Alexandre Jacquillat

Cynthia Barnhart, Alexandre Jacquillat, Alexandria Schmid

The rapid deployment of robotics technologies requires dedicated optimization algorithms to manage large fleets of autonomous agents. This paper supports robotic parts-to-picker operations in warehousing by optimizing order-workstation assignments, item-pod assignments and the schedule of order fulfillment at workstations. The model maximizes throughput, while managing human workload at the workstations and congestion in the facility. We solve it via large-scale neighborhood search, with a novel learn-then-optimize approach to subproblem generation. The algorithm relies on an offline machine learning procedure to predict objective improvements based on subproblem features, and an online optimization model to generate a new subproblem at each iteration. In collaboration with Amazon Robotics, we show that our model and algorithm generate much stronger solutions for practical problems than state-of-the-art approaches. In particular, our solution enhances the utilization of robotic fleets by coordinating robotic tasks for human operators to pick multiple items at once, and by coordinating robotic routes to avoid congestion in the facility.

Hoon Oh, Yanhan Tang, Zong Zhang et al.

Unlike commercial ridesharing, non-commercial peer-to-peer (P2P) ridesharing has been subject to limited research -- although it can promote viable solutions in non-urban communities. This paper focuses on the core problem in P2P ridesharing: the matching of riders and drivers. We elevate users' preferences as a first-order concern and introduce novel notions of fairness and stability in P2P ridesharing. We propose algorithms for efficient matching while considering user-centric factors, including users' preferred departure time, fairness, and stability. Results suggest that fair and stable solutions can be obtained in reasonable computational times and can improve baseline outcomes based on system-wide efficiency exclusively.

Dimitris Bertsimas, Léonard Boussioux, Ryan Cory Wright et al.

The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing measures to slow the disease, at a steep economic price. We design analytical tools to support these decisions and combat the pandemic. Specifically, we propose a comprehensive data-driven approach to understand the clinical characteristics of COVID-19, predict its mortality, forecast its evolution, and ultimately alleviate its impact. By leveraging cohort-level clinical data, patient-level hospital data, and census-level epidemiological data, we develop an integrated four-step approach, combining descriptive, predictive and prescriptive analytics. First, we aggregate hundreds of clinical studies into the most comprehensive database on COVID-19 to paint a new macroscopic picture of the disease. Second, we build personalized calculators to predict the risk of infection and mortality as a function of demographics, symptoms, comorbidities, and lab values. Third, we develop a novel epidemiological model to project the pandemic's spread and inform social distancing policies. Fourth, we propose an optimization model to re-allocate ventilators and alleviate shortages. Our results have been used at the clinical level by several hospitals to triage patients, guide care management, plan ICU capacity, and re-distribute ventilators. At the policy level, they are currently supporting safe back-to-work policies at a major institution and equitable vaccine distribution planning at a major pharmaceutical company, and have been integrated into the US Center for Disease Control's pandemic forecast.