Maria Drangova

Zhongwen Zhang, Dmitrii Marin, Maria Drangova et al.

We are interested in unsupervised reconstruction of complex near-capillary vasculature with thousands of bifurcations where supervision and learning are infeasible. Unsupervised methods can use many structural constraints, e.g. topology, geometry, physics. Common techniques use variants of MST on geodesic tubular graphs minimizing symmetric pairwise costs, i.e. distances. We show limitations of such standard undirected tubular graphs producing typical errors at bifurcations where flow "directedness" is critical. We introduce a new general concept of confluence for continuous oriented curves forming vessel trees and show how to enforce it on discrete tubular graphs. While confluence is a high-order property, we present an efficient practical algorithm for reconstructing confluent vessel trees using minimum arborescence on a directed graph enforcing confluence via simple flow-extrapolating arc construction. Empirical tests on large near-capillary sub-voxel vasculature volumes demonstrate significantly improved reconstruction accuracy at bifurcations. Our code has also been made publicly available.

Dmitrii Marin, Yuri Boykov, Yuchen Zhong

Many applications in vision require estimation of thin structures such as boundary edges, surfaces, roads, blood vessels, neurons, etc. Unlike most previous approaches, we simultaneously detect and delineate thin structures with sub-pixel localization and real-valued orientation estimation. This is an ill-posed problem that requires regularization. We propose an objective function combining detection likelihoods with a prior minimizing curvature of the center-lines or surfaces. Unlike simple block-coordinate descent, we develop a novel algorithm that is able to perform joint optimization of location and detection variables more effectively. Our lower bound optimization algorithm applies to quadratic or absolute curvature. The proposed early vision framework is sufficiently general and it can be used in many higher-level applications. We illustrate the advantage of our approach on a range of 2D and 3D examples.