Suzanne Wendelken

Walid Saba, Suzanne Wendelken, James. Shanahan

Summarization of electronic health records (EHRs) can substantially minimize 'screen time' for both patients as well as medical personnel. In recent years summarization of EHRs have employed machine learning pipelines using state of the art neural models. However, these models have produced less than adequate results that are attributed to the difficulty of obtaining sufficient annotated data for training. Moreover, the requirement to consider the entire content of an EHR in summarization has resulted in poor performance due to the fact that attention mechanisms in modern large language models (LLMs) adds a quadratic complexity in terms of the size of the input. We propose here a method that mitigates these shortcomings by combining semantic search, retrieval augmented generation (RAG) and question-answering using the latest LLMs. In our approach summarization is the extraction of answers to specific questions that are deemed important by subject-matter experts (SMEs). Our approach is quite efficient; requires minimal to no training; does not suffer from the 'hallucination' problem of LLMs; and it ensures diversity, since the summary will not have repeated content but diverse answers to specific questions.

David M. Page, Suzanne M. Wendelken, Tyler S. Davis et al.

Objective: This paper aims to demonstrate functional discriminability among restored hand sensations with different locations, qualities, and intensities that are evoked by microelectrode stimulation of residual afferent fibers in human amputees. Methods: We implanted a Utah Slanted Electrode Array (USEA) in the median and ulnar residual arm nerves of three transradial amputees and delivered stimulation via different electrodes and at different frequencies to produce various locations, qualities, and intensities of sensation on the missing hand. Blind discrimination trials were performed to determine how well subjects could discriminate among these restored sensations. Results: Subjects discriminated among restored sensory percepts with varying cutaneous and proprioceptive locations, qualities, and intensities in blind trials, including discrimination among up to 10 different location-intensity combinations (15/30 successes, p < 0.0005). Variations in the site of stimulation within the nerve, via electrode selection, enabled discrimination among up to 5 locations and qualities (35/35 successes, p < 0.0001). Variations in the stimulation frequency enabled discrimination among 4 different intensities at the same location (13/20 successes, p < 0.005). One subject discriminated among simultaneous, alternating, and isolated stimulation of two different USEA electrodes, as may be desired during multi-sensor closed-loop prosthesis use (20/25 successes, p < 0.001). Conclusion: USEA stimulation enables encoding of a diversity of functionally discriminable sensations with different locations, qualities, and intensities. Significance: These percepts provide a potentially rich source of sensory feedback that may enhance performance and embodiment during multi-sensor, closed-loop prosthesis use.