Yandong Yan

Yandong Yan, Chenxi Li, Yu Huang et al.

The scarcity of large-scale and high-quality electronic health records (EHRs) remains a major bottleneck in biomedical research, especially as large foundation models become increasingly data-hungry. Synthesizing substantial volumes of de-identified and high-fidelity data from existing datasets has emerged as a promising solution. However, existing methods suffer from a series of limitations: they struggle to model the intrinsic properties of heterogeneous multimodal EHR data (e.g., continuous, discrete, and textual modalities), capture the complex dependencies among them, and robustly handle pervasive data incompleteness. These challenges are particularly acute in Traditional Chinese Medicine (TCM). To this end, we propose TCDiff (Triplex Cascaded Diffusion Network), a novel EHR generation framework that cascades three diffusion networks to learn the features of real-world EHR data, formatting a multi-stage generative process: Reference Modalities Diffusion, Cross-Modal Bridging, and Target Modality Diffusion. Furthermore, to validate our proposed framework, besides two public datasets, we also construct and introduce TCM-SZ1, a novel multimodal EHR dataset for benchmarking. Experimental results show that TCDiff consistently outperforms state-of-the-art baselines by an average of 10% in data fidelity under various missing rate, while maintaining competitive privacy guarantees. This highlights the effectiveness, robustness, and generalizability of our approach in real-world healthcare scenarios.

Ziming You, Yumiao Zhang, Dexuan Xu et al.

Existing large language model (LLM) agents for automating data science show promise, but they remain constrained by narrow task scopes, limited generalization across tasks and models, and over-reliance on state-of-the-art (SOTA) LLMs. We introduce DatawiseAgent, a notebook-centric LLM agent framework for adaptive and robust data science automation. Inspired by how human data scientists work in computational notebooks, DatawiseAgent introduces a unified interaction representation and a multi-stage architecture based on finite-state transducers (FSTs). This design enables flexible long-horizon planning, progressive solution development, and robust recovery from execution failures. Extensive experiments across diverse data science scenarios and models show that DatawiseAgent consistently achieves SOTA performance by surpassing strong baselines such as AutoGen and TaskWeaver, demonstrating superior effectiveness and adaptability. Further evaluations reveal graceful performance degradation under weaker or smaller models, underscoring the robustness and scalability.