Ruoyu Wang

Chao Chen, Ruoyu Wang, Yuliang Guo et al.

Autonomous driving in complex urban scenarios requires 3D perception to be both comprehensive and precise. Traditional 3D perception methods focus on object detection, resulting in sparse representations that lack environmental detail. Recent approaches estimate 3D occupancy around vehicles for a more comprehensive scene representation. However, dense 3D occupancy prediction increases computational demands, challenging the balance between efficiency and resolution. High-resolution occupancy grids offer accuracy but demand substantial computational resources, while low-resolution grids are efficient but lack detail. To address this dilemma, we introduce AdaOcc, a novel adaptive-resolution, multi-modal prediction approach. Our method integrates object-centric 3D reconstruction and holistic occupancy prediction within a single framework, performing highly detailed and precise 3D reconstruction only in regions of interest (ROIs). These high-detailed 3D surfaces are represented in point clouds, thus their precision is not constrained by the predefined grid resolution of the occupancy map. We conducted comprehensive experiments on the nuScenes dataset, demonstrating significant improvements over existing methods. In close-range scenarios, we surpass previous baselines by over 13% in IOU, and over 40% in Hausdorff distance. In summary, AdaOcc offers a more versatile and effective framework for delivering accurate 3D semantic occupancy prediction across diverse driving scenarios.

Gaobin Yang, Maokui He, Shutong Niu et al.

In this paper, we propose a novel neural speaker diarization system using memory-aware multi-speaker embedding with sequence-to-sequence architecture (NSD-MS2S), which integrates a memory-aware multi-speaker embedding module with a sequence-to-sequence architecture. The system leverages a memory module to enhance speaker embeddings and employs a Seq2Seq framework to efficiently map acoustic features to speaker labels. Additionally, we explore the application of mixture of experts in speaker diarization, and introduce a Shared and Soft Mixture of Experts (SS-MoE) module to further mitigate model bias and enhance performance. Incorporating SS-MoE leads to the extended model NSD-MS2S-SSMoE. Experiments on multiple complex acoustic datasets, including CHiME-6, DiPCo, Mixer 6 and DIHARD-III evaluation sets, demonstrate meaningful improvements in robustness and generalization. The proposed methods achieve state-of-the-art results, showcasing their effectiveness in challenging real-world scenarios.

Zhenkun Shi, Qianqian Yuan, Ruoyu Wang et al.

Enzyme Commission (EC) numbers, which associate a protein sequence with the biochemical reactions it catalyzes, are essential for the accurate understanding of enzyme functions and cellular metabolism. Many ab-initio computational approaches were proposed to predict EC numbers for given input sequences directly. However, the prediction performance (accuracy, recall, precision), usability, and efficiency of existing methods still have much room to be improved. Here, we report ECRECer, a cloud platform for accurately predicting EC numbers based on novel deep learning techniques. To build ECRECer, we evaluate different protein representation methods and adopt a protein language model for protein sequence embedding. After embedding, we propose a multi-agent hierarchy deep learning-based framework to learn the proposed tasks in a multi-task manner. Specifically, we used an extreme multi-label classifier to perform the EC prediction and employed a greedy strategy to integrate and fine-tune the final model. Comparative analyses against four representative methods demonstrate that ECRECer delivers the highest performance, which improves accuracy and F1 score by 70% and 20% over the state-of-the-the-art, respectively. With ECRECer, we can annotate numerous enzymes in the Swiss-Prot database with incomplete EC numbers to their full fourth level. Take UniPort protein "A0A0U5GJ41" as an example (1.14.-.-), ECRECer annotated it with "1.14.11.38", which supported by further protein structure analysis based on AlphaFold2. Finally, we established a webserver (https://ecrecer.biodesign.ac.cn) and provided an offline bundle to improve usability.