Takashi Azuma

Hongxiang Lin, Takashi Azuma, Mehmet Burcin Unlu et al.

Photo-Acoustic Tomography (PAT) can reconstruct a distribution of optical absorbers acting as instantaneous sound sources in subcutaneous microvasculature of a human breast. Adjoint methods for PAT, typically Time-Reversal (TR) and Back-Projection (BP), are ways to refocus time-reversed acoustic signals on sources by wave propagation from the position of sensors. TR and BP have different treatments for received signals, but they are equivalent under continuously sampling on a closed circular sensor array in two dimensions. Here, we analyze image quality with discrete under-sampled sensors in the sense of the Shannon sampling theorem. We investigate resolution and contrast of TR and BP, respectively in one source-sensor pair configuration and the frequency domain. With Hankel's asymptotic expansion to the integrands of imaging functions, our main contribution is to demonstrate that TR and BP have better performance on contrast and resolution, respectively. We also show that the integrand of TR includes additional side lobes which degrade axial resolution whereas that of BP conversely has relatively small amplitudes. Moreover, omnidirectional resolution is improved if more sensors are employed to collect the received signals. Nevertheless, for the under-sampled sensors, we propose the Truncated Back-Projection (TBP) method to enhance the contrast of BP using removing higher frequency components in the received signals. We conduct numerical experiments on the two-dimensional projected phantom model extracted from OA-Breast Database. The experiments verify our theories and show that the proposed TBP possesses better omnidirectional resolution as well as contrast compared with TR and BP with under-sampled sensors.

Takumi Noda, Yuu Jinnai, Naoki Tomii et al.

Breast cancer is the most prevalent cancer with a high mortality rate in women over the age of 40. Many studies have shown that the detection of cancer at earlier stages significantly reduces patients' mortality and morbidity rages. Ultrasound computer tomography (USCT) is considered as a promising screening tool for diagnosing early-stage breast cancer as it is cost-effective and produces 3D images without radiation exposure. However, USCT is not a popular choice mainly due to its prolonged imaging time. USCT is time-consuming because it needs to transmit a number of ultrasound waves and record them one by one to acquire a high-quality image. We propose FastUSCT, a method to acquire a high-quality image faster than traditional methods for USCT. FastUSCT consists of three steps. First, it transmits multiple ultrasound waves at the same time to reduce the imaging time. Second, it separates the overlapping waves recorded by the receiving elements into each wave with UNet. Finally, it reconstructs an ultrasound image with a synthetic aperture method using the separated waves. We evaluated FastUSCT on simulation on breast digital phantoms. We trained the UNet on simulation using natural images and transferred the model for the breast digital phantoms. The empirical result shows that FastUSCT significantly improves the quality of the image under the same imaging time to the conventional USCT method, especially when the imaging time is limited.