Alexandre Hostettler

Loic Themyr, Clement Rambour, Nicolas Thome et al.

Transformers have proved to be very effective for visual recognition tasks. In particular, vision transformers construct compressed global representations through self-attention and learnable class tokens. Multi-resolution transformers have shown recent successes in semantic segmentation but can only capture local interactions in high-resolution feature maps. This paper extends the notion of global tokens to build GLobal Attention Multi-resolution (GLAM) transformers. GLAM is a generic module that can be integrated into most existing transformer backbones. GLAM includes learnable global tokens, which unlike previous methods can model interactions between all image regions, and extracts powerful representations during training. Extensive experiments show that GLAM-Swin or GLAM-Swin-UNet exhibit substantially better performances than their vanilla counterparts on ADE20K and Cityscapes. Moreover, GLAM can be used to segment large 3D medical images, and GLAM-nnFormer achieves new state-of-the-art performance on the BCV dataset.

Loic Themyr, Clément Rambour, Nicolas Thome et al.

Transformer models achieve state-of-the-art results for image segmentation. However, achieving long-range attention, necessary to capture global context, with high-resolution 3D images is a fundamental challenge. This paper introduces the Full resolutIoN mEmory (FINE) transformer to overcome this issue. The core idea behind FINE is to learn memory tokens to indirectly model full range interactions while scaling well in both memory and computational costs. FINE introduces memory tokens at two levels: the first one allows full interaction between voxels within local image regions (patches), the second one allows full interactions between all regions of the 3D volume. Combined, they allow full attention over high resolution images, e.g. 512 x 512 x 256 voxels and above. Experiments on the BCV image segmentation dataset shows better performances than state-of-the-art CNN and transformer baselines, highlighting the superiority of our full attention mechanism compared to recent transformer baselines, e.g. CoTr, and nnFormer.

William Ndzimbong, Cyril Fourniol, Loic Themyr et al.

Inter-modal image registration (IMIR) and image segmentation with abdominal Ultrasound (US) data has many important clinical applications, including image-guided surgery, automatic organ measurement and robotic navigation. However, research is severely limited by the lack of public datasets. We propose TRUSTED (the Tridimensional Renal Ultra Sound TomodEnsitometrie Dataset), comprising paired transabdominal 3DUS and CT kidney images from 48 human patients (96 kidneys), including segmentation, and anatomical landmark annotations by two experienced radiographers. Inter-rater segmentation agreement was over 94 (Dice score), and gold-standard segmentations were generated using the STAPLE algorithm. Seven anatomical landmarks were annotated, important for IMIR systems development and evaluation. To validate the dataset's utility, 5 competitive Deep Learning models for automatic kidney segmentation were benchmarked, yielding average DICE scores from 83.2% to 89.1% for CT, and 61.9% to 79.4% for US images. Three IMIR methods were benchmarked, and Coherent Point Drift performed best with an average Target Registration Error of 4.53mm. The TRUSTED dataset may be used freely researchers to develop and validate new segmentation and IMIR methods.

Jean-Paul Mazellier, Méline Bour-Lang, Sabrina Bourouis et al.

This technical report presents Indexity 1.4.0, a web-based tool designed for medical video annotation in surgical data science projects. We describe the main features available for the management of videos, annotations, ontology and users, as well as the global software architecture.

Patrick Bilic, Patrick Christ, Hongwei Bran Li et al.

In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper-/hypo-dense), created in collaboration with seven hospitals and research institutions. Seventy-five submitted liver and liver tumor segmentation algorithms were trained on a set of 131 computed tomography (CT) volumes and were tested on 70 unseen test images acquired from different patients. We found that not a single algorithm performed best for both liver and liver tumors in the three events. The best liver segmentation algorithm achieved a Dice score of 0.963, whereas, for tumor segmentation, the best algorithms achieved Dices scores of 0.674 (ISBI 2017), 0.702 (MICCAI 2017), and 0.739 (MICCAI 2018). Retrospectively, we performed additional analysis on liver tumor detection and revealed that not all top-performing segmentation algorithms worked well for tumor detection. The best liver tumor detection method achieved a lesion-wise recall of 0.458 (ISBI 2017), 0.515 (MICCAI 2017), and 0.554 (MICCAI 2018), indicating the need for further research. LiTS remains an active benchmark and resource for research, e.g., contributing the liver-related segmentation tasks in \url{http://medicaldecathlon.com/}. In addition, both data and online evaluation are accessible via \url{www.lits-challenge.com}.

Nader Mahmoud, Alexandre Hostettler, Toby Collins et al.

Recovering surgical scene structure in laparoscope surgery is crucial step for surgical guidance and augmented reality applications. In this paper, a quasi dense reconstruction algorithm of surgical scene is proposed. This is based on a state-of-the-art SLAM system, and is exploiting the initial exploration phase that is typically performed by the surgeon at the beginning of the surgery. We show how to convert the sparse SLAM map to a quasi dense scene reconstruction, using pairs of keyframe images and correlation-based featureless patch matching. We have validated the approach with a live porcine experiment using Computed Tomography as ground truth, yielding a Root Mean Squared Error of 4.9mm.

Nader Mahmoud, Iñigo Cirauqui, Alexandre Hostettler et al.

We aim to track the endoscope location inside the surgical scene and provide 3D reconstruction, in real-time, from the sole input of the image sequence captured by the monocular endoscope. This information offers new possibilities for developing surgical navigation and augmented reality applications. The main benefit of this approach is the lack of extra tracking elements which can disturb the surgeon performance in the clinical routine. It is our first contribution to exploit ORBSLAM, one of the best performing monocular SLAM algorithms, to estimate both of the endoscope location, and 3D structure of the surgical scene. However, the reconstructed 3D map poorly describe textureless soft organ surfaces such as liver. It is our second contribution to extend ORBSLAM to be able to reconstruct a semi-dense map of soft organs. Experimental results on in-vivo pigs, shows a robust endoscope tracking even with organs deformations and partial instrument occlusions. It also shows the reconstruction density, and accuracy against ground truth surface obtained from CT.