Wentao Shi

Chenxiao Fan, Chongming Gao, Wentao Shi et al.

Accurate and safe medication recommendations are critical for effective clinical decision-making, especially in multimorbidity cases. However, existing systems rely on point-wise prediction paradigms that overlook synergistic drug effects and potential adverse drug-drug interactions (DDIs). We propose FLAME, a fine-grained list-wise alignment framework for large language models (LLMs), enabling drug-by-drug generation of drug lists. FLAME formulates recommendation as a sequential decision process, where each step adds or removes a single drug. To provide fine-grained learning signals, we devise step-wise Group Relative Policy Optimization (GRPO) with potential-based reward shaping, which explicitly models DDIs and optimizes the contribution of each drug to the overall prescription. Furthermore, FLAME enhances patient modeling by integrating structured clinical knowledge and collaborative information into the representation space of LLMs. Experiments on benchmark datasets demonstrate that FLAME achieves state-of-the-art performance, delivering superior accuracy, controllable safety-accuracy trade-offs, and strong generalization across diverse clinical scenarios. Our code is available at https://github.com/cxfann/Flame.

Moxin Li, Yuantao Zhang, Wenjie Wang et al.

Multi-Objective Alignment (MOA) aims to align LLMs' responses with multiple human preference objectives, with Direct Preference Optimization (DPO) emerging as a prominent approach. However, we find that DPO-based MOA approaches suffer from widespread preference conflicts in the data, where different objectives favor different responses. This results in conflicting optimization directions, hindering the optimization on the Pareto Front. To address this, we propose to construct Pareto-optimal responses to resolve preference conflicts. To efficiently obtain and utilize such responses, we propose a self-improving DPO framework that enables LLMs to self-generate and select Pareto-optimal responses for self-supervised preference alignment. Extensive experiments on two datasets demonstrate the superior Pareto Front achieved by our framework compared to various baselines. Code is available at https://github.com/zyttt-coder/SIPO.

Jing Xu, Wentao Shi, Sheng Ren et al.

In the field of transportation, it is of paramount importance to address and mitigate illegal actions committed by both motor and non-motor vehicles. Among those actions, wrong-way cycling (i.e., riding a bicycle or e-bike in the opposite direction of the designated traffic flow) poses significant risks to both cyclists and other road users. To this end, this paper formulates a problem of detecting wrong-way cycling ratios in CCTV videos. Specifically, we propose a sparse sampling method called WWC-Predictor to efficiently solve this problem, addressing the inefficiencies of direct tracking methods. Our approach leverages both detection-based information, which utilizes the information from bounding boxes, and orientation-based information, which provides insights into the image itself, to enhance instantaneous information capture capability. On our proposed benchmark dataset consisting of 35 minutes of video sequences and minute-level annotation, our method achieves an average error rate of a mere 1.475% while taking only 19.12% GPU time of straightforward tracking methods under the same detection model. This remarkable performance demonstrates the effectiveness of our approach in identifying and predicting instances of wrong-way cycling.