Edward H. Herskovits

Lei Zhang, Xiaoke Wang, Michael Rawson et al.

Purpose To develop and evaluate a deep learning-based method (MC-Net) to suppress motion artifacts in brain magnetic resonance imaging (MRI). Methods MC-Net was derived from a UNet combined with a two-stage multi-loss function. T1-weighted axial brain images contaminated with synthetic motions were used to train the network. Evaluation used simulated T1 and T2-weighted axial, coronal, and sagittal images unseen during training, as well as T1-weighted images with motion artifacts from real scans. Performance indices included the peak signal to noise ratio (PSNR), structural similarity index measure (SSIM), and visual reading scores. Two clinical readers scored the images. Results The MC-Net outperformed other methods implemented in terms of PSNR and SSIM on the T1 axial test set. The MC-Net significantly improved the quality of all T1-weighted images (for all directions and for simulated as well as real motion artifacts), both on quantitative measures and visual scores. However, the MC-Net performed poorly on images of untrained contrast (T2-weighted). Conclusion The proposed two-stage multi-loss MC-Net can effectively suppress motion artifacts in brain MRI without compromising image context. Given the efficiency of the MC-Net (single image processing time ~40ms), it can potentially be used in real clinical settings. To facilitate further research, the code and trained model are available at https://github.com/MRIMoCo/DL_Motion_Correction.

Ingo Beinlich, Edward H. Herskovits

We describe an environment that considerably simplifies the process of generating Bayesian belief networks. The system has been implemented on readily available, inexpensive hardware, and provides clarity and high performance. We present an introduction to Bayesian belief networks, discuss algorithms for inference with these networks, and delineate the classes of problems that can be solved with this paradigm. We then describe the hardware and software that constitute the system, and illustrate Ergo's use with several example

Edward H. Herskovits, Gregory F. Cooper

Kutato is a system that takes as input a database of cases and produces a belief network that captures many of the dependence relations represented by those data. This system incorporates a module for determining the entropy of a belief network and a module for constructing belief networks based on entropy calculations. Kutato constructs an initial belief network in which all variables in the database are assumed to be marginally independent. The entropy of this belief network is calculated, and that arc is added that minimizes the entropy of the resulting belief network. Conditional probabilities for an arc are obtained directly from the database. This process continues until an entropy-based threshold is reached. We have tested the system by generating databases from networks using the probabilistic logic-sampling method, and then using those databases as input to Kutato. The system consistently reproduces the original belief networks with high fidelity.

Gregory F. Cooper, Edward H. Herskovits

This paper presents a Bayesian method for constructing Bayesian belief networks from a database of cases. Potential applications include computer-assisted hypothesis testing, automated scientific discovery, and automated construction of probabilistic expert systems. Results are presented of a preliminary evaluation of an algorithm for constructing a belief network from a database of cases. We relate the methods in this paper to previous work, and we discuss open problems.