Maurizio Corbetta

Louis Fabrice Tshimanga, Manfredo Atzori, Federico Del Pup et al.

In recent years, deep learning revolutionized machine learning and its applications, producing results comparable to human experts in several domains, including neuroscience. Each year, hundreds of scientific publications present applications of deep neural networks for biomedical data analysis. Due to the fast growth of the domain, it could be a complicated and extremely time-consuming task for worldwide researchers to have a clear perspective of the most recent and advanced software libraries. This work contributes to clarify the current situation in the domain, outlining the most useful libraries that implement and facilitate deep learning application to neuroscience, allowing scientists to identify the most suitable options for their research or clinical projects. This paper summarizes the main developments in Deep Learning and their relevance to Neuroscience; it then reviews neuroinformatic toolboxes and libraries, collected from the literature and from specific hubs of software projects oriented to neuroscience research. The selected tools are presented in tables detailing key features grouped by domain of application (e.g. data type, neuroscience area, task), model engineering (e.g. programming language, model customization) and technological aspect (e.g. interface, code source). The results show that, among a high number of available software tools, several libraries are standing out in terms of functionalities for neuroscience applications. The aggregation and discussion of this information can help the neuroscience community to devolop their research projects more efficiently and quickly, both by means of readily available tools, and by knowing which modules may be improved, connected or added.

Chris Foulon, Marcela Ovando-Tellez, Lia Talozzi et al.

Understanding complex phenomena often requires analyzing high-dimensional data to uncover emergent properties that arise from multifactorial interactions. Here, we present EMUSES (Emerging-properties Mapping Using Spatial Embedding Statistics), an innovative approach employing Uniform Manifold Approximation and Projection (UMAP) to create high-dimensional embeddings that reveal latent structures within data. EMUSES facilitates the exploration and prediction of emergent properties by statistically analyzing these latent spaces. Using three distinct datasets--a handwritten digits dataset from the National Institute of Standards and Technology (NIST, E. Alpaydin, 1998), the Chicago Face Database (Ma et al., 2015), and brain disconnection data post-stroke (Talozzi et al., 2023)--we demonstrate EMUSES' effectiveness in detecting and interpreting emergent properties. Our method not only predicts outcomes with high accuracy but also provides clear visualizations and statistical insights into the underlying interactions within the data. By bridging the gap between predictive accuracy and interpretability, EMUSES offers researchers a powerful tool to understand the multifactorial origins of complex phenomena.