Philippe Thomas

Lisa Raithel, Philippe Thomas, Roland Roller et al.

In this work, we present the first corpus for German Adverse Drug Reaction (ADR) detection in patient-generated content. The data consists of 4,169 binary annotated documents from a German patient forum, where users talk about health issues and get advice from medical doctors. As is common in social media data in this domain, the class labels of the corpus are very imbalanced. This and a high topic imbalance make it a very challenging dataset, since often, the same symptom can have several causes and is not always related to a medication intake. We aim to encourage further multi-lingual efforts in the domain of ADR detection and provide preliminary experiments for binary classification using different methods of zero- and few-shot learning based on a multi-lingual model. When fine-tuning XLM-RoBERTa first on English patient forum data and then on the new German data, we achieve an F1-score of 37.52 for the positive class. We make the dataset and models publicly available for the community.

Lisa Raithel, Hui-Syuan Yeh, Shuntaro Yada et al.

User-generated data sources have gained significance in uncovering Adverse Drug Reactions (ADRs), with an increasing number of discussions occurring in the digital world. However, the existing clinical corpora predominantly revolve around scientific articles in English. This work presents a multilingual corpus of texts concerning ADRs gathered from diverse sources, including patient fora, social media, and clinical reports in German, French, and Japanese. Our corpus contains annotations covering 12 entity types, four attribute types, and 13 relation types. It contributes to the development of real-world multilingual language models for healthcare. We provide statistics to highlight certain challenges associated with the corpus and conduct preliminary experiments resulting in strong baselines for extracting entities and relations between these entities, both within and across languages.

Philippe Thomas, Hind Bril El Haouzi, Marie-Christine Suhner et al.

In recent times, the manufacturing processes are faced with many external or internal (the increase of customized product rescheduling , process reliability,..) changes. Therefore, monitoring and quality management activities for these manufacturing processes are difficult. Thus, the managers need more proactive approaches to deal with this variability. In this study, a proactive quality monitoring and control approach based on classifiers to predict defect occurrences and provide optimal values for factors critical to the quality processes is proposed. In a previous work (Noyel et al. 2013), the classification approach had been used in order to improve the quality of a lacquering process at a company plant; the results obtained are promising, but the accuracy of the classification model used needs to be improved. One way to achieve this is to construct a committee of classifiers (referred to as an ensemble) to obtain a better predictive model than its constituent models. However, the selection of the best classification methods and the construction of the final ensemble still poses a challenging issue. In this study, we focus and analyze the impact of the choice of classifier types on the accuracy of the classifier ensemble; in addition, we explore the effects of the selection criterion and fusion process on the ensemble accuracy as well. Several fusion scenarios were tested and compared based on a real-world case. Our results show that using an ensemble classification leads to an increase in the accuracy of the classifier models. Consequently, the monitoring and control of the considered real-world case can be improved.

Cyrine Selma, Hind Haouzi, Philippe Thomas et al.

In the Canadian's lumber industry, simulators are used to predict the lumbers resulting from the sawing of a log at a given sawmill. Giving a log or several logs' 3D scans as input, simulators perform a real-time job to predict the lumbers. These simulators, however, tend to be slow at processing large volume of wood. We thus explore an alternative approximation techniques based on the Iterative Closest Point (ICP) algorithm to identify the already processed log to which an unseen log resembles the most. The main benefit of the ICP approach is that it can easily handle 3D scans with a variable number of points. We compare this ICP-based nearest neighbor predictor, to predictors built using machine learning algorithms such as the K-nearest-neighbor (kNN) and Random Forest (RF). The implemented ICP-based predictor enabled us to identify key points in using the 3D scans directly for distance calculation. The long-term goal of this ongoing research is to integrated ICP distance calculations and machine learning.

Emmanuel Zimmermann, Hind Haouzi, Philippe Thomas et al.

The purpose of this study is to investigate an approach to group lots in batches and to schedule these batches on Acta-Mobilier cutting work-center while taking into account numerous constraints and objectives. The specific batching method was proposed to handle the Acta-Mobilier problem and a mathematical formalisation and genetic algorithm were proposed to deal with the scheduling problem. The proposed algorithm has been embedded in software to optimise production costs and emphasis the visual management on the production line. The application is currently being used in Acta-Mobilier plant and shows significant results