Tianqi Xu

Preferred Networks, Kaizaburo Chubachi, Yasuhiro Fujita et al.

In this report, we introduce PLaMo 2, a series of Japanese-focused large language models featuring a hybrid Samba-based architecture that transitions to full attention via continual pre-training to support 32K token contexts. Training leverages extensive synthetic corpora to overcome data scarcity, while computational efficiency is achieved through weight reuse and structured pruning. This efficient pruning methodology produces an 8B model that achieves performance comparable to our previous 100B model. Post-training further refines the models using a pipeline of supervised fine-tuning (SFT) and direct preference optimization (DPO), enhanced by synthetic Japanese instruction data and model merging techniques. Optimized for inference using vLLM and quantization with minimal accuracy loss, the PLaMo 2 models achieve state-of-the-art results on Japanese benchmarks, outperforming similarly-sized open models in instruction-following, language fluency, and Japanese-specific knowledge.

Yuxiang Wu, Shang Wu, Xin Wang et al.

Advanced volumetric imaging methods and genetically encoded activity indicators have permitted a comprehensive characterization of whole brain activity at single neuron resolution in \textit{Caenorhabditis elegans}. The constant motion and deformation of the nematode nervous system, however, impose a great challenge for consistent identification of densely packed neurons in a behaving animal. Here, we propose a cascade solution for long-term and rapid recognition of head ganglion neurons in a freely moving \textit{C. elegans}. First, potential neuronal regions from a stack of fluorescence images are detected by a deep learning algorithm. Second, 2-dimensional neuronal regions are fused into 3-dimensional neuron entities. Third, by exploiting the neuronal density distribution surrounding a neuron and relative positional information between neurons, a multi-class artificial neural network transforms engineered neuronal feature vectors into digital neuronal identities. With a small number of training samples, our bottom-up approach is able to process each volume - $1024 \times 1024 \times 18$ in voxels - in less than 1 second and achieves an accuracy of $91\%$ in neuronal detection and above $80\%$ in neuronal tracking over a long video recording. Our work represents a step towards rapid and fully automated algorithms for decoding whole brain activity underlying naturalistic behaviors.