Zhixiang Lu

Zhixiang Lu, Chong Zhang, Yulong Li et al.

The vision of an inclusive World Wide Web is impeded by a severe linguistic divide, particularly for communities in low-resource regions of Southeast Asia. While large language models (LLMs) offer a potential solution for translation, their deployment in data-poor contexts faces a dual challenge: the scarcity of high-quality, culturally relevant data and the prohibitive energy costs of training on massive, noisy web corpora. To resolve the tension between digital inclusion and environmental sustainability, we introduce Sustainable Agent-Guided Expert-tuning (SAGE). This framework pioneers an energy-aware paradigm that prioritizes the "right data" over "big data". Instead of carbon-intensive training on unfiltered datasets, SAGE employs a reinforcement learning (RL) agent, optimized via Group Relative Policy Optimization (GRPO), to autonomously curate a compact training set. The agent utilizes a semantic reward signal derived from a small, expert-constructed set of community dialogues to filter out noise and cultural misalignment. We then efficiently fine-tune open-source LLMs on this curated data using Low-Rank Adaptation (LoRA). We applied SAGE to translation tasks between English and seven low-resource languages (LRLs) in Southeast Asia. Our approach establishes new state-of-the-art performance on BLEU-4 and COMET-22 metrics, effectively capturing local linguistic nuances. Crucially, SAGE surpasses baselines trained on full datasets while reducing data usage by 97.1% and training energy consumption by 95.2%. By delivering high-performance models with a minimal environmental footprint, SAGE offers a scalable and responsible pathway to bridge the digital divide in the Global South.

Zhixiang Lu, Xueyuan Deng, Yiran Liu et al.

Traditional agent-based models (ABMs) of opinion dynamics often fail to capture the psychological heterogeneity driving online polarization due to simplistic homogeneity assumptions. This limitation obscures the critical interplay between individual cognitive biases and information propagation, thereby hindering a mechanistic understanding of how ideological divides are amplified. To address this challenge, we introduce the Personality-Refracted Intelligent Simulation Model (PRISM), a hybrid framework coupling stochastic differential equations (SDE) for continuous emotional evolution with a personality-conditional partially observable Markov decision process (PC-POMDP) for discrete decision-making. In contrast to continuous trait approaches, PRISM assigns distinct Myers-Briggs Type Indicator (MBTI) based cognitive policies to multimodal large language model (MLLM) agents, initialized via data-driven priors from large-scale social media datasets. PRISM achieves superior personality consistency aligned with human ground truth, significantly outperforming standard homogeneous and Big Five benchmarks. This framework effectively replicates emergent phenomena such as rational suppression and affective resonance, offering a robust tool for analyzing complex social media ecosystems.

Zhixiang Lu, Mengqi Han, Peixin Guo et al.

Constructing high-resolution 3D geological models from sparse 1D borehole and 2D surface data is a highly ill-posed inverse problem. Traditional heuristic and implicit modeling methods fundamentally fail to capture non-linear topological discontinuities under extreme sparsity, often yielding unrealistic artifacts. Furthermore, while deep generative architectures like Diffusion Models have revolutionized continuous domains, they suffer from severe representation collapse when conditioned on sparse categorical grids. To bridge this gap, we propose 3D-GeoFlow, the first Attention-Guided Continuous Flow Matching framework tailored for sparse multimodal geological modeling. By reformulating discrete categorical generation as a simulation-free, continuous vector field regression optimized via Mean Squared Error, our model establishes stable, deterministic optimal transport paths. Crucially, we integrate 3D Attention Gates to dynamically propagate localized borehole features across the volumetric latent space, ensuring macroscopic structural coherence. To validate our framework, we curated a large-scale multimodal dataset comprising 2,200 procedurally generated 3D geological cases. Extensive out-of-distribution (OOD) evaluations demonstrate that 3D-GeoFlow achieves a paradigm shift, significantly outperforming heuristic interpolations and standard diffusion baselines.

Linxiao Li, Zhixiang Lu

As the Web transitions from static retrieval to generative interaction, the escalating environmental footprint of Large Language Models (LLMs) presents a critical sustainability challenge. Current paradigms indiscriminately apply computation-intensive strategies like Chain-of-Thought (CoT) to billions of daily queries, causing LLM overthinking, a redundancy that amplifies carbon emissions and operational barriers. This inefficiency directly undermines UN Sustainable Development Goals 13 (Climate Action) and 10 (Reduced Inequalities) by hindering equitable AI access in resource-constrained regions. To address this, we introduce EcoThink, an energy-aware adaptive inference framework designed to reconcile high-performance AI intelligence with environmental responsibility. EcoThink employs a lightweight, distillation-based router to dynamically assess query complexity, skipping unnecessary reasoning for factoid retrieval while reserving deep computation for complex logic. Extensive evaluations across 9 diverse benchmarks demonstrate that EcoThink reduces inference energy by 40.4% on average (up to 81.9% for web knowledge retrieval) without statistically significant performance loss. By mitigating algorithmic waste, EcoThink offers a scalable path toward a sustainable, inclusive, and energy-efficient generative AI Agent.

Zhixiang Lu, Jionglong Su

Multimodal Large Language Models (MLLMs) in healthcare suffer from severe confirmation bias, often hallucinating visual details to support initial, potentially erroneous diagnostic hypotheses. Existing Chain-of-Thought (CoT) approaches lack intrinsic correction mechanisms, rendering them vulnerable to error propagation. To bridge this gap, we propose Dialectic-Med, a multi-agent framework that enforces diagnostic rigor through adversarial dialectics. Unlike static consensus models, Dialectic-Med orchestrates a dynamic interplay between three role-specialized agents: a proponent that formulates diagnostic hypotheses; an opponent equipped with a novel visual falsification module that actively retrieves contradictory visual evidence to challenge the Proponent; and a mediator that resolves conflicts via a weighted consensus graph. By explicitly modeling the cognitive process of falsification, our framework guarantees that diagnostic reasoning is tightly grounded in verified visual regions. Empirical evaluations on MIMIC-CXR-VQA, VQA-RAD, and PathVQA demonstrate that Dialectic-Med not only achieves state-of-the-art performance but also fundamentally enhances the trustworthiness of the reasoning process. Beyond accuracy, our approach significantly enhances explanation faithfulness and decisively mitigates hallucinations, establishing a new standard over single-agent baselines.

Yulong Li, Jianxu Chen, Xiwei Liu et al.

Medical foundation models generate narrative explanations but cannot quantify intervention effects, detect evidence conflicts, or validate literature claims, limiting clinical auditability. We propose causal compilation, a paradigm that transforms medical evidence from narrative text into executable code. The paradigm standardizes heterogeneous research evidence into structured estimand objects, each explicitly specifying intervention contrast, effect scale, time horizon, and target population, supporting six executable causal queries: do-calculus, counterfactual reasoning, temporal trajectories, heterogeneous effects, mechanistic decomposition, and joint interventions. We instantiate this paradigm in DoAtlas-1, compiling 1,445 effect kernels from 754 studies through effect standardization, conflict-aware graph construction, and real-world validation (Human Phenotype Project, 10,000 participants). The system achieves 98.5% canonicalization accuracy and 80.5% query executability. This paradigm shifts medical AI from text generation to executable, auditable, and verifiable causal reasoning.

Zhixiang Lu, Shijie Xu, Kaicheng Yan et al.

The deployment of vision-language models (VLMs) in dermatology is hindered by the trilemma of high computational costs, extreme data scarcity, and the black-box nature of deep learning. To address these challenges, we present SkinCLIP-VL, a resource-efficient framework that adapts foundation models for trustworthy skin cancer diagnosis. Adopting a frozen perception, adaptive reasoning paradigm, we integrate a frozen CLIP encoder with a lightweight, quantized Qwen2.5-VL via low-rank adaptation (LoRA). To strictly align visual regions with clinical semantics under long-tailed distributions, we propose the Consistency-aware Focal Alignment (CFA) Loss. This objective synergizes focal re-weighting, semantic alignment, and calibration. On ISIC and Derm7pt benchmarks, SkinCLIP-VL surpasses 13B-parameter baselines by 4.3-6.2% in accuracy with 43% fewer parameters. Crucially, blinded expert evaluation and out-of-distribution testing confirm that our visually grounded rationales significantly enhance clinical trust compared to traditional saliency maps.

Chenyu Xue, Yiran Liu, Mian Zhou et al.

Medical image segmentation driven by free-text clinical instructions is a critical frontier in computer-aided diagnosis. However, existing multimodal and foundation models struggle with the semantic ambiguity of clinical reports and fail to disambiguate complex anatomical overlaps in low-contrast scans. Furthermore, fully fine-tuning these massive architectures on limited medical datasets invariably leads to severe overfitting. To address these challenges, we propose a novel Semantic-Topological Graph Reasoning (STGR) framework for language-guided pulmonary screening. Our approach elegantly synergizes the reasoning capabilities of large language models (LLaMA-3-V) with the zero-shot delineation of vision foundation models (MedSAM). Specifically, we introduce a Text-to-Vision Intent Distillation (TVID) module to extract precise diagnostic guidance. To resolve anatomical ambiguity, we formulate mask selection as a dynamic graph reasoning problem, where candidate lesions are modeled as nodes and edges capture spatial and semantic affinities. To ensure deployment feasibility, we introduce a Selective Asymmetric Fine-Tuning (SAFT) strategy that updates less than 1% of the parameters. Rigorous 5-fold cross-validation on the LIDC-IDRI and LNDb datasets demonstrates that our framework establishes a new state-of-the-art. Notably, it achieves an 81.5% Dice Similarity Coefficient (DSC) on LIDC-IDRI, outperforming leading LLM-based tools like LISA by over 5%. Crucially, our SAFT strategy acts as a powerful regularizer, yielding exceptional cross-fold stability (0.6% DSC variance) and paving the way for robust, context-aware clinical deployment.

Zhixiang Lu, Chong Zhang, Chenyu Xue et al.

Neural machine translation (NMT) from Chinese to low-resource Southeast Asian languages remains severely constrained by the extreme scarcity of clean parallel corpora and the pervasive noise in existing mined data. This chronic shortage not only impedes effective model training but also sustains a large performance gap with high-resource directions, leaving millions of speakers of languages such as Lao, Burmese, and Tagalog with persistently low-quality translation systems despite recent advances in large multilingual models. We introduce \textbf{M}ultilingual \textbf{E}xpert-\textbf{R}eward \textbf{I}nformed \textbf{T}uning (\textbf{MERIT}), a unified translation framework that transforms the traditional English-centric ALT benchmark into a Chinese-centric evaluation suite for five Southeast Asian low-resource languages (LRLs). Our framework combines language-specific token prefixing (LTP) with supervised fine-tuning (SFT) and a novel group relative policy optimization (GRPO) guided by the semantic alignment reward (SAR). These results confirm that, in LRL{\textrightarrow}Chinese translation, targeted data curation and reward-guided optimization dramatically outperform mere model scaling.

Yuxuan Zhang, Yulong Li, Zichen Yu et al.

Long-sequence causal reasoning seeks to uncover causal relationships within extended time series data but is hindered by complex dependencies and the challenges of validating causal links. To address the limitations of large-scale language models (e.g., GPT-4) in capturing intricate emotional causality within extended dialogues, we propose CauseMotion, a long-sequence emotional causal reasoning framework grounded in Retrieval-Augmented Generation (RAG) and multimodal fusion. Unlike conventional methods relying only on textual information, CauseMotion enriches semantic representations by incorporating audio-derived features-vocal emotion, emotional intensity, and speech rate-into textual modalities. By integrating RAG with a sliding window mechanism, it effectively retrieves and leverages contextually relevant dialogue segments, thus enabling the inference of complex emotional causal chains spanning multiple conversational turns. To evaluate its effectiveness, we constructed the first benchmark dataset dedicated to long-sequence emotional causal reasoning, featuring dialogues with over 70 turns. Experimental results demonstrate that the proposed RAG-based multimodal integrated approach, the efficacy of substantially enhances both the depth of emotional understanding and the causal inference capabilities of large-scale language models. A GLM-4 integrated with CauseMotion achieves an 8.7% improvement in causal accuracy over the original model and surpasses GPT-4o by 1.2%. Additionally, on the publicly available DiaASQ dataset, CauseMotion-GLM-4 achieves state-of-the-art results in accuracy, F1 score, and causal reasoning accuracy.

Tao Tang, Shijie Xu, Yiting Wu et al.

The clinical utility of deep learning models for medical image segmentation is severely constrained by their inability to generalize to unseen domains. This failure is often rooted in the models learning spurious correlations between anatomical content and domain-specific imaging styles. To overcome this fundamental challenge, we introduce Causal-SAM-LLM, a novel framework that elevates Large Language Models (LLMs) to the role of causal reasoners. Our framework, built upon a frozen Segment Anything Model (SAM) encoder, incorporates two synergistic innovations. First, Linguistic Adversarial Disentanglement (LAD) employs a Vision-Language Model to generate rich, textual descriptions of confounding image styles. By training the segmentation model's features to be contrastively dissimilar to these style descriptions, it learns a representation robustly purged of non-causal information. Second, Test-Time Causal Intervention (TCI) provides an interactive mechanism where an LLM interprets a clinician's natural language command to modulate the segmentation decoder's features in real-time, enabling targeted error correction. We conduct an extensive empirical evaluation on a composite benchmark from four public datasets (BTCV, CHAOS, AMOS, BraTS), assessing generalization under cross-scanner, cross-modality, and cross-anatomy settings. Causal-SAM-LLM establishes a new state of the art in out-of-distribution (OOD) robustness, improving the average Dice score by up to 6.2 points and reducing the Hausdorff Distance by 15.8 mm over the strongest baseline, all while using less than 9% of the full model's trainable parameters. Our work charts a new course for building robust, efficient, and interactively controllable medical AI systems.

Yulong Li, Zhixiang Lu, Feilong Tang et al.

The rapid development of social media has significantly reshaped the dynamics of public opinion, resulting in complex interactions that traditional models fail to effectively capture. To address this challenge, we propose an innovative approach that integrates multi-dimensional Hawkes processes with Graph Neural Network, modeling opinion propagation dynamics among nodes in a social network while considering the intricate hierarchical relationships between comments. The extended multi-dimensional Hawkes process captures the hierarchical structure, multi-dimensional interactions, and mutual influences across different topics, forming a complex propagation network. Moreover, recognizing the lack of high-quality datasets capable of comprehensively capturing the evolution of public opinion dynamics, we introduce a new dataset, VISTA. It includes 159 trending topics, corresponding to 47,207 posts, 327,015 second-level comments, and 29,578 third-level comments, covering diverse domains such as politics, entertainment, sports, health, and medicine. The dataset is annotated with detailed sentiment labels across 11 categories and clearly defined hierarchical relationships. When combined with our method, it offers strong interpretability by linking sentiment propagation to the comment hierarchy and temporal evolution. Our approach provides a robust baseline for future research.

Zhixiang Lu, Yulong Li, Feilong Tang et al.

Large-scale tuberculosis (TB) screening is limited by the high cost and operational complexity of traditional diagnostics, creating a need for artificial-intelligence solutions. We propose DeepGB-TB, a non-invasive system that instantly assigns TB risk scores using only cough audio and basic demographic data. The model couples a lightweight one-dimensional convolutional neural network for audio processing with a gradient-boosted decision tree for tabular features. Its principal innovation is a Cross-Modal Bidirectional Cross-Attention module (CM-BCA) that iteratively exchanges salient cues between modalities, emulating the way clinicians integrate symptoms and risk factors. To meet the clinical priority of minimizing missed cases, we design a Tuberculosis Risk-Balanced Loss (TRBL) that places stronger penalties on false-negative predictions, thereby reducing high-risk misclassifications. DeepGB-TB is evaluated on a diverse dataset of 1,105 patients collected across seven countries, achieving an AUROC of 0.903 and an F1-score of 0.851, representing a new state of the art. Its computational efficiency enables real-time, offline inference directly on common mobile devices, making it ideal for low-resource settings. Importantly, the system produces clinically validated explanations that promote trust and adoption by frontline health workers. By coupling AI innovation with public-health requirements for speed, affordability, and reliability, DeepGB-TB offers a tool for advancing global TB control.

Yulong Li, Yuxuan Zhang, Feilong Tang et al.

Sign language is the primary communication mode for 72 million hearing-impaired individuals worldwide, necessitating effective bidirectional Sign Language Production and Sign Language Translation systems. However, functional bidirectional systems require a unified linguistic environment, hindered by the lack of suitable unified datasets, particularly those providing the necessary pose information for accurate Sign Language Production (SLP) evaluation. Concurrently, current SLP evaluation methods like back-translation ignore pose accuracy, and high-quality coordinated generation remains challenging. To create this crucial environment and overcome these challenges, we introduce CNText2Sign and CNSign, which together constitute the first unified dataset aimed at supporting bidirectional accessibility systems for Chinese sign language; CNText2Sign provides 15,000 natural language-to-sign mappings and standardized skeletal keypoints for 8,643 vocabulary items supporting pose assessment. Building upon this foundation, we propose the AuraLLM model, which leverages a decoupled architecture with CNText2Sign's pose data for novel direct gesture accuracy assessment. The model employs retrieval augmentation and Cascading Vocabulary Resolution to handle semantic mapping and out-of-vocabulary words and achieves all-scenario production with controllable coordination of gestures and facial expressions via pose-conditioned video synthesis. Concurrently, our Sign Language Translation model SignMST-C employs targeted self-supervised pretraining for dynamic feature capture, achieving new SOTA results on PHOENIX2014-T with BLEU-4 scores up to 32.08. AuraLLM establishes a strong performance baseline on CNText2Sign with a BLEU-4 score of 50.41 under direct evaluation.