Hans Johnson

M. Jorge Cardoso, Wenqi Li, Richard Brown et al.

Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, well-documented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare.

Hans Johnson, Tianyang Fang, Alejandro Perez-Vicente et al.

We propose a distributed system based on lowpower embedded FPGAs designed for edge computing applications focused on exploring distributing scheduling optimizations for Deep Learning (DL) workloads to obtain the best performance regarding latency and power efficiency. Our cluster was modular throughout the experiment, and we have implementations that consist of up to 12 Zynq-7020 chip-based boards as well as 5 UltraScale+ MPSoC FPGA boards connected through an ethernet switch, and the cluster will evaluate configurable Deep Learning Accelerator (DLA) Versatile Tensor Accelerator (VTA). This adaptable distributed architecture is distinguished by its capacity to evaluate and manage neural network workloads in numerous configurations which enables users to conduct multiple experiments tailored to their specific application needs. The proposed system can simultaneously execute diverse Neural Network (NN) models, arrange the computation graph in a pipeline structure, and manually allocate greater resources to the most computationally intensive layers of the NN graph.

Kilian Hett, Hans Johnson, Pierrick Coupé et al.

The improvements in magnetic resonance imaging have led to the development of numerous techniques to better detect structural alterations caused by neurodegenerative diseases. Among these, the patch-based grading framework has been proposed to model local patterns of anatomical changes. This approach is attractive because of its low computational cost and its competitive performance. Other studies have proposed to analyze the deformations of brain structures using tensor-based morphometry, which is a highly interpretable approach. In this work, we propose to combine the advantages of these two approaches by extending the patch-based grading framework with a new tensor-based grading method that enables us to model patterns of local deformation using a log-Euclidean metric. We evaluate our new method in a study of the putamen for the classification of patients with pre-manifest Huntington's disease and healthy controls. Our experiments show a substantial increase in classification accuracy (87.5 $\pm$ 0.5 vs. 81.3 $\pm$ 0.6) compared to the existing patch-based grading methods, and a good complement to putamen volume, which is a primary imaging-based marker for the study of Huntington's disease.