Zijie Yang

Junshu Pan, Panzhong Lu, Yixuan Weng et al.

Recent advances in artificial intelligence (AI) have accelerated the growth of both human-authored and AI-generated research outputs, placing increasing strain on traditional academic publishing systems and challenging the scalability of conference- and journal-centered paradigms amid rising submission volumes, reviewer workload, and venue size. To address these challenges, we explore an AI-era publishing paradigm in which both human and AI scientists participate as authors and readers, and papers evolve through continuous, feedback-driven iteration. We propose AiraXiv, an AI-driven open-access platform built on open preprints, AI-augmented analysis and review, and reader feedback. AiraXiv supports human scientists through an interactive UI and AI scientists through Model Context Protocol (MCP)-based interactions. We validate AiraXiv through real-world deployments, including serving as the submission platform for ICAIS 2025, demonstrating its potential as a fast, inclusive, and scalable research infrastructure for the AI era. AiraXiv is publicly available at https://airaxiv.com.

Yixiang Zhu, Yonghao Chen, Rui Meng et al.

Vision-Language-Action (VLA) policies are typically deployed with asynchronous inference: the robot executes a previously predicted action chunk while the model computes the next one. This creates a prediction-execution misalignment: the chunk is conditioned on the observation taken before inference began, but executes in a physical state that has already drifted forward by several control steps; naive asynchronous rollover collapses from 89% to under 1% on Kinetix as the inference cycle covers up to seven control steps. We introduce DEFLECT, a fully offline post-training refinement that applies as a near drop-in upgrade to existing async-VLA stacks by converting latency itself into a label-free preference signal: counterfactual fresh/stale action pairs are constructed from a frozen reference policy and scored under the deployment-time conditioning via an implicit flow-matching likelihood-ratio surrogate, with no human labels, reward models, or online rollouts. DEFLECT substantially extends the usable delay envelope of async VLA control, with +6.4 success-rate gain in the high-latency regime (5-7 control steps), +4.6 when transferred to a real-scale VLA at the longest delay, and consistent improvements on two real-robot tasks (a bimanual conveyor pick-and-place and a reactive whack-a-mole).

Qiujie Xie, Yixuan Weng, Minjun Zhu et al.

The emergence of large language models (LLMs) is propelling automated scientific discovery to the next level, with LLM-based Artificial Intelligence (AI) Scientist systems now taking the lead in scientific research. Several influential works have already appeared in the field of AI Scientist systems, with AI-generated research papers having been accepted at the ICLR 2025 workshop, suggesting that a human-level AI Scientist capable of uncovering phenomena previously unknown to humans, may soon become a reality. In this survey, we focus on the central question: How far are AI scientists from changing the world and reshaping the scientific research paradigm? To answer this question, we provide a prospect-driven review that comprehensively analyzes the current achievements of AI Scientist systems, identifying key bottlenecks and the critical components required for the emergence of a scientific agent capable of producing ground-breaking discoveries that solve grand challenges. We hope this survey will contribute to a clearer understanding of limitations of current AI Scientist systems, showing where we are, what is missing, and what the ultimate goals for scientific AI should be.

Zijie Yang, Yongjing Yin, Chaojun Kong et al.

Natural Medicinal Materials (NMMs) have a long history of global clinical applications and a wealth of records and knowledge. Although NMMs are a major source for drug discovery and clinical application, the utilization and sharing of NMM knowledge face crucial challenges, including the standardized description of critical information, efficient curation and acquisition, and language barriers. To address these, we developed ShennongAlpha, an AI-driven sharing and collaboration platform for intelligent knowledge curation, acquisition, and translation. For standardized knowledge curation, the platform introduced a Systematic Nomenclature to enable accurate differentiation and identification of NMMs. More than fourteen thousand Chinese NMMs have been curated into the platform along with their knowledge. Furthermore, the platform pioneered chat-based knowledge acquisition, standardized machine translation, and collaborative knowledge updating. Together, our study represents the first major advance in leveraging AI to empower NMM knowledge sharing, which not only marks a novel application of AI for Science, but also will significantly benefit the global biomedical, pharmaceutical, physician, and patient communities.

Zijie Yang, Qiji Zhou, Fang Guo et al.

Research data are the foundation of Artificial Intelligence (AI)-driven science, yet current AI applications remain limited to a few fields with readily available, well-structured, digitized datasets. Achieving comprehensive AI empowerment across multiple disciplines is still out of reach. Present-day research data collection is often fragmented, lacking unified standards, inefficiently managed, and difficult to share. Creating a single platform for standardized data digitization needs to overcome the inherent challenge of balancing between universality (supporting the diverse, ever-evolving needs of various disciplines) and standardization (enforcing consistent formats to fully enable AI). No existing platform accommodates both facets. Building a truly multidisciplinary platform requires integrating scientific domain knowledge with sophisticated computing skills. Researchers often lack the computational expertise to design customized and standardized data recording methods, whereas platform developers rarely grasp the intricate needs of multiple scientific domains. These gaps impede research data standardization and hamper AI-driven progress. In this study, we address these challenges by developing Airalogy (https://airalogy.com), the world's first AI- and community-driven platform that balances universality and standardization for digitizing research data across multiple disciplines. Airalogy represents entire research workflows using customizable, standardized data records and offers an advanced AI research copilot for intelligent Q&A, automated data entry, analysis, and research automation. Already deployed in laboratories across all four schools of Westlake University, Airalogy has the potential to accelerate and automate scientific innovation in universities, industry, and the global research community-ultimately benefiting humanity as a whole.

Xinyue Huo, Lingxi Xie, Longhui Wei et al.

Contrastive learning has achieved great success in self-supervised visual representation learning, but existing approaches mostly ignored spatial information which is often crucial for visual representation. This paper presents heterogeneous contrastive learning (HCL), an effective approach that adds spatial information to the encoding stage to alleviate the learning inconsistency between the contrastive objective and strong data augmentation operations. We demonstrate the effectiveness of HCL by showing that (i) it achieves higher accuracy in instance discrimination and (ii) it surpasses existing pre-training methods in a series of downstream tasks while shrinking the pre-training costs by half. More importantly, we show that our approach achieves higher efficiency in visual representations, and thus delivers a key message to inspire the future research of self-supervised visual representation learning.

Xinyue Huo, Lingxi Xie, Jianzhong He et al.

In medical image analysis, semi-supervised learning is an effective method to extract knowledge from a small amount of labeled data and a large amount of unlabeled data. This paper focuses on a popular pipeline known as self learning, and points out a weakness named lazy learning that refers to the difficulty for a model to learn from the pseudo labels generated by itself. To alleviate this issue, we propose ATSO, an asynchronous version of teacher-student optimization. ATSO partitions the unlabeled data into two subsets and alternately uses one subset to fine-tune the model and updates the label on the other subset. We evaluate ATSO on two popular medical image segmentation datasets and show its superior performance in various semi-supervised settings. With slight modification, ATSO transfers well to natural image segmentation for autonomous driving data.