Thomas Watson

Yiping Jiao, Jeroen van der Laak, Shadi Albarqouni et al. · eth-zurich

We introduce LYSTO, the Lymphocyte Assessment Hackathon, which was held in conjunction with the MICCAI 2019 Conference in Shenzen (China). The competition required participants to automatically assess the number of lymphocytes, in particular T-cells, in histopathological images of colon, breast, and prostate cancer stained with CD3 and CD8 immunohistochemistry. Differently from other challenges setup in medical image analysis, LYSTO participants were solely given a few hours to address this problem. In this paper, we describe the goal and the multi-phase organization of the hackathon; we describe the proposed methods and the on-site results. Additionally, we present post-competition results where we show how the presented methods perform on an independent set of lung cancer slides, which was not part of the initial competition, as well as a comparison on lymphocyte assessment between presented methods and a panel of pathologists. We show that some of the participants were capable to achieve pathologist-level performance at lymphocyte assessment. After the hackathon, LYSTO was left as a lightweight plug-and-play benchmark dataset on grand-challenge website, together with an automatic evaluation platform. LYSTO has supported a number of research in lymphocyte assessment in oncology. LYSTO will be a long-lasting educational challenge for deep learning and digital pathology, it is available at https://lysto.grand-challenge.org/.

Bibek Poudel, Thomas Watson, Weizi Li

Autonomous micromobility has been attracting the attention of researchers and practitioners in recent years. A key component of many micro-transport vehicles is the DC motor, a complex dynamical system that is continuous and non-linear. Learning to quickly control the DC motor in the presence of disturbances and uncertainties is desired for various applications that require robustness and stability. Techniques to accomplish this task usually rely on a mathematical system model, which is often insufficient to anticipate the effects of time-varying and interrelated sources of non-linearities. While some model-free approaches have been successful at the task, they rely on massive interactions with the system and are trained in specialized hardware in order to fit a highly parameterized controller. In this work, we learn to steer a DC motor via sample-efficient reinforcement learning. Using data collected from hardware interactions in the real world, we additionally build a simulator to experiment with a wide range of parameters and learning strategies. With the best parameters found, we learn an effective control policy in one minute and 53 seconds on a simulation and in 10 minutes and 35 seconds on a physical system.