Suhita Ghosh

Philipp Ernst, Suhita Ghosh, Georg Rose et al.

This paper proposes an extension to the Dual Branch Prior-Net for sparse view interventional CBCT reconstruction incorporating a high quality planning scan. An additional head learns to segment interventional instruments and thus guides the reconstruction task. The prior scans are misaligned by up to +-5deg in-plane during training. Experiments show that the proposed model, Dual Branch Prior-SegNet, significantly outperforms any other evaluated model by >2.8dB PSNR. It also stays robust wrt. rotations of up to +-5.5deg.

Arnab Das, Suhita Ghosh, Sebastian Stober

The detailed images produced by Magnetic Resonance Imaging (MRI) provide life-critical information for the diagnosis and treatment of prostate cancer. To provide standardized acquisition, interpretation and usage of the complex MRI images, the PI-RADS v2 guideline was proposed. An automated segmentation following the guideline facilitates consistent and precise lesion detection, staging and treatment. The guideline recommends a division of the prostate into four zones, PZ (peripheral zone), TZ (transition zone), DPU (distal prostatic urethra) and AFS (anterior fibromuscular stroma). Not every zone shares a boundary with the others and is present in every slice. Further, the representations captured by a single model might not suffice for all zones. This motivated us to design a dual-branch convolutional neural network (CNN), where each branch captures the representations of the connected zones separately. Further, the representations from different branches act complementary to each other at the second stage of training, where they are fine-tuned through an unsupervised loss. The loss penalises the difference in predictions from the two branches for the same class. We also incorporate multi-task learning in our framework to further improve the segmentation accuracy. The proposed approach improves the segmentation accuracy of the baseline (mean absolute symmetric distance) by 7.56%, 11.00%, 58.43% and 19.67% for PZ, TZ, DPU and AFS zones respectively.

Suhita Ghosh, Melanie Jouaiti, Arnab Das et al.

Speech anonymisation aims to protect speaker identity by changing personal identifiers in speech while retaining linguistic content. Current methods fail to retain prosody and unique speech patterns found in elderly and pathological speech domains, which is essential for remote health monitoring. To address this gap, we propose a voice conversion-based method (DDSP-QbE) using differentiable digital signal processing and query-by-example. The proposed method, trained with novel losses, aids in disentangling linguistic, prosodic, and domain representations, enabling the model to adapt to uncommon speech patterns. Objective and subjective evaluations show that DDSP-QbE significantly outperforms the voice conversion state-of-the-art concerning intelligibility, prosody, and domain preservation across diverse datasets, pathologies, and speakers while maintaining quality and speaker anonymity. Experts validate domain preservation by analysing twelve clinically pertinent domain attributes.

Suhita Ghosh, Yamini Sinha, Sebastian Stober

Differentiable Digital Signal Processing (DDSP) pipelines for voice conversion rely on subtractive synthesis, where a periodic excitation signal is shaped by a learned spectral envelope to reconstruct the target voice. In DDSP-QbE, the excitation is generated via phase accumulation, producing a sawtooth-like waveform whose abrupt discontinuities introduce aliasing artefacts that manifest perceptually as buzziness and spectral distortion, particularly at higher fundamental frequencies. We propose two targeted improvements to the excitation stage of the DDSP-QbE subtractive synthesizer. First, we incorporate explicit voicing detection to gate the harmonic excitation, suppressing the periodic component in unvoiced regions and replacing it with filtered noise, thereby avoiding aliased harmonic content where it is most perceptually disruptive. Second, we apply Polynomial Band-Limited Step (PolyBLEP) correction to the phase-accumulated oscillator, substituting the hard waveform discontinuity at each phase wrap with a smooth polynomial residual that cancels alias-generating components without oversampling or spectral truncation. Together, these modifications yield a cleaner harmonic roll-off, reduced high-frequency artefacts, and improved perceptual naturalness, as measured by MOS. The proposed approach is lightweight, differentiable, and integrates seamlessly into the existing DDSP-QbE training pipeline with no additional learnable parameters.

Suhita Ghosh, Melanie Jouaiti, Jan-Ole Perschewski et al.

Detecting and segmenting dysfluencies is crucial for effective speech therapy and real-time feedback. However, most methods only classify dysfluencies at the utterance level. We introduce StutterCut, a semi-supervised framework that formulates dysfluency segmentation as a graph partitioning problem, where speech embeddings from overlapping windows are represented as graph nodes. We refine the connections between nodes using a pseudo-oracle classifier trained on weak (utterance-level) labels, with its influence controlled by an uncertainty measure from Monte Carlo dropout. Additionally, we extend the weakly labelled FluencyBank dataset by incorporating frame-level dysfluency boundaries for four dysfluency types. This provides a more realistic benchmark compared to synthetic datasets. Experiments on real and synthetic datasets show that StutterCut outperforms existing methods, achieving higher F1 scores and more precise stuttering onset detection.

Suhita Ghosh, Tim Thiele, Frederic Lorbeer et al.

The increasing use of cloud-based speech assistants has heightened the need for effective speech anonymization, which aims to obscure a speaker's identity while retaining critical information for subsequent tasks. One approach to achieving this is through voice conversion. While existing methods often emphasize complex architectures and training techniques, our research underscores the importance of loss functions inspired by the human auditory system. Our proposed loss functions are model-agnostic, incorporating handcrafted and deep learning-based features to effectively capture quality representations. Through objective and subjective evaluations, we demonstrate that a VQVAE-based model, enhanced with our perception-driven losses, surpasses the vanilla model in terms of naturalness, intelligibility, and prosody while maintaining speaker anonymity. These improvements are consistently observed across various datasets, languages, target speakers, and genders.

Andre Ofner, Raihan Kabir Ratul, Suhita Ghosh et al.

There is an increasing convergence between biologically plausible computational models of inference and learning with local update rules and the global gradient-based optimization of neural network models employed in machine learning. One particularly exciting connection is the correspondence between the locally informed optimization in predictive coding networks and the error backpropagation algorithm that is used to train state-of-the-art deep artificial neural networks. Here we focus on the related, but still largely under-explored connection between precision weighting in predictive coding networks and the Natural Gradient Descent algorithm for deep neural networks. Precision-weighted predictive coding is an interesting candidate for scaling up uncertainty-aware optimization -- particularly for models with large parameter spaces -- due to its distributed nature of the optimization process and the underlying local approximation of the Fisher information metric, the adaptive learning rate that is central to Natural Gradient Descent. Here, we show that hierarchical predictive coding networks with learnable precision indeed are able to solve various supervised and unsupervised learning tasks with performance comparable to global backpropagation with natural gradients and outperform their classical gradient descent counterpart on tasks where high amounts of noise are embedded in data or label inputs. When applied to unsupervised auto-encoding of image inputs, the deterministic network produces hierarchically organized and disentangled embeddings, hinting at the close connections between predictive coding and hierarchical variational inference.

Anneke Meyer, Suhita Ghosh, Daniel Schindele et al.

Various convolutional neural network (CNN) based concepts have been introduced for the prostate's automatic segmentation and its coarse subdivision into transition zone (TZ) and peripheral zone (PZ). However, when targeting a fine-grained segmentation of TZ, PZ, distal prostatic urethra (DPU) and the anterior fibromuscular stroma (AFS), the task becomes more challenging and has not yet been solved at the level of human performance. One reason might be the insufficient amount of labeled data for supervised training. Therefore, we propose to apply a semi-supervised learning (SSL) technique named uncertainty-aware temporal self-learning (UATS) to overcome the expensive and time-consuming manual ground truth labeling. We combine the SSL techniques temporal ensembling and uncertainty-guided self-learning to benefit from unlabeled images, which are often readily available. Our method significantly outperforms the supervised baseline and obtained a Dice coefficient (DC) of up to 78.9% , 87.3%, 75.3%, 50.6% for TZ, PZ, DPU and AFS, respectively. The obtained results are in the range of human inter-rater performance for all structures. Moreover, we investigate the method's robustness against noise and demonstrate the generalization capability for varying ratios of labeled data and on other challenging tasks, namely the hippocampus and skin lesion segmentation. UATS achieved superiority segmentation quality compared to the supervised baseline, particularly for minimal amounts of labeled data.

Soumick Chatterjee, Fatima Saad, Chompunuch Sarasaen et al.

The outbreak of COVID-19 has shocked the entire world with its fairly rapid spread and has challenged different sectors. One of the most effective ways to limit its spread is the early and accurate diagnosing infected patients. Medical imaging, such as X-ray and Computed Tomography (CT), combined with the potential of Artificial Intelligence (AI), plays an essential role in supporting medical personnel in the diagnosis process. Thus, in this article five different deep learning models (ResNet18, ResNet34, InceptionV3, InceptionResNetV2 and DenseNet161) and their ensemble, using majority voting have been used to classify COVID-19, pneumoniæ and healthy subjects using chest X-ray images. Multilabel classification was performed to predict multiple pathologies for each patient, if present. Firstly, the interpretability of each of the networks was thoroughly studied using local interpretability methods - occlusion, saliency, input X gradient, guided backpropagation, integrated gradients, and DeepLIFT, and using a global technique - neuron activation profiles. The mean Micro-F1 score of the models for COVID-19 classifications ranges from 0.66 to 0.875, and is 0.89 for the ensemble of the network models. The qualitative results showed that the ResNets were the most interpretable models. This research demonstrates the importance of using interpretability methods to compare different models before making a decision regarding the best performing model.