Hui Sun

Ziyan Huang, Haoyu Wang, Zhongying Deng et al.

Large-scale models pre-trained on large-scale datasets have profoundly advanced the development of deep learning. However, the state-of-the-art models for medical image segmentation are still small-scale, with their parameters only in the tens of millions. Further scaling them up to higher orders of magnitude is rarely explored. An overarching goal of exploring large-scale models is to train them on large-scale medical segmentation datasets for better transfer capacities. In this work, we design a series of Scalable and Transferable U-Net (STU-Net) models, with parameter sizes ranging from 14 million to 1.4 billion. Notably, the 1.4B STU-Net is the largest medical image segmentation model to date. Our STU-Net is based on nnU-Net framework due to its popularity and impressive performance. We first refine the default convolutional blocks in nnU-Net to make them scalable. Then, we empirically evaluate different scaling combinations of network depth and width, discovering that it is optimal to scale model depth and width together. We train our scalable STU-Net models on a large-scale TotalSegmentator dataset and find that increasing model size brings a stronger performance gain. This observation reveals that a large model is promising in medical image segmentation. Furthermore, we evaluate the transferability of our model on 14 downstream datasets for direct inference and 3 datasets for further fine-tuning, covering various modalities and segmentation targets. We observe good performance of our pre-trained model in both direct inference and fine-tuning. The code and pre-trained models are available at https://github.com/Ziyan-Huang/STU-Net.

Jin Ye, Junlong Cheng, Jianpin Chen et al.

Segment Anything Model (SAM) has achieved impressive results for natural image segmentation with input prompts such as points and bounding boxes. Its success largely owes to massive labeled training data. However, directly applying SAM to medical image segmentation cannot perform well because SAM lacks medical knowledge -- it does not use medical images for training. To incorporate medical knowledge into SAM, we introduce SA-Med2D-20M, a large-scale segmentation dataset of 2D medical images built upon numerous public and private datasets. It consists of 4.6 million 2D medical images and 19.7 million corresponding masks, covering almost the whole body and showing significant diversity. This paper describes all the datasets collected in SA-Med2D-20M and details how to process these datasets. Furthermore, comprehensive statistics of SA-Med2D-20M are presented to facilitate the better use of our dataset, which can help the researchers build medical vision foundation models or apply their models to downstream medical applications. We hope that the large scale and diversity of SA-Med2D-20M can be leveraged to develop medical artificial intelligence for enhancing diagnosis, medical image analysis, knowledge sharing, and education. The data with the redistribution license is publicly available at https://github.com/OpenGVLab/SAM-Med2D.

Ziyan Huang, Zhongying Deng, Jin Ye et al.

Although deep learning have revolutionized abdominal multi-organ segmentation, models often struggle with generalization due to training on small, specific datasets. With the recent emergence of large-scale datasets, some important questions arise: \textbf{Can models trained on these datasets generalize well on different ones? If yes/no, how to further improve their generalizability?} To address these questions, we introduce A-Eval, a benchmark for the cross-dataset Evaluation ('Eval') of Abdominal ('A') multi-organ segmentation. We employ training sets from four large-scale public datasets: FLARE22, AMOS, WORD, and TotalSegmentator, each providing extensive labels for abdominal multi-organ segmentation. For evaluation, we incorporate the validation sets from these datasets along with the training set from the BTCV dataset, forming a robust benchmark comprising five distinct datasets. We evaluate the generalizability of various models using the A-Eval benchmark, with a focus on diverse data usage scenarios: training on individual datasets independently, utilizing unlabeled data via pseudo-labeling, mixing different modalities, and joint training across all available datasets. Additionally, we explore the impact of model sizes on cross-dataset generalizability. Through these analyses, we underline the importance of effective data usage in enhancing models' generalization capabilities, offering valuable insights for assembling large-scale datasets and improving training strategies. The code and pre-trained models are available at \href{https://github.com/uni-medical/A-Eval}{https://github.com/uni-medical/A-Eval}.

Junlong Cheng, Jin Ye, Zhongying Deng et al.

The Segment Anything Model (SAM) represents a state-of-the-art research advancement in natural image segmentation, achieving impressive results with input prompts such as points and bounding boxes. However, our evaluation and recent research indicate that directly applying the pretrained SAM to medical image segmentation does not yield satisfactory performance. This limitation primarily arises from significant domain gap between natural images and medical images. To bridge this gap, we introduce SAM-Med2D, the most comprehensive studies on applying SAM to medical 2D images. Specifically, we first collect and curate approximately 4.6M images and 19.7M masks from public and private datasets, constructing a large-scale medical image segmentation dataset encompassing various modalities and objects. Then, we comprehensively fine-tune SAM on this dataset and turn it into SAM-Med2D. Unlike previous methods that only adopt bounding box or point prompts as interactive segmentation approach, we adapt SAM to medical image segmentation through more comprehensive prompts involving bounding boxes, points, and masks. We additionally fine-tune the encoder and decoder of the original SAM to obtain a well-performed SAM-Med2D, leading to the most comprehensive fine-tuning strategies to date. Finally, we conducted a comprehensive evaluation and analysis to investigate the performance of SAM-Med2D in medical image segmentation across various modalities, anatomical structures, and organs. Concurrently, we validated the generalization capability of SAM-Med2D on 9 datasets from MICCAI 2023 challenge. Overall, our approach demonstrated significantly superior performance and generalization capability compared to SAM.

Hui Sun, Yinan Wu, Wesley K. G. Assunção et al.

Test code is indispensable in software development, ensuring the correctness of production code and supporting maintainability. Nonetheless, errors or omissions in the test code can conceal production defects. While code review is widely adopted to assess code quality and correctness, little research has examined how test code is reviewed. Spadini et al.'s research on Gerrit (a pre-commit review model) found that test code receives significantly less discussion than production code. However, the most popular review model is currently based on pull requests (PRs), in which contributors propose changes for discussion and approval, a more negotiable and flexible model compared to Gerrit. Furthermore, GitHub Actions (GHA) has become widely used to automate pre-checks and testing, potentially impacting review practices. This leads us to explore whether Spadini et al.'s findings still hold for the PR model in the era of GHA? Our work replicates and extends their work. We focus on GitHub PRs and analyze six open-source projects. We investigate the impact of the PR model and GHA on test code review. Our results show that GitHub's PR model fosters more balanced discussions between test and production files than Gerrit, albeit with lower overall comment density. However, despite cross-project heterogeneity, GHA adoption triggered a sharp pivot toward production code. Post-GHA, for PRs involving tests, both review probability and comment density reached a median of zero. These findings reveal how evolving continuous integration pipelines can marginalize test code review. The observed decline in test-centric discussion under GHA warrants concern regarding long-term software quality. Our work also presents recommendations for stakeholders involved in the software development life cycle.

Yanxiang Zhao, Yanping Ma, Hui Sun et al.

We construct a new phase-field model for the solvation of charged molecules with a variational implicit solvent. Our phase-field free-energy functional includes the surface energy, solute-solvent van der Waals dispersion energy, and electrostatic interaction energy that is described by the Coulomb-field approximation, all coupled together self-consistently through a phase field. By introducing a new phase-field term in the description of the solute-solvent van der Waals and electrostatic interactions, we can keep the phase-field values closer to those describing the solute and solvent regions, respectively, making it more accurate in the free-energy estimate. We first prove that our phase-field functionals $Γ$-converge to the corresponding sharp-interface limit. We then develop and implement an efficient and stable numerical method to solve the resulting gradient-flow equation to obtain equilibrium conformations and their associated free energies of the underlying charged molecular system. Our numerical method combines a linear splitting scheme, spectral discretization, and exponential time differencing Runge-Kutta approximations. Applications to the solvation of single ions and a two-plate system demonstrate that our new phase-field implementation improves the previous ones by achieving the localization of the system forces near the solute-solvent interface and maintaining more robustly the desirable hyperbolic tangent profile for even larger interfacial width. This work provides a scheme to resolve the possible unphysical feature of negative values in the phase-field function found in the previous phase-field modeling (cf. H. Sun, et al. J. Chem. Phys., 2015) of charged molecules with the Poisson--Boltzmann equation for the electrostatic interaction.

Hui Sun, Long Lv, Pingping Zhang et al.

Multi-Modal Image Fusion (MMIF) aims to integrate complementary image information from different modalities to produce informative images. Previous deep learning-based MMIF methods generally adopt Convolutional Neural Networks (CNNs) or Transformers for feature extraction. However, these methods deliver unsatisfactory performances due to the limited receptive field of CNNs and the high computational cost of Transformers. Recently, Mamba has demonstrated a powerful potential for modeling long-range dependencies with linear complexity, providing a promising solution to MMIF. Unfortunately, Mamba lacks full spatial and frequency perceptions, which are very important for MMIF. Moreover, employing Image Reconstruction (IR) as an auxiliary task has been proven beneficial for MMIF. However, a primary challenge is how to leverage IR efficiently and effectively. To address the above issues, we propose a novel framework named Spatial-Frequency Enhanced Mamba Fusion (SFMFusion) for MMIF. More specifically, we first propose a three-branch structure to couple MMIF and IR, which can retain complete contents from source images. Then, we propose the Spatial-Frequency Enhanced Mamba Block (SFMB), which can enhance Mamba in both spatial and frequency domains for comprehensive feature extraction. Finally, we propose the Dynamic Fusion Mamba Block (DFMB), which can be deployed across different branches for dynamic feature fusion. Extensive experiments show that our method achieves better results than most state-of-the-art methods on six MMIF datasets. The source code is available at https://github.com/SunHui1216/SFMFusion.

Zhongying Deng, Cheng Tang, Ziyan Huang et al. · pku

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling of such medical datasets are highly challenging due to the reliance on clinical expertise and strict ethical and privacy constraints, resulting in a scarcity of large-scale unified medical datasets and hindering the development of powerful medical foundation models. In this work, we present the largest survey to date of medical image datasets, covering over 1,000 open-access datasets with a systematic catalog of their modalities, tasks, anatomies, annotations, limitations, and potential for integration. Our analysis exposes a landscape that is modest in scale, fragmented across narrowly scoped tasks, and unevenly distributed across organs and modalities, which in turn limits the utility of existing medical image datasets for developing versatile and robust medical foundation models. To turn fragmentation into scale, we propose a metadata-driven fusion paradigm (MDFP) that integrates public datasets with shared modalities or tasks, thereby transforming multiple small data silos into larger, more coherent resources. Building on MDFP, we release an interactive discovery portal that enables end-to-end, automated medical image dataset integration, and compile all surveyed datasets into a unified, structured table that clearly summarizes their key characteristics and provides reference links, offering the community an accessible and comprehensive repository. By charting the current terrain and offering a principled path to dataset consolidation, our survey provides a practical roadmap for scaling medical imaging corpora, supporting faster data discovery, more principled dataset creation, and more capable medical foundation models.

Hui Sun, Tianqing Zhu, Wenhan Chang et al.

As machine learning continues to develop, and data misuse scandals become more prevalent, individuals are becoming increasingly concerned about their personal information and are advocating for the right to remove their data. Machine unlearning has emerged as a solution to erase training data from trained machine learning models. Despite its success in classifiers, research on Generative Adversarial Networks (GANs) is limited due to their unique architecture, including a generator and a discriminator. One challenge pertains to generator unlearning, as the process could potentially disrupt the continuity and completeness of the latent space. This disruption might consequently diminish the model's effectiveness after unlearning. Another challenge is how to define a criterion that the discriminator should perform for the unlearning images. In this paper, we introduce a substitution mechanism and define a fake label to effectively mitigate these challenges. Based on the substitution mechanism and fake label, we propose a cascaded unlearning approach for both item and class unlearning within GAN models, in which the unlearning and learning processes run in a cascaded manner. We conducted a comprehensive evaluation of the cascaded unlearning technique using the MNIST and CIFAR-10 datasets. Experimental results demonstrate that this approach achieves significantly improved item and class unlearning efficiency, reducing the required time by up to 185x and 284x for the MNIST and CIFAR-10 datasets, respectively, in comparison to retraining from scratch. Notably, although the model's performance experiences minor degradation after unlearning, this reduction is negligible when dealing with a minimal number of images (e.g., 64) and has no adverse effects on downstream tasks such as classification.

Jinming Xing, Guoheng Sun, Hui Sun et al.

Spatial-temporal network traffic forecasting is a challenging task due to the complex spatial relationships and dynamic temporal patterns present in each node. Traditional regression methods are not directly applicable to such graph data. Recently, Graph Neural Networks (GNNs) have been widely used to model spatial-temporal dependencies. However, existing methods face several limitations: (1) They rely solely on a predefined spatial adjacency matrix, overlooking hidden low-level temporal information. (2) They model spatial and temporal information separately, which inevitably leads to a loss of joint dependencies, or they capture only global or local dependencies. To address these issues, we propose the \textbf{G}lobal-\textbf{L}ocal \textbf{S}patial-\textbf{T}emporal \textbf{a}ware \textbf{G}raph \textbf{AT}tention Network (GLSTaGAT). Specifically, we adopt a data-driven spatial-temporal fusion graph that incorporates low-level spatial and temporal information, serving as the foundation for further graph convolutions. The GLSTaGAT block and its pooling variant are proposed to simultaneously capture local and global spatial-temporal dependencies. Additionally, we introduce node normalization to mitigate covariance shifts, enabling a smoother training process. An encoder-only transformer is utilized to model high-level joint dependencies, and a multi-head attention prediction layer is designed for final information aggregation and prediction. Experimental results on real-world datasets demonstrate that GLSTaGAT outperforms the baselines by 32.14\% (MAE), 28.30\% (RMSE), and 20.47\% (SMAPE) on average.

Yizhou Chen, Guangda Huzhang, Anxiang Zeng et al.

In recent years, recommender systems have advanced rapidly, where embedding learning for users and items plays a critical role. A standard method learns a unique embedding vector for each user and item. However, such a method has two important limitations in real-world applications: 1) it is hard to learn embeddings that generalize well for users and items with rare interactions on their own; and 2) it may incur unbearably high memory costs when the number of users and items scales up. Existing approaches either can only address one of the limitations or have flawed overall performances. In this paper, we propose Clustered Embedding Learning (CEL) as an integrated solution to these two problems. CEL is a plug-and-play embedding learning framework that can be combined with any differentiable feature interaction model. It is capable of achieving improved performance, especially for cold users and items, with reduced memory cost. CEL enables automatic and dynamic clustering of users and items in a top-down fashion, where clustered entities jointly learn a shared embedding. The accelerated version of CEL has an optimal time complexity, which supports efficient online updates. Theoretically, we prove the identifiability and the existence of a unique optimal number of clusters for CEL in the context of nonnegative matrix factorization. Empirically, we validate the effectiveness of CEL on three public datasets and one business dataset, showing its consistently superior performance against current state-of-the-art methods. In particular, when incorporating CEL into the business model, it brings an improvement of $+0.6\%$ in AUC, which translates into a significant revenue gain; meanwhile, the size of the embedding table gets $2650$ times smaller.

Jie Ding, Hui Sun, Zhongming Wang et al.

The steady-state Poisson-Nernst-Planck (ssPNP) equations are an effective model for the description of ionic transport in ion channels. It is observed that an ion channel exhibits voltage-dependent switching between open and closed states. Different conductance states of a channel imply that the ssPNP equations probably have multiple solutions with different level of currents. We propose numerical approaches to study multiple solutions to the ssPNP equations with multiple ionic species. To find complete current-voltage (I-V ) and current-concentration (I-C) curves, we reformulate the ssPNP equations into four different boundary value problems (BVPs). Numerical continuation approaches are developed to provide good initial guesses for iteratively solving algebraic equations resulting from discretization. Numerical continuations on V , I, and boundary concentrations result in S-shaped and double S-shaped (I-V and I-C) curves for the ssPNP equations with multiple species of ions. There are five solutions to the ssPNP equations with five ionic species, when an applied voltage is given in certain intervals. Remarkably, the current through ion channels responds hysteretically to varying applied voltages and boundary concentrations, showing a memory effect. In addition, we propose a useful computational approach to locate turning points of an I-V curve. With obtained locations, we are able to determine critical threshold values for hysteresis to occur and the interval for V in which the ssPNP equations have multiple solutions. Our numerical results indicate that the developed numerical approaches have a promising potential in studying hysteretic conductance states of ion channels.

Richard Archibald, Feng Bao, Yanzhao Cao et al.

In this paper, we carry out numerical analysis to prove convergence of a novel sample-wise back-propagation method for training a class of stochastic neural networks (SNNs). The structure of the SNN is formulated as discretization of a stochastic differential equation (SDE). A stochastic optimal control framework is introduced to model the training procedure, and a sample-wise approximation scheme for the adjoint backward SDE is applied to improve the efficiency of the stochastic optimal control solver, which is equivalent to the back-propagation for training the SNN. The convergence analysis is derived with and without convexity assumption for optimization of the SNN parameters. Especially, our analysis indicates that the number of SNN training steps should be proportional to the square of the number of layers in the convex optimization case. Numerical experiments are carried out to validate the analysis results, and the performance of the sample-wise back-propagation method for training SNNs is examined by benchmark machine learning examples.

Shiyin Lu, Yang Li, Yu Xia et al.

We present Ovis2.5, a successor to Ovis2 designed for native-resolution visual perception and strong multimodal reasoning. Ovis2.5 integrates a native-resolution vision transformer that processes images at their native, variable resolutions, avoiding the degradation from fixed-resolution tiling and preserving both fine detail and global layout -- crucial for visually dense content like complex charts. To strengthen reasoning, we train the model to move beyond linear chain-of-thought and perform reflection -- including self-checking and revision. This advanced capability is exposed as an optional "thinking mode" at inference time, allowing users to trade latency for enhanced accuracy on difficult inputs. The model is trained via a comprehensive five-phase curriculum that progressively builds its skills. The process begins with foundational visual and multimodal pretraining, advances through large-scale instruction tuning, and culminates in alignment and reasoning enhancement using DPO and GRPO. To scale these upgrades efficiently, we employ multimodal data packing and hybrid parallelism, yielding a significant end-to-end speedup. We release two open-source models: Ovis2.5-9B and Ovis2.5-2B. The latter continues the "small model, big performance" philosophy of Ovis2, making it ideal for resource-constrained, on-device scenarios. On the OpenCompass multimodal leaderboard, Ovis2.5-9B averages 78.3, marking a substantial improvement over its predecessor, Ovis2-8B, and achieving state-of-the-art results among open-source MLLMs in the sub-40B parameter range; Ovis2.5-2B scores 73.9, establishing SOTA for its size. Beyond aggregate scores, Ovis2.5 achieves leading results on STEM benchmarks, exhibits strong capabilities on grounding and video tasks, and achieves open-source SOTA at its scale for complex chart analysis.

Hui Sun, Hao Luo, Feifei Wang et al.

Scanning electron microscopy (SEM) is indispensable in diverse applications ranging from microelectronics to food processing because it provides large depth-of-field images with a resolution beyond the optical diffraction limit. However, the technology requires coating conductive films on insulator samples and a vacuum environment. We use deep learning to obtain the mapping relationship between optical super-resolution (OSR) images and SEM domain images, which enables the transformation of OSR images into SEM-like large depth-of-field images. Our custom-built scanning superlens microscopy (SSUM) system, which requires neither coating samples by conductive films nor a vacuum environment, is used to acquire the OSR images with features down to ~80 nm. The peak signal-to-noise ratio (PSNR) and structural similarity index measure values indicate that the deep learning method performs excellently in image-to-image translation, with a PSNR improvement of about 0.74 dB over the optical super-resolution images. The proposed method provides a high level of detail in the reconstructed results, indicating that it has broad applicability to chip-level defect detection, biological sample analysis, forensics, and various other fields.

Zhen Zhang, Hongrui Sun, Hui Sun

Capacity attenuation is one of the most intractable issues in the current of application of the cells. The disintegration mechanism is well known to be very complex across the system. It is a great challenge to fully comprehend this process and predict the process accurately. Thus, the machine learning (ML) technology is employed to predict the specific capacity change of the cell throughout the cycle and grasp this intricate procedure. Different from the previous work, according to the WOA-ELM model proposed in this work (R2 = 0.9999871), the key factors affecting the specific capacity of the battery are determined, and the defects in the machine learning black box are overcome by the interpretable model. Their connection with the structural damage of electrode materials and battery failure during battery cycling is comprehensively explained, revealing their essentiality to battery performance, which is conducive to superior research on contemporary batteries and modification.

Yali Du, Hui Sun, Ming Li

Programs implemented in various programming languages form the foundation of software applications. To alleviate the burden of program migration and facilitate the development of software systems, automated program translation across languages has garnered significant attention. Previous approaches primarily focus on pairwise translation paradigms, learning translation between pairs of languages using bilingual parallel data. However, parallel data is difficult to collect for some language pairs, and the distribution of program semantics across languages can shift, posing challenges for pairwise program translation. In this paper, we argue that jointly learning a unified model to translate code across multiple programming languages is superior to separately learning from bilingual parallel data. We propose Variational Interaction for Multilingual Program Translation~(VIM-PT), a disentanglement-based generative approach that jointly trains a unified model for multilingual program translation across multiple languages. VIM-PT disentangles code into language-shared and language-specific features, using variational inference and interaction information with a novel lower bound, then achieves program translation through conditional generation. VIM-PT demonstrates four advantages: 1) captures language-shared information more accurately from various implementations and improves the quality of multilingual program translation, 2) mines and leverages the capability of non-parallel data, 3) addresses the distribution shift of program semantics across languages, 4) and serves as a unified model, reducing deployment complexity.

Huidong Ma, Xinyan Shi, Hui Sun et al.

While Learned Data Compression (LDC) has achieved superior compression ratios, balancing precise probability modeling with system efficiency remains challenging. Crucially, uniform single-stream architectures struggle to simultaneously capture micro-syntactic and macro-semantic features, necessitating deep serial stacking that exacerbates latency. Compounding this, heterogeneous systems are constrained by device speed mismatches, where throughput is capped by Amdahl's Law due to serial processing. To this end, we propose a Dual-Stream Multi-Scale Decoupler that disentangles local and global contexts to replace deep serial processing with shallow parallel streams, and incorporate a Hierarchical Gated Refiner for adaptive feature refinement and precise probability modeling. Furthermore, we design a Concurrent Stream-Parallel Pipeline, which overcomes systemic bottlenecks to achieve full-pipeline parallelism. Extensive experiments demonstrate that our method achieves state-of-the-art performance in both compression ratio and throughput, while maintaining the lowest latency and memory usage. The code is available at https://github.com/huidong-ma/FADE.

Hui Sun, Chang Xu, Haonan Xie et al.

LLM-driven Anomaly Detection (AD) helps enhance the understanding and explanatory abilities of anomalous behaviors in Time Series (TS). Existing methods face challenges of inadequate reasoning ability, deficient multi-turn dialogue capability, and narrow generalization. To this end, we 1) propose a multi-agent-based TS Evolution algorithm named TSEvol. On top of it, we 2) introduce the AD reasoning and multi-turn dialogue Dataset TSEData-20K and contribute the Chatbot family for AD, including ChatAD-Llama3-8B, Qwen2.5-7B, and Mistral-7B. Furthermore, 3) we propose the TS Kahneman-Tversky Optimization (TKTO) to enhance ChatAD's cross-task generalization capability. Lastly, 4) we propose a LLM-driven Learning-based AD Benchmark LLADBench to evaluate the performance of ChatAD and nine baselines across seven datasets and tasks. Our three ChatAD models achieve substantial gains, up to 34.50% in accuracy, 34.71% in F1, and a 37.42% reduction in false positives. Besides, via KTKO, our optimized ChatAD achieves competitive performance in reasoning and cross-task generalization on classification, forecasting, and imputation.

Liang Li, Jianli Zhao, Sheng Fang et al.

Hyperspectral images (HSIs) are often degraded by complex mixed noise during acquisition and transmission, making effective denoising essential for subsequent analysis. Recent hybrid approaches that bridge model-driven and data-driven paradigms have shown great promise. However, most of these approaches lack effective alternation between different priors or modules, resulting in loosely coupled regularization and insufficient exploitation of their complementary strengths. Inspired by tensor robust principal component analysis (TRPCA), we propose a novel deep unfolding network (DU-TRPCA) that enforces stage-wise alternation between two tightly integrated modules: low-rank and sparse. The low-rank module employs thresholded tensor singular value decomposition (t-SVD), providing a widely adopted convex surrogate for tensor low-rankness and has been demonstrated to effectively capture the global spatial-spectral structure of HSIs. The Top-K sparse transformer module adaptively imposes sparse constraints, directly matching the sparse regularization in TRPCA and enabling effective removal of localized outliers and complex noise. This tightly coupled architecture preserves the stage-wise alternation between low-rank approximation and sparse refinement inherent in TRPCA, while enhancing representational capacity through attention mechanisms. Extensive experiments on synthetic and real-world HSIs demonstrate that DU-TRPCA surpasses state-of-the-art methods under severe mixed noise, while offering interpretability benefits and stable denoising dynamics inspired by iterative optimization. Code is available at https://github.com/liangli97/TRPCA-Deep-Unfolding-HSI-Denoising.

Shanshan Wang, Cheng Li, Rongpin Wang et al.

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are difficult to obtain in many clinical applications. Here, we introduce Annotation-effIcient Deep lEarning (AIDE), an open-source framework to handle imperfect training datasets. Methodological analyses and empirical evaluations are conducted, and we demonstrate that AIDE surpasses conventional fully-supervised models by presenting better performance on open datasets possessing scarce or noisy annotations. We further test AIDE in a real-life case study for breast tumor segmentation. Three datasets containing 11,852 breast images from three medical centers are employed, and AIDE, utilizing 10% training annotations, consistently produces segmentation maps comparable to those generated by fully-supervised counterparts or provided by independent radiologists. The 10-fold enhanced efficiency in utilizing expert labels has the potential to promote a wide range of biomedical applications.

Huajie Chen, Tianqing Zhu, Hailin Yang et al.

Watermarking has emerged as a key defense against the misuse of machine-generated images (MGIs). Yet the robustness of these protections remains underexplored. To reveal the limits of SOTA proactive image watermarking defenses, we propose HIDE&SEEK (HS), a suite of versatile and cost-effective attacks that reliably remove embedded watermarks while preserving high visual fidelity.

Xin-Ye Li, Ren-Biao Liu, Yun-Ji Zhang et al.

Reinforcement learning (RL) from unit-test feedback has become a standard post-training recipe for improving large language models (LLMs) on code generation. However, the pass-all-tests binary reward can be sparse, yielding no learning signal on challenging problems where none of the sampled solutions passes all tests. A common remedy is to use the test-case pass rate as a surrogate reward. In this work, we study pass-rate rewards in critic-free RL for code generation (e.g., GRPO and RLOO) and report a consistent pattern across base models and algorithms: despite alleviating reward sparsity, pass-rate rewards do not reliably improve final performance over binary rewards in rigorous controlled experiments. To understand this discrepancy, we analyze reward density and the resulting gradient directions. We find that pass-rate rewards are denser, but the induced gradient updates do not consistently move probability mass toward full-pass solutions. This arises because test-case pass rate is a miscalibrated surrogate for progress toward full correctness, and partial-pass solutions within the same group can induce conflicting gradient directions that cancel out. Overall, our results suggest that, in critic-free RL, pass-rate rewards are insufficient to improve code generation and motivate reward designs that better align optimization with the goal of full correctness.

Hui Sun, Shiyin Lu, Huanyu Wang et al.

Video large language models (Video-LLMs) have made significant progress in understanding videos. However, processing multiple frames leads to lengthy visual token sequences, presenting challenges such as the limited context length cannot accommodate the entire video, and the inclusion of irrelevant frames hinders visual perception. Hence, effective frame selection is crucial. This paper emphasizes that frame selection should follow three key principles: query relevance, list-wise diversity, and sequentiality. Existing methods, such as uniform frame sampling and query-frame matching, do not capture all of these principles. Thus, we propose Markov decision determinantal point process with dynamic programming (MDP3) for frame selection, a training-free and model-agnostic method that can be seamlessly integrated into existing Video-LLMs. Our method first estimates frame similarities conditioned on the query using a conditional Gaussian kernel within the reproducing kernel Hilbert space~(RKHS). We then apply the determinantal point process~(DPP) to the similarity matrix to capture both query relevance and list-wise diversity. To incorporate sequentiality, we segment the video and apply DPP within each segment, conditioned on the preceding segment selection, modeled as a Markov decision process~(MDP) for allocating selection sizes across segments. Theoretically, MDP3 provides a \((1 - 1/e)\)-approximate solution to the NP-hard list-wise frame selection problem with pseudo-polynomial time complexity, demonstrating its efficiency. Empirically, MDP3 significantly outperforms existing methods, verifying its effectiveness and robustness.

Feng Bao, Hui Sun

This work puts forward a novel nonlinear optimal filter namely the Ensemble Schr{ö}dinger Bridge nonlinear filter. The proposed filter finds marriage of the standard prediction procedure and the diffusion generative modeling for the analysis procedure to realize one filtering step. The designed approach finds no structural model error, and it is derivative free, training free and highly parallizable. Experimental results show that the designed algorithm performs well given highly nonlinear dynamics in (mildly) high dimension up to 40 or above under a chaotic environment. It also shows better performance than classical methods such as the ensemble Kalman filter and the Particle filter in numerous tests given different level of nonlinearity. Future work will focus on extending the proposed approach to practical meteorological applications and establishing a rigorous convergence analysis.

Hui Sun, Yun-Ji Zhang, Zheng Xie et al.

Selecting LLM-generated code candidates using LLM-generated tests is challenging because the tests themselves may be incorrect. Existing methods either treat all tests equally or rely on ad-hoc heuristics to filter unreliable tests. Yet determining test correctness requires knowing which codes are correct, creating a \emph{circular dependency}. Our key insight is that we need not determine test correctness at all: \emph{test votes should rank, not merely count}. What matters is not how many codes pass a test, but whether the test can \emph{distinguish} correct from incorrect code. We break the circular dependency via leave-one-out evaluation: hold out one test, rank codes by their aggregate scores on all remaining tests, and measure whether the held-out test's pass/fail pattern agrees with this ranking. We formalize this agreement as the leave-one-out AUC~(LOO-AUC) and prove that the expected LOO-AUC is proportional to each test's ability to separate correct code from incorrect code. Building on this, we propose \textbf{ACES}~(\textbf{A}UC \textbf{C}onsist\textbf{E}ncy \textbf{S}coring) with two complementary variants: ACES-C provides closed-form weights that provably approximate the oracle in expectation under a mild assumption on average test quality; ACES-O drops this assumption and iteratively optimizes a differentiable LOO-AUC objective. Both operate solely on the binary pass matrix with negligible overhead, and achieve state-of-the-art Pass@$k$ on multiple code generation benchmarks.

Hui Sun, Yanfeng Ding, Liping Yi et al.

Learning-based lossless compressors play a crucial role in large-scale genomic database backup, storage, transmission, and management. However, their 1) inadequate compression ratio, 2) low compression \& decompression throughput, and 3) poor compression robustness limit their widespread adoption and application in both industry and academia. To solve those challenges, we propose a novel \underline{P}arallel \underline{M}ulti-\underline{K}nowledge \underline{L}earning-based \underline{C}ompressor (PMKLC) with four crucial designs: 1) We propose an automated multi-knowledge learning-based compression framework as compressors' backbone to enhance compression ratio and robustness; 2) we design a GPU-accelerated ($s$,$k$)-mer encoder to optimize compression throughput and computing resource usage; 3) we introduce data block partitioning and Step-wise Model Passing (SMP) mechanisms for parallel acceleration; 4) We design two compression modes PMKLC-S and PMKLC-M to meet the complex application scenarios, where the former runs on a resource-constrained single GPU and the latter is multi-GPU accelerated. We benchmark PMKLC-S/M and 14 baselines (7 traditional and 7 leaning-based) on 15 real-world datasets with different species and data sizes. Compared to baselines on the testing datasets, PMKLC-S/M achieve the average compression ratio improvement up to 73.609\% and 73.480\%, the average throughput improvement up to 3.036$\times$ and 10.710$\times$, respectively. Besides, PMKLC-S/M also achieve the best robustness and competitive memory cost, indicating its greater stability against datasets with different probability distribution perturbations, and its strong ability to run on memory-constrained devices.

Yali Du, Hui Sun, Ming Li

Code translation migrates codebases across programming languages. Recently, large language models (LLMs) have achieved significant advancements in software mining. However, handling the syntactic structure of source code remains a challenge. Classic syntax-aware methods depend on intricate model architectures and loss functions, rendering their integration into LLM training resource-intensive. This paper employs in-context learning (ICL), which directly integrates task exemplars into the input context, to post-incorporate code structural knowledge into pre-trained LLMs. We revisit exemplar selection in ICL from an information-theoretic perspective, proposing that list-wise selection based on information coverage is more precise and general objective than traditional methods based on combining similarity and diversity. To address the challenges of quantifying information coverage, we introduce a surrogate measure, Coverage of Abstract Syntax Tree (CAST). Furthermore, we formulate the NP-hard CAST maximization for exemplar selection and prove that it is a standard submodular maximization problem. Therefore, we propose a greedy algorithm for CAST submodular maximization, which theoretically guarantees a (1-1/e)-approximate solution in polynomial time complexity. Our method is the first training-free and model-agnostic approach to post-incorporate code structural knowledge into existing LLMs at test time. Experimental results show that our method significantly improves LLMs performance and reveals two meaningful insights: 1) Code structural knowledge can be effectively post-incorporated into pre-trained LLMs during inference, despite being overlooked during training; 2) Scaling up model size or training data does not lead to the emergence of code structural knowledge, underscoring the necessity of explicitly considering code syntactic structure.

Yali Du, San-Zhuo Xi, Hui Sun et al.

Large language models (LLMs) have demonstrated remarkable capabilities in code generation, yet they underperform on domain-specific tasks such as Computer-Aided Design (CAD) code generation due to scarce training data. In-Context Learning (ICL) offers a training-free alternative through task-specific exemplars. However, existing selection strategies prioritize similarity or point-wise diversity, often producing redundant selections that fail to satisfy the compositional requirements of complex CAD design specifications. In this work, we propose knowledge sufficiency as a principled objective for exemplar selection that aims to maximally satisfy all requirements within design specifications. To realize this objective, we introduce Design-Specification Tiling (DST), which quantifies knowledge sufficiency through a surrogate tiling ratio by extracting multi-granular design components and measuring the proportion of query components covered by selected exemplars. We demonstrate that maximizing this objective constitutes submodular maximization and provide a polynomial-time greedy algorithm with a (1-1/e)-approximation guarantee. Extensive experiments demonstrate that DST substantially improves CAD code generation quality, consistently outperforming existing exemplar selection strategies in ICL.

Hui Sun, Zheng Xie, Hao-Yuan He et al.

Unsupervised Domain Adaptation~(UDA) focuses on transferring knowledge from a labeled source domain to an unlabeled target domain, addressing the challenge of \emph{domain shift}. Significant domain shifts hinder effective knowledge transfer, leading to \emph{negative transfer} and deteriorating model performance. Therefore, mitigating negative transfer is essential. This study revisits negative transfer through the lens of causally disentangled learning, emphasizing cross-domain discriminative disagreement on non-causal environmental features as a critical factor. Our theoretical analysis reveals that overreliance on non-causal environmental features as the environment evolves can cause discriminative disagreements~(termed \emph{environmental disagreement}), thereby resulting in negative transfer. To address this, we propose Reducing Environmental Disagreement~(RED), which disentangles each sample into domain-invariant causal features and domain-specific non-causal environmental features via adversarially training domain-specific environmental feature extractors in the opposite domains. Subsequently, RED estimates and reduces environmental disagreement based on domain-specific non-causal environmental features. Experimental results confirm that RED effectively mitigates negative transfer and achieves state-of-the-art performance.

Chang Peng, Bao Yang, Meiqi Li et al.

Ground penetrating radar (GPR) has become a rapid and non-destructive solution for road subsurface distress (RSD) detection. Deep learning-based automatic RSD recognition, though ameliorating the burden of data processing, suffers from data scarcity and insufficient capability to recognize defects. In this study, a rigorously validated 3D GPR dataset containing 2134 samples of diverse types was constructed through field scanning. A novel cross-verification strategy was proposed to fully exploit the complementary abilities of region proposal networks in object recognition from different views of GPR images. The method achieves outstanding accuracy with a recall over 98.6% in field tests. The approach, integrated into an online RSD detection system, can reduce the human labor of inspection by around 90%.

Faqian Guan, Tianqing Zhu, Hui Sun et al.

Graph data contains rich node features and unique edge information, which have been applied across various domains, such as citation networks or recommendation systems. Graph Neural Networks (GNNs) are specialized for handling such data and have shown impressive performance in many applications. However, GNNs may contain of sensitive information and susceptible to privacy attacks. For example, link stealing is a type of attack in which attackers infer whether two nodes are linked or not. Previous link stealing attacks primarily relied on posterior probabilities from the target GNN model, neglecting the significance of node features. Additionally, variations in node classes across different datasets lead to different dimensions of posterior probabilities. The handling of these varying data dimensions posed a challenge in using a single model to effectively conduct link stealing attacks on different datasets. To address these challenges, we introduce Large Language Models (LLMs) to perform link stealing attacks on GNNs. LLMs can effectively integrate textual features and exhibit strong generalizability, enabling attacks to handle diverse data dimensions across various datasets. We design two distinct LLM prompts to effectively combine textual features and posterior probabilities of graph nodes. Through these designed prompts, we fine-tune the LLM to adapt to the link stealing attack task. Furthermore, we fine-tune the LLM using multiple datasets and enable the LLM to learn features from different datasets simultaneously. Experimental results show that our approach significantly enhances the performance of existing link stealing attack tasks in both white-box and black-box scenarios. Our method can execute link stealing attacks across different datasets using only a single model, making link stealing attacks more applicable to real-world scenarios.

Hui Sun, Tianqing Zhu, Zhiqiu Zhang et al.

Deep generative models have gained much attention given their ability to generate data for applications as varied as healthcare to financial technology to surveillance, and many more - the most popular models being generative adversarial networks and variational auto-encoders. Yet, as with all machine learning models, ever is the concern over security breaches and privacy leaks and deep generative models are no exception. These models have advanced so rapidly in recent years that work on their security is still in its infancy. In an attempt to audit the current and future threats against these models, and to provide a roadmap for defense preparations in the short term, we prepared this comprehensive and specialized survey on the security and privacy preservation of GANs and VAEs. Our focus is on the inner connection between attacks and model architectures and, more specifically, on five components of deep generative models: the training data, the latent code, the generators/decoders of GANs/ VAEs, the discriminators/encoders of GANs/ VAEs, and the generated data. For each model, component and attack, we review the current research progress and identify the key challenges. The paper concludes with a discussion of possible future attacks and research directions in the field.

Cheng Li, Hui Sun, Zaiyi Liu et al.

Multi-modal magnetic resonance imaging (MRI) is essential in clinics for comprehensive diagnosis and surgical planning. Nevertheless, the segmentation of multi-modal MR images tends to be time-consuming and challenging. Convolutional neural network (CNN)-based multi-modal MR image analysis commonly proceeds with multiple down-sampling streams fused at one or several layers. Although inspiring performance has been achieved, the feature fusion is usually conducted through simple summation or concatenation without optimization. In this work, we propose a supervised image fusion method to selectively fuse the useful information from different modalities and suppress the respective noise signals. Specifically, an attention block is introduced as guidance for the information selection. From the different modalities, one modality that contributes most to the results is selected as the master modality, which supervises the information selection of the other assistant modalities. The effectiveness of the proposed method is confirmed through breast mass segmentation in MR images of two modalities and better segmentation results are achieved compared to the state-of-the-art methods.

Hui Sun, Cheng Li, Boqiang Liu et al.

Mammography is one of the most commonly applied tools for early breast cancer screening. Automatic segmentation of breast masses in mammograms is essential but challenging due to the low signal-to-noise ratio and the wide variety of mass shapes and sizes. Existing methods deal with these challenges mainly by extracting mass-centered image patches manually or automatically. However, manual patch extraction is time-consuming and automatic patch extraction brings errors that could not be compensated in the following segmentation step. In this study, we propose a novel attention-guided dense-upsampling network (AUNet) for accurate breast mass segmentation in whole mammograms directly. In AUNet, we employ an asymmetrical encoder-decoder structure and propose an effective upsampling block, attention-guided dense-upsampling block (AU block). Especially, the AU block is designed to have three merits. Firstly, it compensates the information loss of bilinear upsampling by dense upsampling. Secondly, it designs a more effective method to fuse high- and low-level features. Thirdly, it includes a channel-attention function to highlight rich-information channels. We evaluated the proposed method on two publicly available datasets, CBIS-DDSM and INbreast. Compared to three state-of-the-art fully convolutional networks, AUNet achieved the best performances with an average Dice similarity coefficient of 81.8% for CBIS-DDSM and 79.1% for INbreast.

Bing Yao, Hui Sun, Xiaohui Zhang et al.

Graphical passwords (GPWs) are convenient for mobile equipments with touch screen. Topological graphic passwords (Topsnut-gpws) can be saved in computer by classical matrices and run quickly than the existing GPWs. We research Topsnut-gpws by the matching of view, since they have many advantages. We discuss: configuration matching partition, coloring/labelling matching partition, set matching partition, matching chain, etc. And, we introduce new graph labellings for enriching Topsnut-matchings and show that these labellings can be realized for trees or spanning trees of networks. In theoretical works we explore Graph Labelling Analysis, and show that every graph admits our extremal labellings and set-type labellings in graph theory. Many of the graph labellings mentioned are related with problems of set matching partitions to number theory, and yield new objects and new problems to graph theory.

Bing Yao, Hui Sun, Hongyu Wang et al.

Graphical passwords (GPWs) have been studied over 20 years. We are motivated from QR codes that can be considered GPWs, are successfully applied in today's world. However, one need such GPWs that can be use conveniently and have higher level security in information networks. We aim to GPWs for mobile devices with touch screen. No more researching papers of GPWs by means of techniques of graph theory that are already used in a wide range of scientific areas, especially, dynamic networks. Our investigation is devoted to designing new type of graphical passwords by methods of graph theory, such as various topological structures and colorings (labellings). We develop the idea of "topological structure plus number theory" in maximal planar graphs, and provide new techniques for designing new type of GPWs, and furthermore we do theoretical analysis on these new type of GPWs.