Mohammad Zalbagi Darestani

M. Jorge Cardoso, Wenqi Li, Richard Brown et al.

Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, well-documented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare.

Mohammad Zalbagi Darestani, Reinhard Heckel

Convolutional Neural Networks (CNNs) are highly effective for image reconstruction problems. Typically, CNNs are trained on large amounts of training images. Recently, however, un-trained CNNs such as the Deep Image Prior and Deep Decoder have achieved excellent performance for image reconstruction problems such as denoising and inpainting, \emph{without using any training data}. Motivated by this development, we address the reconstruction problem arising in accelerated MRI with un-trained neural networks. We propose a highly optimized un-trained recovery approach based on a variation of the Deep Decoder and show that it significantly outperforms other un-trained methods, in particular sparsity-based classical compressed sensing methods and naive applications of un-trained neural networks. We also compare performance (both in terms of reconstruction accuracy and computational cost) in an ideal setup for trained methods, specifically on the fastMRI dataset, where the training and test data come from the same distribution. We find that our un-trained algorithm achieves similar performance to a baseline trained neural network, but a state-of-the-art trained network outperforms the un-trained one. Finally, we perform a comparison on a non-ideal setup where the train and test distributions are slightly different, and find that our un-trained method achieves similar performance to a state-of-the-art accelerated MRI reconstruction method.