Hannah Kniesel

Hannah Kniesel, Timo Ropinski, Tim Bergner et al.

Scanning Transmission Electron Microscopes (STEMs) acquire 2D images of a 3D sample on the scale of individual cell components. Unfortunately, these 2D images can be too noisy to be fused into a useful 3D structure and facilitating good denoisers is challenging due to the lack of clean-noisy pairs. Additionally, representing a detailed 3D structure can be difficult even for clean data when using regular 3D grids. Addressing these two limitations, we suggest a differentiable image formation model for STEM, allowing to learn a joint model of 2D sensor noise in STEM together with an implicit 3D model. We show, that the combination of these models are able to successfully disentangle 3D signal and noise without supervision and outperform at the same time several baselines on synthetic and real data.

Sebastian Hartwig, Dominik Engel, Leon Sick et al.

AI-based text-to-image models do not only excel at generating realistic images, they also give designers more and more fine-grained control over the image content. Consequently, these approaches have gathered increased attention within the computer graphics research community, which has been historically devoted towards traditional rendering techniques, that offer precise control over scene parameters (e.g., objects, materials, and lighting). While the quality of conventionally rendered images is assessed through well established image quality metrics, such as SSIM or PSNR, the unique challenges of text-to-image generation require other, dedicated quality metrics. These metrics must be able to not only measure overall image quality, but also how well images reflect given text prompts, whereby the control of scene and rendering parameters is interweaved. Within this survey, we provide a comprehensive overview of such text-to-image quality metrics, and propose a taxonomy to categorize these metrics. Our taxonomy is grounded in the assumption, that there are two main quality criteria, namely compositional quality and general quality, that contribute to the overall image quality. Besides the metrics, this survey covers dedicated text-to-image benchmark datasets, over which the metrics are frequently computed. Finally, we identify limitations and open challenges in the field of text-to-image generation, and derive guidelines for practitioners conducting text-to-image evaluation.

Hannah Kniesel, Leon Sick, Tristan Payer et al.

Current state-of-the-art methods for object detection rely on annotated bounding boxes of large data sets for training. However, obtaining such annotations is expensive and can require up to hundreds of hours of manual labor. This poses a challenge, especially since such annotations can only be provided by experts, as they require knowledge about the scientific domain. To tackle this challenge, we propose a domain-specific weakly supervised object detection algorithm that only relies on image-level annotations, which are significantly easier to acquire. Our method distills the knowledge of a pre-trained model, on the task of predicting the presence or absence of a virus in an image, to obtain a set of pseudo-labels that can be used to later train a state-of-the-art object detection model. To do so, we use an optimization approach with a shrinking receptive field to extract virus particles directly without specific network architectures. Through a set of extensive studies, we show how the proposed pseudo-labels are easier to obtain, and, more importantly, are able to outperform other existing weak labeling methods, and even ground truth labels, in cases where the time to obtain the annotation is limited.

Hannah Kniesel, Pedro Hermosilla, Timo Ropinski

Recent advances in conditional image generation from diffusion models have shown great potential in achieving impressive image quality while preserving the constraints introduced by the user. In particular, ControlNet enables precise alignment between ground truth segmentation masks and the generated image content, allowing the enhancement of training datasets in segmentation tasks. This raises a key question: Can ControlNet additionally be guided to generate the most informative synthetic samples for a specific task? Inspired by active learning, where the most informative real-world samples are selected based on sample difficulty or model uncertainty, we propose the first approach to integrate active learning-based selection metrics into the backward diffusion process for sample generation. Specifically, we explore uncertainty, query by committee, and expected model change, which are commonly used in active learning, and demonstrate their application for guiding the sample generation process through gradient approximation. Our method is training-free, modifying only the backward diffusion process, allowing it to be used on any pretrained ControlNet. Using this process, we show that segmentation models trained with guided synthetic data outperform those trained on non-guided synthetic data. Our work underscores the need for advanced control mechanisms for diffusion-based models, which are not only aligned with image content but additionally downstream task performance, highlighting the true potential of synthetic data generation.