Lin Guo

Guo-qing Jiang, Jinlong Liu, Zixiang Ding et al.

As models for nature language processing (NLP), computer vision (CV) and recommendation systems (RS) require surging computation, a large number of GPUs/TPUs are paralleled as a large batch (LB) to improve training throughput. However, training such LB tasks often meets large generalization gap and downgrades final precision, which limits enlarging the batch size. In this work, we develop the variance reduced gradient descent technique (VRGD) based on the gradient signal to noise ratio (GSNR) and apply it onto popular optimizers such as SGD/Adam/LARS/LAMB. We carry out a theoretical analysis of convergence rate to explain its fast training dynamics, and a generalization analysis to demonstrate its smaller generalization gap on LB training. Comprehensive experiments demonstrate that VRGD can accelerate training ($1\sim 2 \times$), narrow generalization gap and improve final accuracy. We push the batch size limit of BERT pretraining up to 128k/64k and DLRM to 512k without noticeable accuracy loss. We improve ImageNet Top-1 accuracy at 96k by $0.52pp$ than LARS. The generalization gap of BERT and ImageNet training is significantly reduce by over $65\%$.

Lin Guo, Xiaoqing Luo, Wei Xie et al.

Existing infrared and visible image fusion methods often face the dilemma of balancing modal information. Generative fusion methods reconstruct fused images by learning from data distributions, but their generative capabilities remain limited. Moreover, the lack of interpretability in modal information selection further affects the reliability and consistency of fusion results in complex scenarios. This manuscript revisits the essence of generative image fusion under the inspiration of human cognitive laws and proposes a novel infrared and visible image fusion method, termed HCLFuse. First, HCLFuse investigates the quantification theory of information mapping in unsupervised fusion networks, which leads to the design of a multi-scale mask-regulated variational bottleneck encoder. This encoder applies posterior probability modeling and information decomposition to extract accurate and concise low-level modal information, thereby supporting the generation of high-fidelity structural details. Furthermore, the probabilistic generative capability of the diffusion model is integrated with physical laws, forming a time-varying physical guidance mechanism that adaptively regulates the generation process at different stages, thereby enhancing the ability of the model to perceive the intrinsic structure of data and reducing dependence on data quality. Experimental results show that the proposed method achieves state-of-the-art fusion performance in qualitative and quantitative evaluations across multiple datasets and significantly improves semantic segmentation metrics. This fully demonstrates the advantages of this generative image fusion method, drawing inspiration from human cognition, in enhancing structural consistency and detail quality.

Xiaoyu Fan, Lin Guo, Ruizhen Jia et al.

Artificial Intelligence (AI)-aided drug discovery is an active research field, yet AI models often exhibit poor accuracy in regression tasks for molecular property prediction, and perform catastrophically poorly for out-of-distribution (OOD) molecules. Here, we present MolRuleLoss, a substructure-substitution-rule-informed framework that improves the accuracy and generalizability of multiple molecular property regression models (MPRMs) such as GEM and UniMol for diverse molecular property prediction tasks. MolRuleLoss incorporates partial derivative constraints for substructure substitution rules (SSRs) into an MPRM's loss function. When using GEM models for predicting lipophilicity, water solubility, and solvation-free energy (using lipophilicity, ESOL, and freeSolv datasets from MoleculeNet), the root mean squared error (RMSE) values with and without MolRuleLoss were 0.587 vs. 0.660, 0.777 vs. 0.798, and 1.252 vs. 1.877, respectively, representing 2.6-33.3% performance improvements. We show that both the number and the quality of SSRs contribute to the magnitude of prediction accuracy gains obtained upon adding MolRuleLoss to an MPRM. MolRuleLoss improved the generalizability of MPRMs for "activity cliff" molecules in a lipophilicity prediction task and improved the generalizability of MPRMs for OOD molecules in a melting point prediction task. In a molecular weight prediction task for OOD molecules, MolRuleLoss reduced the RMSE value of a GEM model from 29.507 to 0.007. We also provide a formal demonstration that the upper bound of the variation for property change of SSRs is positively correlated with an MPRM's error. Together, we show that using the MolRuleLoss framework as a bolt-on boosts the prediction accuracy and generalizability of multiple MPRMs, supporting diverse applications in areas like cheminformatics and AI-aided drug discovery.

Tian He, Chen Yang, Jiawei Zhang et al.

Generative recommendation systems are increasingly adopted in local service platforms, where semantic relevance alone is insufficient without strict geographic feasibility. A key technical challenge lies in semantic ID (SID) tokenization, which directly impacts the recommendation performance. However, existing semantic codebooks neglect geographic constraints, often resulting in recommendations that are semantically relevant yet geographically unreachable. To address this limitation, we propose Pro-GEO, a Proximity-aware GEO-codebook. Pro-GEO establishes a geo-centroid local coordinate system to capture intra-cluster spatial relationships and a geo-rotary position encoding mechanism that models geographic proximity as orthogonal rotational transformations in the high-dimensional embedding. This design enables semantic and spatial signals to be jointly modeled in a balanced manner, without reducing geographic information to a weak auxiliary feature. Extensive experiments conducted on a large-scale industrial dataset reveal that Pro-GEO significantly outperforms state-of-the-art methods. In particular, Pro-GEO reduces the average geographic clustering distance by 45.60% and achieves a 1.87% improvement in Hit@50, highlighting its effectiveness for real-world local service recommendation.

Meijin Lin, Lin Guo, Dicheng Chen et al.

Objctives: This work aimed to statistically compare the metabolite quantification of human brain magnetic resonance spectroscopy (MRS) between the deep learning method QNet and the classical method LCModel through an easy-to-use intelligent cloud computing platform CloudBrain-MRS. Materials and Methods: In this retrospective study, two 3 T MRI scanners Philips Ingenia and Achieva collected 61 and 46 in vivo 1H magnetic resonance (MR) spectra of healthy participants, respectively, from the brain region of pregenual anterior cingulate cortex from September to October 2021. The analyses of Bland-Altman, Pearson correlation and reasonability were performed to assess the degree of agreement, linear correlation and reasonability between the two quantification methods. Results: Fifteen healthy volunteers (12 females and 3 males, age range: 21-35 years, mean age/standard deviation = 27.4/3.9 years) were recruited. The analyses of Bland-Altman, Pearson correlation and reasonability showed high to good consistency and very strong to moderate correlation between the two methods for quantification of total N-acetylaspartate (tNAA), total choline (tCho), and inositol (Ins) (relative half interval of limits of agreement = 3.04%, 9.3%, and 18.5%, respectively; Pearson correlation coefficient r = 0.775, 0.927, and 0.469, respectively). In addition, quantification results of QNet are more likely to be closer to the previous reported average values than those of LCModel. Conclusion: There were high or good degrees of consistency between the quantification results of QNet and LCModel for tNAA, tCho, and Ins, and QNet generally has more reasonable quantification than LCModel.

Hanyu Chen, Zhixiu Hao, Lin Guo et al.

Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer from the training-sampling discrepancy, they provide a potential solution to the problem. This study introduces a novel Cascaded Diffusion with Discrepancy Mitigation (CDDM) framework, including the low-quality image generation in latent space and the high-quality image generation in pixel space which contains data consistency and discrepancy mitigation in a one-step reconstruction process. The cascaded framework minimizes computational costs by moving some inference steps from pixel space to latent space. The discrepancy mitigation technique addresses the training-sampling gap induced by data consistency, ensuring the data distribution is close to the original manifold. A specialized Alternating Direction Method of Multipliers (ADMM) is employed to process image gradients in separate directions, offering a more targeted approach to regularization. Experimental results across two datasets demonstrate CDDM's superior performance in high-quality image generation with clearer boundaries compared to existing methods, highlighting the framework's computational efficiency.

Zixiang Ding, Guoqing Jiang, Shuai Zhang et al.

In this paper, we propose Stochastic Knowledge Distillation (SKD) to obtain compact BERT-style language model dubbed SKDBERT. In each iteration, SKD samples a teacher model from a pre-defined teacher ensemble, which consists of multiple teacher models with multi-level capacities, to transfer knowledge into student model in an one-to-one manner. Sampling distribution plays an important role in SKD. We heuristically present three types of sampling distributions to assign appropriate probabilities for multi-level teacher models. SKD has two advantages: 1) it can preserve the diversities of multi-level teacher models via stochastically sampling single teacher model in each iteration, and 2) it can also improve the efficacy of knowledge distillation via multi-level teacher models when large capacity gap exists between the teacher model and the student model. Experimental results on GLUE benchmark show that SKDBERT reduces the size of a BERT$_{\rm BASE}$ model by 40% while retaining 99.5% performances of language understanding and being 100% faster.

Zheng Gao, Lin Guo, Chi Ma et al.

Anomaly detection is facing with emerging challenges in many important industry domains, such as cyber security and online recommendation and advertising. The recent trend in these areas calls for anomaly detection on time-evolving data with high-dimensional categorical features without labeled samples. Also, there is an increasing demand for identifying and monitoring irregular patterns at multiple resolutions. In this work, we propose a unified end-to-end approach to solve these challenges by combining the advantages of Adversarial Autoencoder and Recurrent Neural Network. The model learns data representations cross different scales with attention mechanisms, on which an enhanced two-resolution anomaly detector is developed for both instances and data blocks. Extensive experiments are performed over three types of datasets to demonstrate the efficacy of our method and its superiority over the state-of-art approaches.

Lin Guo, Hui Ye, Wenbo Su et al.

Although deep learning techniques have been successfully applied to many tasks, interpreting deep neural network models is still a big challenge to us. Recently, many works have been done on visualizing and analyzing the mechanism of deep neural networks in the areas of image processing and natural language processing. In this paper, we present our approaches to visualize and understand deep neural networks for a very important commercial task--CTR (Click-through rate) prediction. We conduct experiments on the productive data from our online advertising system with daily varying distribution. To understand the mechanism and the performance of the model, we inspect the model's inner status at neuron level. Also, a probe approach is implemented to measure the layer-wise performance of the model. Moreover, to measure the influence from the input features, we calculate saliency scores based on the back-propagated gradients. Practical applications are also discussed, for example, in understanding, monitoring, diagnosing and refining models and algorithms.

Viet Ha-Thuc, Ganesh Venkataraman, Mario Rodriguez et al.

LinkedIn is the largest professional network with more than 350 million members. As the member base increases, searching for experts becomes more and more challenging. In this paper, we propose an approach to address the problem of personalized expertise search on LinkedIn, particularly for exploratory search queries containing {\it skills}. In the offline phase, we introduce a collaborative filtering approach based on matrix factorization. Our approach estimates expertise scores for both the skills that members list on their profiles as well as the skills they are likely to have but do not explicitly list. In the online phase (at query time) we use expertise scores on these skills as a feature in combination with other features to rank the results. To learn the personalized ranking function, we propose a heuristic to extract training data from search logs while handling position and sample selection biases. We tested our models on two products - LinkedIn homepage and LinkedIn recruiter. A/B tests showed significant improvements in click through rates - 31% for CTR@1 for recruiter (18% for homepage) as well as downstream messages sent from search - 37% for recruiter (20% for homepage). As of writing this paper, these models serve nearly all live traffic for skills search on LinkedIn homepage as well as LinkedIn recruiter.