Riccardo Mengoni

Ettore Canonici, Stefano Martina, Riccardo Mengoni et al.

Neutral atoms devices represent a promising technology that uses optical tweezers to geometrically arrange atoms and modulated laser pulses to control the quantum states. A neutral atoms Noisy Intermediate Scale Quantum (NISQ) device is developed by Pasqal with rubidium atoms that will allow to work with up to 100 qubits. All NISQ devices are affected by noise that have an impact on the computations results. Therefore it is important to better understand and characterize the noise sources and possibly to correct them. Here, two approaches are proposed to characterize and correct noise parameters on neutral atoms NISQ devices. In particular the focus is on Pasqal devices and Machine Learning (ML) techniques are adopted to pursue those objectives. To characterize the noise parameters, several ML models are trained, using as input only the measurements of the final quantum state of the atoms, to predict laser intensity fluctuation and waist, temperature and false positive and negative measurement rate. Moreover, an analysis is provided with the scaling on the number of atoms in the system and on the number of measurements used as input. Also, we compare on real data the values predicted with ML with the a priori estimated parameters. Finally, a Reinforcement Learning (RL) framework is employed to design a pulse in order to correct the effect of the noise in the measurements. It is expected that the analysis performed in this work will be useful for a better understanding of the quantum dynamic in neutral atoms devices and for the widespread adoption of this class of NISQ devices.

Simone De Santis, Damiana Lazzaro, Riccardo Mengoni et al.

In this new computing paradigm, named quantum computing, researchers from all over the world are taking their first steps in designing quantum circuits for image processing, through a difficult process of knowledge transfer. This effort is named Quantum Image Processing, an emerging research field pushed by powerful parallel computing capabilities of quantum computers. This work goes in this direction and proposes the challenging development of a powerful method of image denoising, such as the Total Variation (TV) model, in a quantum environment. The proposed Quantum TV is described and its sub-components are analysed. Despite the natural limitations of the current capabilities of quantum devices, the experimental results show a competitive denoising performance compared to the classical variational TV counterpart.

Emanuele Triuzzi, Riccardo Mengoni, Francesco Micucci et al.

Molecular docking is an essential step in the drug discovery process involving the detection of three-dimensional poses of a ligand inside the active site of the protein. In this paper, we address the Molecular Docking search phase by formulating the problem in QUBO terms, suitable for an annealing approach. We propose a problem formulation as a weighted subgraph isomorphism between the ligand graph and the grid of the target protein pocket. In particular, we applied a graph representation to the ligand embedding all the geometrical properties of the molecule including its flexibility, and we created a weighted spatial grid to the 3D space region inside the pocket. Results and performance obtained with quantum annealers are compared with classical simulated annealing solvers.

Massimiliano Incudini, Fabio Tarocco, Riccardo Mengoni et al.

Distance measures provide the foundation for many popular algorithms in Machine Learning and Pattern Recognition. Different notions of distance can be used depending on the types of the data the algorithm is working on. For graph-shaped data, an important notion is the Graph Edit Distance (GED) that measures the degree of (dis)similarity between two graphs in terms of the operations needed to make them identical. As the complexity of computing GED is the same as NP-hard problems, it is reasonable to consider approximate solutions. In this paper we present a QUBO formulation of the GED problem. This allows us to implement two different approaches, namely quantum annealing and variational quantum algorithms that run on the two types of quantum hardware currently available: quantum annealer and gate-based quantum computer, respectively. Considering the current state of noisy intermediate-scale quantum computers, we base our study on proof-of-principle tests of their performance.

Riccardo Mengoni, Massimiliano Incudini, Alessandra Di Pierro

We address the problem of facial expression recognition and show a possible solution using a quantum machine learning approach. In order to define an efficient classifier for a given dataset, our approach substantially exploits quantum interference. By representing face expressions via graphs, we define a classifier as a quantum circuit that manipulates the graphs adjacency matrices encoded into the amplitudes of some appropriately defined quantum states. We discuss the accuracy of the quantum classifier evaluated on the quantum simulator available on the IBM Quantum Experience cloud platform, and compare it with the accuracy of one of the best classical classifier.

Riccardo Mengoni, Daniele Ottaviani, Paolino Iorio

The RSA cryptosystem could be easily broken with large scale general purpose quantum computers running Shor's factorization algorithm. Being such devices still in their infancy, a quantum annealing approach to integer factorization has recently gained attention. In this work, we analyzed the most promising strategies for RSA hacking via quantum annealing with an extensive study of the low noise D-Wave 2000Q computational times, current hardware limitations and challenges for future developments.