HistDiT: A Structure-Aware Latent Conditional Diffusion Model for High-Fidelity Virtual Staining in HistopathologyAasim Bin Saleem, Amr Ahmed, Ardhendu Behera et al.
Immunohistochemistry (IHC) is essential for assessing specific immune biomarkers like Human Epidermal growth-factor Receptor 2 (HER2) in breast cancer. However, the traditional protocols of obtaining IHC stains are resource-intensive, time-consuming, and prone to structural damages. Virtual staining has emerged as a scalable alternative, but it faces significant challenges in preserving fine-grained cellular structures while accurately translating biochemical expressions. Current state-of-the-art methods still rely on Generative Adversarial Networks (GANs) or standard convolutional U-Net diffusion models that often struggle with "structure and staining trade-offs". The generated samples are either structurally relevant but blurry, or texturally realistic but have artifacts that compromise their diagnostic use. In this paper, we introduce HistDiT, a novel latent conditional Diffusion Transformer (DiT) architecture that establishes a new benchmark for visual fidelity in virtual histological staining. The novelty introduced in this work is, a) the Dual-Stream Conditioning strategy that explicitly maintains a balance between spatial constraints via VAE-encoded latents and semantic phenotype guidance via UNI embeddings; b) the multi-objective loss function that contributes to sharper images with clear morphological structure; and c) the use of the Structural Correlation Metric (SCM) to focus on the core morphological structure for precise assessment of sample quality. Consequently, our model outperforms existing baselines, as demonstrated through rigorous quantitative and qualitative evaluations.
17.3CVApr 12, 2024
IFViT: Interpretable Fixed-Length Representation for Fingerprint Matching via Vision TransformerYuhang Qiu, Honghui Chen, Xingbo Dong et al.
Determining dense feature points on fingerprints used in constructing deep fixed-length representations for accurate matching, particularly at the pixel level, is of significant interest. To explore the interpretability of fingerprint matching, we propose a multi-stage interpretable fingerprint matching network, namely Interpretable Fixed-length Representation for Fingerprint Matching via Vision Transformer (IFViT), which consists of two primary modules. The first module, an interpretable dense registration module, establishes a Vision Transformer (ViT)-based Siamese Network to capture long-range dependencies and the global context in fingerprint pairs. It provides interpretable dense pixel-wise correspondences of feature points for fingerprint alignment and enhances the interpretability in the subsequent matching stage. The second module takes into account both local and global representations of the aligned fingerprint pair to achieve an interpretable fixed-length representation extraction and matching. It employs the ViTs trained in the first module with the additional fully connected layer and retrains them to simultaneously produce the discriminative fixed-length representation and interpretable dense pixel-wise correspondences of feature points. Extensive experimental results on diverse publicly available fingerprint databases demonstrate that the proposed framework not only exhibits superior performance on dense registration and matching but also significantly promotes the interpretability in deep fixed-length representations-based fingerprint matching.
7.1LGJul 21, 2025
An Investigation of Test-time Adaptation for Audio Classification under Background NoiseWeichuang Shao, Iman Yi Liao, Tomas Henrique Bode Maul et al.
Domain shift is a prominent problem in Deep Learning, causing a model pre-trained on a source dataset to suffer significant performance degradation on test datasets. This research aims to address the issue of audio classification under domain shift caused by background noise using Test-Time Adaptation (TTA), a technique that adapts a pre-trained model during testing using only unlabelled test data before making predictions. We adopt two common TTA methods, TTT and TENT, and a state-of-the-art method CoNMix, and investigate their respective performance on two popular audio classification datasets, AudioMNIST (AM) and SpeechCommands V1 (SC), against different types of background noise and noise severity levels. The experimental results reveal that our proposed modified version of CoNMix produced the highest classification accuracy under domain shift (5.31% error rate under 10 dB exercise bike background noise and 12.75% error rate under 3 dB running tap background noise for AM) compared to TTT and TENT. The literature search provided no evidence of similar works, thereby motivating the work reported here as the first study to leverage TTA techniques for audio classification under domain shift.
1.6LGApr 25, 2021
Balancing Accuracy and Latency in Multipath Neural NetworksMohammed Amer, Tomás Maul, Iman Yi Liao
The growing capacity of neural networks has strongly contributed to their success at complex machine learning tasks and the computational demand of such large models has, in turn, stimulated a significant improvement in the hardware necessary to accelerate their computations. However, models with high latency aren't suitable for limited-resource environments such as hand-held and IoT devices. Hence, many deep learning techniques aim to address this problem by developing models with reasonable accuracy without violating the limited-resource constraint. In this work, we use a one-shot neural architecture search model to implicitly evaluate the performance of an intractable number of multipath neural networks. Combining this architecture search with a pruning technique and architecture sample evaluation, we can model the relation between the accuracy and the latency of a spectrum of models with graded complexity. We show that our method can accurately model the relative performance between models with different latencies and predict the performance of unseen models with good precision across different datasets.
2.0IVDec 30, 2020
A Review of Machine Learning Techniques for Applied Eye Fundus and Tongue Digital Image Processing with Diabetes Management SystemWei Xiang Lim, Zhiyuan Chen, Amr Ahmed et al.
Diabetes is a global epidemic and it is increasing at an alarming rate. The International Diabetes Federation (IDF) projected that the total number of people with diabetes globally may increase by 48%, from 425 million (year 2017) to 629 million (year 2045). Moreover, diabetes had caused millions of deaths and the number is increasing drastically. Therefore, this paper addresses the background of diabetes and its complications. In addition, this paper investigates innovative applications and past researches in the areas of diabetes management system with applied eye fundus and tongue digital images. Different types of existing applied eye fundus and tongue digital image processing with diabetes management systems in the market and state-of-the-art machine learning techniques from previous literature have been reviewed. The implication of this paper is to have an overview in diabetic research and what new machine learning techniques can be proposed in solving this global epidemic.