest advancements in scientific LLMs. Given the expansive realm of scientific disciplines, our analysis adopts a focused lens, concentrating on the biological and chemical domains. This includes an in-depth examination of LLMs for textual knowledge, small molecules, macromolecular proteins, genomic sequences, and their combinations, analyzing them in terms of model architectures, capabilities, datasets, and evaluation. Finally, we critically examine the prevailing challenges and point out promising research directions along with the advances of LLMs. By offering a comprehensive overview of technical developments in this field, this survey aspires to be an invaluable resource for researchers navigating the intricate landscape of scientific LLMs.

Yongxing Dai, Xiaotong Li, Jun Liu et al.

Domain generalizable (DG) person re-identification (ReID) is a challenging problem because we cannot access any unseen target domain data during training. Almost all the existing DG ReID methods follow the same pipeline where they use a hybrid dataset from multiple source domains for training, and then directly apply the trained model to the unseen target domains for testing. These methods often neglect individual source domains' discriminative characteristics and their relevances w.r.t. the unseen target domains, though both of which can be leveraged to help the model's generalization. To handle the above two issues, we propose a novel method called the relevance-aware mixture of experts (RaMoE), using an effective voting-based mixture mechanism to dynamically leverage source domains' diverse characteristics to improve the model's generalization. Specifically, we propose a decorrelation loss to make the source domain networks (experts) keep the diversity and discriminability of individual domains' characteristics. Besides, we design a voting network to adaptively integrate all the experts' features into the more generalizable aggregated features with domain relevance. Considering the target domains' invisibility during training, we propose a novel learning-to-learn algorithm combined with our relation alignment loss to update the voting network. Extensive experiments demonstrate that our proposed RaMoE outperforms the state-of-the-art methods.