Vincent Magnotta

Yan Chen, James H. Holmes, Curtis Corum et al.

Recent quantitative parameter mapping methods including MR fingerprinting (MRF) collect a time series of images that capture the evolution of magnetization. The focus of this work is to introduce a novel approach termed as Deep Factor Model(DFM), which offers an efficient representation of the multi-contrast image time series. The higher efficiency of the representation enables the acquisition of the images in a highly undersampled fashion, which translates to reduced scan time in 3D high-resolution multi-contrast applications. The approach integrates motion estimation and compensation, making the approach robust to subject motion during the scan.

Arvind Balachandrasekaran, Vincent Magnotta, Mathews Jacob

We introduce a structured low rank matrix completion algorithm to recover a series of images from their under-sampled measurements, where the signal along the parameter dimension at every pixel is described by a linear combination of exponentials. We exploit the exponential behavior of the signal at every pixel, along with the spatial smoothness of the exponential parameters to derive an annihilation relation in the Fourier domain. This relation translates to a low-rank property on a structured matrix constructed from the Fourier samples. We enforce the low rank property of the structured matrix as a regularization prior to recover the images. Since the direct use of current low rank matrix recovery schemes to this problem is associated with high computational complexity and memory demand, we adopt an iterative re-weighted least squares (IRLS) algorithm, which facilitates the exploitation of the convolutional structure of the matrix. Novel approximations involving two dimensional Fast Fourier Transforms (FFT) are introduced to drastically reduce the memory demand and computational complexity, which facilitates the extension of structured low rank methods to large scale three dimensional problems. We demonstrate our algorithm in the MR parameter mapping setting and show improvement over the state-of-the-art methods.