Zhihao Chen

Zhiyu Ma, Chen Li, Tianming Du et al.

Methods: In this study, a benchmark \emph{Abdominal Adipose Tissue CT Image Dataset} (AATTCT-IDS) containing 300 subjects is prepared and published. AATTCT-IDS publics 13,732 raw CT slices, and the researchers individually annotate the subcutaneous and visceral adipose tissue regions of 3,213 of those slices that have the same slice distance to validate denoising methods, train semantic segmentation models, and study radiomics. For different tasks, this paper compares and analyzes the performance of various methods on AATTCT-IDS by combining the visualization results and evaluation data. Thus, verify the research potential of this data set in the above three types of tasks. Results: In the comparative study of image denoising, algorithms using a smoothing strategy suppress mixed noise at the expense of image details and obtain better evaluation data. Methods such as BM3D preserve the original image structure better, although the evaluation data are slightly lower. The results show significant differences among them. In the comparative study of semantic segmentation of abdominal adipose tissue, the segmentation results of adipose tissue by each model show different structural characteristics. Among them, BiSeNet obtains segmentation results only slightly inferior to U-Net with the shortest training time and effectively separates small and isolated adipose tissue. In addition, the radiomics study based on AATTCT-IDS reveals three adipose distributions in the subject population. Conclusion: AATTCT-IDS contains the ground truth of adipose tissue regions in abdominal CT slices. This open-source dataset can attract researchers to explore the multi-dimensional characteristics of abdominal adipose tissue and thus help physicians and patients in clinical practice. AATCT-IDS is freely published for non-commercial purpose at: \url{https://figshare.com/articles/dataset/AATTCT-IDS/23807256}.

Zhihao Chen, Chuang Niu, Qi Gao et al.

This paper studies 3D low-dose computed tomography (CT) imaging. Although various deep learning methods were developed in this context, typically they focus on 2D images and perform denoising due to low-dose and deblurring for super-resolution separately. Up to date, little work was done for simultaneous in-plane denoising and through-plane deblurring, which is important to obtain high-quality 3D CT images with lower radiation and faster imaging speed. For this task, a straightforward method is to directly train an end-to-end 3D network. However, it demands much more training data and expensive computational costs. Here, we propose to link in-plane and through-plane transformers for simultaneous in-plane denoising and through-plane deblurring, termed as LIT-Former, which can efficiently synergize in-plane and through-plane sub-tasks for 3D CT imaging and enjoy the advantages of both convolution and transformer networks. LIT-Former has two novel designs: efficient multi-head self-attention modules (eMSM) and efficient convolutional feedforward networks (eCFN). First, eMSM integrates in-plane 2D self-attention and through-plane 1D self-attention to efficiently capture global interactions of 3D self-attention, the core unit of transformer networks. Second, eCFN integrates 2D convolution and 1D convolution to extract local information of 3D convolution in the same fashion. As a result, the proposed LIT-Former synergize these two subtasks, significantly reducing the computational complexity as compared to 3D counterparts and enabling rapid convergence. Extensive experimental results on simulated and clinical datasets demonstrate superior performance over state-of-the-art models. The source code is made available at https://github.com/hao1635/LIT-Former.

Zhihao Chen, Qi Gao, Yi Zhang et al.

While various deep learning methods have been proposed for low-dose computed tomography (CT) denoising, most of them leverage the normal-dose CT images as the ground-truth to supervise the denoising process. These methods typically ignore the inherent correlation within a single CT image, especially the anatomical semantics of human tissues, and lack the interpretability on the denoising process. In this paper, we propose a novel Anatomy-aware Supervised CONtrastive learning framework, termed ASCON, which can explore the anatomical semantics for low-dose CT denoising while providing anatomical interpretability. The proposed ASCON consists of two novel designs: an efficient self-attention-based U-Net (ESAU-Net) and a multi-scale anatomical contrastive network (MAC-Net). First, to better capture global-local interactions and adapt to the high-resolution input, an efficient ESAU-Net is introduced by using a channel-wise self-attention mechanism. Second, MAC-Net incorporates a patch-wise non-contrastive module to capture inherent anatomical information and a pixel-wise contrastive module to maintain intrinsic anatomical consistency. Extensive experimental results on two public low-dose CT denoising datasets demonstrate superior performance of ASCON over state-of-the-art models. Remarkably, our ASCON provides anatomical interpretability for low-dose CT denoising for the first time. Source code is available at https://github.com/hao1635/ASCON.

Ke Zou, Zhihao Chen, Xuedong Yuan et al.

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment in real clinical scenes, where patient safety is at stake. Uncertainty estimation plays a pivotal role in producing a confidence evaluation along with the prediction of the deep model. This is particularly important in medical imaging, where the uncertainty in the model's predictions can be used to identify areas of concern or to provide additional information to the clinician. In this paper, we review the various types of uncertainty in deep learning, including aleatoric uncertainty and epistemic uncertainty. We further discuss how they can be estimated in medical imaging. More importantly, we review recent advances in deep learning models that incorporate uncertainty estimation in medical imaging. Finally, we discuss the challenges and future directions in uncertainty estimation in deep learning for medical imaging. We hope this review will ignite further interest in the community and provide researchers with an up-to-date reference regarding applications of uncertainty estimation models in medical imaging.

Tao Chen, Chenhui Wang, Zhihao Chen et al.

Medical image segmentation has been significantly advanced with the rapid development of deep learning (DL) techniques. Existing DL-based segmentation models are typically discriminative; i.e., they aim to learn a mapping from the input image to segmentation masks. However, these discriminative methods neglect the underlying data distribution and intrinsic class characteristics, suffering from unstable feature space. In this work, we propose to complement discriminative segmentation methods with the knowledge of underlying data distribution from generative models. To that end, we propose a novel hybrid diffusion framework for medical image segmentation, termed HiDiff, which can synergize the strengths of existing discriminative segmentation models and new generative diffusion models. HiDiff comprises two key components: discriminative segmentor and diffusion refiner. First, we utilize any conventional trained segmentation models as discriminative segmentor, which can provide a segmentation mask prior for diffusion refiner. Second, we propose a novel binary Bernoulli diffusion model (BBDM) as the diffusion refiner, which can effectively, efficiently, and interactively refine the segmentation mask by modeling the underlying data distribution. Third, we train the segmentor and BBDM in an alternate-collaborative manner to mutually boost each other. Extensive experimental results on abdomen organ, brain tumor, polyps, and retinal vessels segmentation datasets, covering four widely-used modalities, demonstrate the superior performance of HiDiff over existing medical segmentation algorithms, including the state-of-the-art transformer- and diffusion-based ones. In addition, HiDiff excels at segmenting small objects and generalizing to new datasets. Source codes are made available at https://github.com/takimailto/HiDiff.

Zhihao Chen, Yang Zhou, Anh Tran et al.

Medical phrase grounding (MPG) aims to locate the most relevant region in a medical image, given a phrase query describing certain medical findings, which is an important task for medical image analysis and radiological diagnosis. However, existing visual grounding methods rely on general visual features for identifying objects in natural images and are not capable of capturing the subtle and specialized features of medical findings, leading to sub-optimal performance in MPG. In this paper, we propose MedRPG, an end-to-end approach for MPG. MedRPG is built on a lightweight vision-language transformer encoder and directly predicts the box coordinates of mentioned medical findings, which can be trained with limited medical data, making it a valuable tool in medical image analysis. To enable MedRPG to locate nuanced medical findings with better region-phrase correspondences, we further propose Tri-attention Context contrastive alignment (TaCo). TaCo seeks context alignment to pull both the features and attention outputs of relevant region-phrase pairs close together while pushing those of irrelevant regions far away. This ensures that the final box prediction depends more on its finding-specific regions and phrases. Experimental results on three MPG datasets demonstrate that our MedRPG outperforms state-of-the-art visual grounding approaches by a large margin. Additionally, the proposed TaCo strategy is effective in enhancing finding localization ability and reducing spurious region-phrase correlations.

Zhihao Chen, Liang Wan, Yefan Xiao et al.

Shadow removal in a single image has received increasing attention in recent years. However, removing shadows over dynamic scenes remains largely under-explored. In this paper, we propose the first data-driven video shadow removal model, termed PSTNet, by exploiting three essential characteristics of video shadows, i.e., physical property, spatio relation, and temporal coherence. Specifically, a dedicated physical branch was established to conduct local illumination estimation, which is more applicable for scenes with complex lighting and textures, and then enhance the physical features via a mask-guided attention strategy. Then, we develop a progressive aggregation module to enhance the spatio and temporal characteristics of features maps, and effectively integrate the three kinds of features. Furthermore, to tackle the lack of datasets of paired shadow videos, we synthesize a dataset (SVSRD-85) with aid of the popular game GTAV by controlling the switch of the shadow renderer. Experiments against 9 state-of-the-art models, including image shadow removers and image/video restoration methods, show that our method improves the best SOTA in terms of RMSE error for the shadow area by 14.7. In addition, we develop a lightweight model adaptation strategy to make our synthetic-driven model effective in real world scenes. The visual comparison on the public SBU-TimeLapse dataset verifies the generalization ability of our model in real scenes.

Mingya Zhang, Liang Wang, Zhihao Chen et al.

The semantic segmentation task in pathology plays an indispensable role in assisting physicians in determining the condition of tissue lesions. With the proposal of Segment Anything Model (SAM), more and more foundation models have seen rapid development in the field of image segmentation. Recently, SAM2 has garnered widespread attention in both natural image and medical image segmentation. Compared to SAM, it has significantly improved in terms of segmentation accuracy and generalization performance. We compared the foundational models based on SAM and found that their performance in semantic segmentation of pathological images was hardly satisfactory. In this paper, we propose Path-SAM2, which for the first time adapts the SAM2 model to cater to the task of pathological semantic segmentation. We integrate the largest pretrained vision encoder for histopathology (UNI) with the original SAM2 encoder, adding more pathology-based prior knowledge. Additionally, we introduce a learnable Kolmogorov-Arnold Networks (KAN) classification module to replace the manual prompt process. In three adenoma pathological datasets, Path-SAM2 has achieved state-of-the-art performance.This study demonstrates the great potential of adapting SAM2 to pathology image segmentation tasks. We plan to release the code and model weights for this paper at: https://github.com/simzhangbest/SAM2PATH

Mingya Zhang, Zhihao Chen, Yiyuan Ge et al.

In the field of medical image segmentation, models based on both CNN and Transformer have been thoroughly investigated. However, CNNs have limited modeling capabilities for long-range dependencies, making it challenging to exploit the semantic information within images fully. On the other hand, the quadratic computational complexity poses a challenge for Transformers. State Space Models (SSMs), such as Mamba, have been recognized as a promising method. They not only demonstrate superior performance in modeling long-range interactions, but also preserve a linear computational complexity. The hybrid mechanism of SSM (State Space Model) and Transformer, after meticulous design, can enhance its capability for efficient modeling of visual features. Extensive experiments have demonstrated that integrating the self-attention mechanism into the hybrid part behind the layers of Mamba's architecture can greatly improve the modeling capacity to capture long-range spatial dependencies. In this paper, leveraging the hybrid mechanism of SSM, we propose a U-shape architecture model for medical image segmentation, named Hybird Transformer vision Mamba UNet (HTM-UNet). We conduct comprehensive experiments on the ISIC17, ISIC18, CVC-300, CVC-ClinicDB, Kvasir, CVC-ColonDB, ETIS-Larib PolypDB public datasets and ZD-LCI-GIM private dataset. The results indicate that HTM-UNet exhibits competitive performance in medical image segmentation tasks. Our code is available at https://github.com/simzhangbest/HMT-Unet.

Zhihao Chen, Jiahui Wang, Yizhou Chen et al.

PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond, demanding reliable pre-therapy prediction. While LLM-based agents have shown remarkable potential in complex medical diagnosis, their application to PET theranostic outcome prediction remains unexplored, which faces three key challenges: (1) data and knowledge scarcity: RLT was only FDA-approved in 2022, yielding few training cases and insufficient domain knowledge in general LLMs; (2) heterogeneous information integration: robust prediction hinges on structured knowledge extraction from PET/CT, laboratory tests, and free-text clinical documentation; (3) evidence-grounded reasoning: clinical decisions must be anchored in trial evidence rather than LLM hallucinations. In this paper, we present TheraAgent, to our knowledge, the first agentic framework for PET theranostics, with three core innovations: (1) Multi-Expert Feature Extraction with Confidence-Weighted Consensus, where three specialized experts process heterogeneous inputs with uncertainty quantification; (2) Self-Evolving Agentic Memory (SEA-Mem), which learns prognostic patterns from accumulated cases, enabling case-based reasoning from limited data; (3) Evidence-Calibrated Reasoning, integrating a curated theranostics knowledge base to ground predictions in VISION/TheraP trial evidence. Evaluated on 35 real patients and 400 synthetic cases, TheraAgent achieves 75.7% overall accuracy on real patients and 87.0% on synthetic cases, outperforming MDAgents and MedAgent-Pro by over 20%. These results highlight a promising blueprint for trustworthy AI agents in PET theranostics, enabling trial-calibrated, multi-source decision support. Code will be released upon acceptance.

Yi Liu, Zhihao Chen, Yanjun Zhang et al.

Third-party agent skills extend LLM-based agents with instruction files and executable code that run on users' machines. Skills execute with user privileges and are distributed through community registries with minimal vetting, but no ground-truth dataset exists to characterize the resulting threats. We construct the first labeled dataset of malicious agent skills by behaviorally verifying 98,380 skills from two community registries, confirming 157 malicious skills with 632 vulnerabilities. These attacks are not incidental. Malicious skills average 4.03 vulnerabilities across a median of three kill chain phases, and the ecosystem has split into two archetypes: Data Thieves that exfiltrate credentials through supply chain techniques, and Agent Hijackers that subvert agent decision-making through instruction manipulation. A single actor accounts for 54.1\% of confirmed cases through templated brand impersonation. Shadow features, capabilities absent from public documentation, appear in 0\% of basic attacks but 100\% of advanced ones; several skills go further by exploiting the AI platform's own hook system and permission flags. Responsible disclosure led to 93.6\% removal within 30 days. We release the dataset and analysis pipeline to support future work on agent skill security.

Zhihao Chen, Zirui Gong, Jianting Ning et al.

Federated Rank Learning (FRL) is a promising Federated Learning (FL) paradigm designed to be resilient against model poisoning attacks due to its discrete, ranking-based update mechanism. Unlike traditional FL methods that rely on model updates, FRL leverages discrete rankings as a communication parameter between clients and the server. This approach significantly reduces communication costs and limits an adversary's ability to scale or optimize malicious updates in the continuous space, thereby enhancing its robustness. This makes FRL particularly appealing for applications where system security and data privacy are crucial, such as web-based auction and bidding platforms. While FRL substantially reduces the attack surface, we demonstrate that it remains vulnerable to a new class of local model poisoning attack, i.e., fine-grained control attacks. We introduce the Edge Control Attack (ECA), the first fine-grained control attack tailored to ranking-based FL frameworks. Unlike conventional denial-of-service (DoS) attacks that cause conspicuous disruptions, ECA enables an adversary to precisely degrade a competitor's accuracy to any target level while maintaining a normal-looking convergence trajectory, thereby avoiding detection. ECA operates in two stages: (i) identifying and manipulating Ascending and Descending Edges to align the global model with the target model, and (ii) widening the selection boundary gap to stabilize the global model at the target accuracy. Extensive experiments across seven benchmark datasets and nine Byzantine-robust aggregation rules (AGRs) show that ECA achieves fine-grained accuracy control with an average error of only 0.224%, outperforming the baseline by up to 17x. Our findings highlight the need for stronger defenses against advanced poisoning attacks. Our code is available at: https://github.com/Chenzh0205/ECA

Minghong Wei, Pu Cao, Zhihao Chen et al.

With the rapid advancement of intelligent driving and remote sensing, oriented object detection has gained widespread attention. However, achieving high-precision performance is fundamentally constrained by the Angle Boundary Discontinuity (ABD) and Cyclic Ambiguity (CA) problems, which typically cause significant angle fluctuations near periodic boundaries. Although recent studies propose continuous angle coders to alleviate these issues, our theoretical and empirical analyses reveal that state-of-the-art methods still suffer from substantial cyclic errors. We attribute this instability to the structural noise amplification within their non-orthogonal decoding mechanisms. This mathematical vulnerability significantly exacerbates angular deviations, particularly for square-like objects. To resolve this fundamentally, we propose the Fourier Series Coder (FSC), a lightweight plug-and-play component that establishes a continuous, reversible, and mathematically robust angle encoding-decoding paradigm. By rigorously mapping angles onto a minimal orthogonal Fourier basis and explicitly enforcing a geometric manifold constraint, FSC effectively prevents feature modulus collapse. This structurally stabilized representation ensures highly robust phase unwrapping, intrinsically eliminating the need for heuristic truncations while achieving strict boundary continuity and superior noise immunity. Extensive experiments across three large-scale datasets demonstrate that FSC achieves highly competitive overall performance, yielding substantial improvements in high-precision detection. The code will be available at https://github.com/weiminghong/FSC.

Qiaoling Chen, Zhihao Chen, Wei Luo

Effectively classifying remote sensing scenes is still a challenge due to the increasing spatial resolution of remote imaging and large variances between remote sensing images. Existing research has greatly improved the performance of remote sensing scene classification (RSSC). However, these methods are not applicable to cross-domain few-shot problems where target domain is with very limited training samples available and has a different data distribution from source domain. To improve the model's applicability, we propose the feature-wise transformation module (FTM) in this paper. FTM transfers the feature distribution learned on source domain to that of target domain by a very simple affine operation with negligible additional parameters. Moreover, FTM can be effectively learned on target domain in the case of few training data available and is agnostic to specific network structures. Experiments on RSSC and land-cover mapping tasks verified its capability to handle cross-domain few-shot problems. By comparison with directly finetuning, FTM achieves better performance and possesses better transferability and fine-grained discriminability. \textit{Code will be publicly available.}

Zhihao Chen, Tao Chen, Chenhui Wang et al.

While various deep learning methods were proposed for low-dose computed tomography (CT) denoising, they often suffer from over-smoothing, blurring, and lack of explainability. To alleviate these issues, we propose a plug-and-play Language-Engaged Dual-space Alignment loss (LEDA) to optimize low-dose CT denoising models. Our idea is to leverage large language models (LLMs) to align denoised CT and normal dose CT images in both the continuous perceptual space and discrete semantic space, which is the first LLM-based scheme for low-dose CT denoising. LEDA involves two steps: the first is to pretrain an LLM-guided CT autoencoder, which can encode a CT image into continuous high-level features and quantize them into a token space to produce semantic tokens derived from the LLM's vocabulary; and the second is to minimize the discrepancy between the denoised CT images and normal dose CT in terms of both encoded high-level features and quantized token embeddings derived by the LLM-guided CT autoencoder. Extensive experimental results on two public LDCT denoising datasets demonstrate that our LEDA can enhance existing denoising models in terms of quantitative metrics and qualitative evaluation, and also provide explainability through language-level image understanding. Source code is available at https://github.com/hao1635/LEDA.

Zhihao Chen, Yiyuan Ge, Qing Yue

Cloth-changing person re-identification (CC-ReID) aims to retrieve specific pedestrians in a cloth-changing scenario. Its main challenge is to disentangle the clothing-related and clothing-unrelated features. Most existing approaches force the model to learn clothing-unrelated features by changing the color of the clothes. However, due to the lack of ground truth, these methods inevitably introduce noise, which destroys the discriminative features and leads to an uncontrollable disentanglement process. In this paper, we propose a new person re-identification network called features reconstruction disentanglement ReID (FRD-ReID), which can controllably decouple the clothing-unrelated and clothing-related features. Specifically, we first introduce the human parsing mask as the ground truth of the reconstruction process. At the same time, we propose the far away attention (FAA) mechanism and the person contour attention (PCA) mechanism for clothing-unrelated features and pedestrian contour features to improve the feature reconstruction efficiency. In the testing phase, we directly discard the clothing-related features for inference,which leads to a controllable disentanglement process. We conducted extensive experiments on the PRCC, LTCC, and Vc-Clothes datasets and demonstrated that our method outperforms existing state-of-the-art methods.

Zhihao Chen, Yiyuan Ge

Underwater Image Enhancement (UIE) techniques aim to address the problem of underwater image degradation due to light absorption and scattering. In recent years, both Convolution Neural Network (CNN)-based and Transformer-based methods have been widely explored. In addition, combining CNN and Transformer can effectively combine global and local information for enhancement. However, this approach is still affected by the secondary complexity of the Transformer and cannot maximize the performance. Recently, the state-space model (SSM) based architecture Mamba has been proposed, which excels in modeling long distances while maintaining linear complexity. This paper explores the potential of this SSM-based model for UIE from both efficiency and effectiveness perspectives. However, the performance of directly applying Mamba is poor because local fine-grained features, which are crucial for image enhancement, cannot be fully utilized. Specifically, we customize the MambaUIE architecture for efficient UIE. Specifically, we introduce visual state space (VSS) blocks to capture global contextual information at the macro level while mining local information at the micro level. Also, for these two kinds of information, we propose a Dynamic Interaction Block (DIB) and Spatial feed-forward Network (SGFN) for intra-block feature aggregation. MambaUIE is able to efficiently synthesize global and local information and maintains a very small number of parameters with high accuracy. Experiments on UIEB datasets show that our method reduces GFLOPs by 67.4% (2.715G) relative to the SOTA method. To the best of our knowledge, this is the first UIE model constructed based on SSM that breaks the limitation of FLOPs on accuracy in UIE. The official repository of MambaUIE at https://github.com/1024AILab/MambaUIE.

Weichao Pan, Jiaju Kang, Xu Wang et al.

Current road damage detection methods, relying on manual inspections or sensor-mounted vehicles, are inefficient, limited in coverage, and often inaccurate, especially for minor damages, leading to delays and safety hazards. To address these issues and enhance real-time road damage detection using street view image data (SVRDD), we propose DAPONet, a model incorporating three key modules: a dual attention mechanism combining global and local attention, a multi-scale partial over-parameterization module, and an efficient downsampling module. DAPONet achieves a mAP50 of 70.1% on the SVRDD dataset, outperforming YOLOv10n by 10.4%, while reducing parameters to 1.6M and FLOPs to 1.7G, representing reductions of 41% and 80%, respectively. On the MS COCO2017 val dataset, DAPONet achieves an mAP50-95 of 33.4%, 0.8% higher than EfficientDet-D1, with a 74% reduction in both parameters and FLOPs.

Qi Gao, Zhihao Chen, Dong Zeng et al.

The generalization of deep learning-based low-dose computed tomography (CT) reconstruction models to doses unseen in the training data is important and remains challenging. Previous efforts heavily rely on paired data to improve the generalization performance and robustness through collecting either diverse CT data for re-training or a few test data for fine-tuning. Recently, diffusion models have shown promising and generalizable performance in low-dose CT (LDCT) reconstruction, however, they may produce unrealistic structures due to the CT image noise deviating from Gaussian distribution and imprecise prior information from the guidance of noisy LDCT images. In this paper, we propose a noise-inspired diffusion model for generalizable LDCT reconstruction, termed NEED, which tailors diffusion models for noise characteristics of each domain. First, we propose a novel shifted Poisson diffusion model to denoise projection data, which aligns the diffusion process with the noise model in pre-log LDCT projections. Second, we devise a doubly guided diffusion model to refine reconstructed images, which leverages LDCT images and initial reconstructions to more accurately locate prior information and enhance reconstruction fidelity. By cascading these two diffusion models for dual-domain reconstruction, our NEED requires only normal-dose data for training and can be effectively extended to various unseen dose levels during testing via a time step matching strategy. Extensive qualitative, quantitative, and segmentation-based evaluations on two datasets demonstrate that our NEED consistently outperforms state-of-the-art methods in reconstruction and generalization performance. Source code is made available at https://github.com/qgao21/NEED.

Yiyuan Ge, Zhihao Chen, Ziyang Wang et al.

The development of deep learning has facilitated the application of person re-identification (ReID) technology in intelligent security. Visible-infrared person re-identification (VI-ReID) aims to match pedestrians across infrared and visible modality images enabling 24-hour surveillance. Current studies relying on unsupervised modality transformations as well as inefficient embedding constraints to bridge the spectral differences between infrared and visible images, however, limit their potential performance. To tackle the limitations of the above approaches, this paper introduces a simple yet effective Spectral Enhancement and Pseudo-anchor Guidance Network, named SEPG-Net. Specifically, we propose a more homogeneous spectral enhancement scheme based on frequency domain information and greyscale space, which avoids the information loss typically caused by inefficient modality transformations. Further, a Pseudo Anchor-guided Bidirectional Aggregation (PABA) loss is introduced to bridge local modality discrepancies while better preserving discriminative identity embeddings. Experimental results on two public benchmark datasets demonstrate the superior performance of SEPG-Net against other state-of-the-art methods. The code is available at https://github.com/1024AILab/ReID-SEPG.

Zhihao Chen, Yiyuan Ge, Yanyan Lv et al.

The study of Cloth-Changing Person Re-identification (CC-ReID) focuses on retrieving specific pedestrians when their clothing has changed, typically under the assumption that the entire pedestrian images are visible. Pedestrian images in real-world scenarios, however, are often partially obscured by obstacles, presenting a significant challenge to existing CC-ReID systems. In this paper, we introduce a more challenging task termed Occluded Cloth-Changing Person Re-Identification (OC4-ReID), which simultaneously addresses two challenges of clothing changes and occlusion. Concretely, we construct two new datasets, Occ-LTCC and Occ-PRCC, based on original CC-ReID datasets to include random occlusions of key pedestrians components (e.g., head, torso). Moreover, a novel benchmark is proposed for OC4-ReID incorporating a Train-Test Micro Granularity Screening (T2MGS) module to mitigate the influence of occlusion and proposing a Part-Robust Triplet (PRT) loss for partial features learning. Comprehensive experiments on the proposed datasets, as well as on two CC-ReID benchmark datasets demonstrate the superior performance of proposed method against other state-of-the-art methods. The codes and datasets are available at: https://github.com/1024AILab/OC4-ReID.

Zhihao Chen, Tao Chen, Chenhui Wang et al.

Low-dose computed tomography (LDCT) reduces radiation exposure but often degrades image quality, potentially compromising diagnostic accuracy. Existing deep learning-based denoising methods focus primarily on pixel-level mappings, overlooking the potential benefits of high-level semantic guidance. Recent advances in vision-language models (VLMs) suggest that language can serve as a powerful tool for capturing structured semantic information, offering new opportunities to improve LDCT reconstruction. In this paper, we introduce LangMamba, a Language-driven Mamba framework for LDCT denoising that leverages VLM-derived representations to enhance supervision from normal-dose CT (NDCT). LangMamba follows a two-stage learning strategy. First, we pre-train a Language-guided AutoEncoder (LangAE) that leverages frozen VLMs to map NDCT images into a semantic space enriched with anatomical information. Second, we synergize LangAE with two key components to guide LDCT denoising: Semantic-Enhanced Efficient Denoiser (SEED), which enhances NDCT-relevant local semantic while capturing global features with efficient Mamba mechanism, and Language-engaged Dual-space Alignment (LangDA) Loss, which ensures that denoised images align with NDCT in both perceptual and semantic spaces. Extensive experiments on two public datasets demonstrate that LangMamba outperforms conventional state-of-the-art methods, significantly improving detail preservation and visual fidelity. Remarkably, LangAE exhibits strong generalizability to unseen datasets, thereby reducing training costs. Furthermore, LangDA loss improves explainability by integrating language-guided insights into image reconstruction and offers a plug-and-play fashion. Our findings shed new light on the potential of language as a supervisory signal to advance LDCT denoising. The code is publicly available on https://github.com/hao1635/LangMamba.

Zhihao Chen, Qi Gao, Zilong Li et al.

Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despite significant advancements driven by deep learning (DL) in recent years, existing DL-based methods, typically trained on a specific dose level and anatomical region, struggle to handle diverse noise characteristics and anatomical heterogeneity during varied scanning conditions, limiting their generalizability and robustness in clinical scenarios. In this paper, we propose FoundDiff, a foundational diffusion model for unified and generalizable LDCT denoising across various dose levels and anatomical regions. FoundDiff employs a two-stage strategy: (i) dose-anatomy perception and (ii) adaptive denoising. First, we develop a dose- and anatomy-aware contrastive language image pre-training model (DA-CLIP) to achieve robust dose and anatomy perception by leveraging specialized contrastive learning strategies to learn continuous representations that quantify ordinal dose variations and identify salient anatomical regions. Second, we design a dose- and anatomy-aware diffusion model (DA-Diff) to perform adaptive and generalizable denoising by synergistically integrating the learned dose and anatomy embeddings from DACLIP into diffusion process via a novel dose and anatomy conditional block (DACB) based on Mamba. Extensive experiments on two public LDCT datasets encompassing eight dose levels and three anatomical regions demonstrate superior denoising performance of FoundDiff over existing state-of-the-art methods and the remarkable generalization to unseen dose levels. The codes and models are available at https://github.com/hao1635/FoundDiff.

Enbo Zhao, Yi Shen, Shuming Shi et al.

Recently, there is a high demand for deploying DeepSeek-R1 and V3 locally, possibly because the official service often suffers from being busy and some organizations have data privacy concerns. While single-machine deployment offers infrastructure simplicity, the models' 671B FP8 parameter configuration exceeds the practical memory limits of a standard 8-GPU machine. Quantization is a widely used technique that helps reduce model memory consumption. However, it is unclear what the performance of DeepSeek-R1 and V3 will be after being quantized. This technical report presents the first quantitative evaluation of multi-bitwidth quantization across the complete DeepSeek model spectrum. Key findings reveal that 4-bit quantization maintains little performance degradation versus FP8 while enabling single-machine deployment on standard NVIDIA GPU devices. We further propose DQ3_K_M, a dynamic 3-bit quantization method that significantly outperforms traditional Q3_K_M variant on various benchmarks, which is also comparable with 4-bit quantization (Q4_K_M) approach in most tasks. Moreover, DQ3_K_M supports single-machine deployment configurations for both NVIDIA H100/A100 and Huawei 910B. Our implementation of DQ3\_K\_M is released at https://github.com/UnicomAI/DeepSeek-Eval, containing optimized 3-bit quantized variants of both DeepSeek-R1 and DeepSeek-V3.

Shun Zou, Yi Zou, Mingya Zhang et al.

In recent years, Transformer has witnessed significant progress in food recognition. However, most existing approaches still face two critical challenges in lightweight food recognition: (1) the quadratic complexity and redundant feature representation from interactions with irrelevant tokens; (2) static feature recognition and single-scale representation, which overlook the unstructured, non-fixed nature of food images and the need for multi-scale features. To address these, we propose an adaptive and efficient sparse Transformer architecture (Fraesormer) with two core designs: Adaptive Top-k Sparse Partial Attention (ATK-SPA) and Hierarchical Scale-Sensitive Feature Gating Network (HSSFGN). ATK-SPA uses a learnable Gated Dynamic Top-K Operator (GDTKO) to retain critical attention scores, filtering low query-key matches that hinder feature aggregation. It also introduces a partial channel mechanism to reduce redundancy and promote expert information flow, enabling local-global collaborative modeling. HSSFGN employs gating mechanism to achieve multi-scale feature representation, enhancing contextual semantic information. Extensive experiments show that Fraesormer outperforms state-of-the-art methods. code is available at https://zs1314.github.io/Fraesormer.

Junwei Gong, Xiao Shen, Zhihao Chen et al.

Open-set node classification (OSNC) allows unlabeled test data to contain novel classes previously unseen in the labeled data. The goal is to classify in-distribution (ID) nodes into corresponding known classes and reject out-of-distribution (OOD) nodes as unknown class. Despite recent notable progress in OSNC, two challenges remain less explored, i.e., how to enhance generalization to OOD nodes, and promote intra-class compactness and inter-class separability. To tackle such challenges, we propose a novel Negative Mixup with Cross-Layer Graph Contrastive Learning (negMIX) model. Firstly, we devise a novel negative Mixup method purposefully crafted for the open-set scenario with theoretical justification, to enhance the model's generalization to OOD nodes and yield clearer ID/OOD boundary. Additionally, a unique cross-layer graph contrastive learning module is developed to maximize the prototypical mutual information between the same class nodes across different topological distance neighborhoods, thereby facilitating intra-class compactness and inter-class separability. Extensive experiments validate significant outperformance of the proposed negMIX over state-of-the-art methods in various scenarios and settings.

Zhihao Chen, Bin Hu, Chuang Niu et al.

Large language models (LLMs), such as ChatGPT, have demonstrated impressive capabilities in various tasks and attracted an increasing interest as a natural language interface across many domains. Recently, large vision-language models (VLMs) like BLIP-2 and GPT-4 have been intensively investigated, which learn rich vision-language correlation from image-text pairs. However, despite these developments, the application of LLMs and VLMs in image quality assessment (IQA), particularly in medical imaging, remains to be explored, which is valuable for objective performance evaluation and potential supplement or even replacement of radiologists' opinions. To this end, this paper introduces IQAGPT, an innovative image quality assessment system integrating an image quality captioning VLM with ChatGPT for generating quality scores and textual reports. First, we build a CT-IQA dataset for training and evaluation, comprising 1,000 CT slices with diverse quality levels professionally annotated. To better leverage the capabilities of LLMs, we convert annotated quality scores into semantically rich text descriptions using a prompt template. Second, we fine-tune the image quality captioning VLM on the CT-IQA dataset to generate quality descriptions. The captioning model fuses the image and text features through cross-modal attention. Third, based on the quality descriptions, users can talk with ChatGPT to rate image quality scores or produce a radiological quality report. Our preliminary results demonstrate the feasibility of assessing image quality with large models. Remarkably, our IQAGPT outperforms GPT-4 and CLIP-IQA, as well as the multi-task classification and regression models that solely rely on images.

Dongsheng Hong, Chao Chen, Yanhui Chen et al.

Explanation-guided learning (EGL) has shown promise in aligning model predictions with interpretable reasoning, particularly in computer vision tasks. However, most approaches rely on external annotations or heuristic-based segmentation to supervise model explanations, which can be noisy, imprecise and difficult to scale. In this work, we provide both empirical and theoretical evidence that low-quality supervision signals can degrade model performance rather than improve it. In response, we propose ALIGN, a novel framework that jointly trains a classifier and a masker in an iterative manner. The masker learns to produce soft, task-relevant masks that highlight informative regions, while the classifier is optimized for both prediction accuracy and alignment between its saliency maps and the learned masks. By leveraging high-quality masks as guidance, ALIGN improves both interpretability and generalizability, showing its superiority across various settings. Experiments on the two domain generalization benchmarks, VLCS and Terra Incognita, show that ALIGN consistently outperforms six strong baselines in both in-distribution and out-of-distribution settings. Besides, ALIGN also yields superior explanation quality concerning sufficiency and comprehensiveness, highlighting its effectiveness in producing accurate and interpretable models.

Zhou Yang, Zhaochun Ren, Yufeng Wang et al.

Empathetic response generation aims to generate empathetic responses by understanding the speaker's emotional feelings from the language of dialogue. Recent methods capture emotional words in the language of communicators and construct them as static vectors to perceive nuanced emotions. However, linguistic research has shown that emotional words in language are dynamic and have correlations with other grammar semantic roles, i.e., words with semantic meanings, in grammar. Previous methods overlook these two characteristics, which easily lead to misunderstandings of emotions and neglect of key semantics. To address this issue, we propose a dynamical Emotion-Semantic Correlation Model (ESCM) for empathetic dialogue generation tasks. ESCM constructs dynamic emotion-semantic vectors through the interaction of context and emotions. We introduce dependency trees to reflect the correlations between emotions and semantics. Based on dynamic emotion-semantic vectors and dependency trees, we propose a dynamic correlation graph convolutional network to guide the model in learning context meanings in dialogue and generating empathetic responses. Experimental results on the EMPATHETIC-DIALOGUES dataset show that ESCM understands semantics and emotions more accurately and expresses fluent and informative empathetic responses. Our analysis results also indicate that the correlations between emotions and semantics are frequently used in dialogues, which is of great significance for empathetic perception and expression.

Zhihao Chen, Ying Zhang, Yi Liu et al.

Third-party skills extend LLM agents with powerful capabilities but often handle sensitive credentials in privileged environments, making leakage risks poorly understood. We present the first large-scale empirical study of this problem, analyzing 17,022 skills (sampled from 170,226 on SkillsMP) using static analysis, sandbox testing, and manual inspection. We identify 520 vulnerable skills with 1,708 issues and derive a taxonomy of 10 leakage patterns (4 accidental and 6 adversarial). We find that (1) leakage is fundamentally cross-modal: 76.3% require joint analysis of code and natural language, while 3.1% arise purely from prompt injection; (2) debug logging is the primary vector, with print and console.log causing 73.5% of leaks due to stdout exposure to LLMs; and (3) leaked credentials are both exploitable (89.6% without privileges) and persistent, as forks retain secrets even after upstream fixes. After disclosure, all malicious skills were removed and 91.6% of hardcoded credentials were fixed. We release our dataset, taxonomy, and detection pipeline to support future research.

Chenhui Wang, Tao Chen, Zhihao Chen et al.

Despite their impressive generative performance, latent diffusion model-based virtual try-on (VTON) methods lack faithfulness to crucial details of the clothes, such as style, pattern, and text. To alleviate these issues caused by the diffusion stochastic nature and latent supervision, we propose a novel Faithful Latent Diffusion Model for VTON, termed FLDM-VTON. FLDM-VTON improves the conventional latent diffusion process in three major aspects. First, we propose incorporating warped clothes as both the starting point and local condition, supplying the model with faithful clothes priors. Second, we introduce a novel clothes flattening network to constrain generated try-on images, providing clothes-consistent faithful supervision. Third, we devise a clothes-posterior sampling for faithful inference, further enhancing the model performance over conventional clothes-agnostic Gaussian sampling. Extensive experimental results on the benchmark VITON-HD and Dress Code datasets demonstrate that our FLDM-VTON outperforms state-of-the-art baselines and is able to generate photo-realistic try-on images with faithful clothing details.

Zhihao Chen, Yiyuan Ge

The goal of occluded person re-identification (ReID) is to retrieve specific pedestrians in occluded situations. However, occluded person ReID still suffers from background clutter and low-quality local feature representations, which limits model performance. In our research, we introduce a new framework called PAB-ReID, which is a novel ReID model incorporating part-attention mechanisms to tackle the aforementioned issues effectively. Firstly, we introduce the human parsing label to guide the generation of more accurate human part attention maps. In addition, we propose a fine-grained feature focuser for generating fine-grained human local feature representations while suppressing background interference. Moreover, We also design a part triplet loss to supervise the learning of human local features, which optimizes intra/inter-class distance. We conducted extensive experiments on specialized occlusion and regular ReID datasets, showcasing that our approach outperforms the existing state-of-the-art methods.

Ke Zou, Yang Bai, Bo Liu et al.

Medical phrase grounding is crucial for identifying relevant regions in medical images based on phrase queries, facilitating accurate image analysis and diagnosis. However, current methods rely on manual extraction of key phrases from medical reports, reducing efficiency and increasing the workload for clinicians. Additionally, the lack of model confidence estimation limits clinical trust and usability. In this paper, we introduce a novel task called Medical Report Grounding (MRG), which aims to directly identify diagnostic phrases and their corresponding grounding boxes from medical reports in an end-to-end manner. To address this challenge, we propose uMedGround, a robust and reliable framework that leverages a multimodal large language model to predict diagnostic phrases by embedding a unique token, <BOX>, into the vocabulary to enhance detection capabilities. A vision encoder-decoder processes the embedded token and input image to generate grounding boxes. Critically, uMedGround incorporates an uncertainty-aware prediction model, significantly improving the robustness and reliability of grounding predictions. Experimental results demonstrate that uMedGround outperforms state-of-the-art medical phrase grounding methods and fine-tuned large visual-language models, validating its effectiveness and reliability. This study represents a pioneering exploration of the MRG task, marking the first-ever endeavor in this domain. Additionally, we demonstrate the applicability of uMedGround in medical visual question answering and class-based localization tasks, where it highlights visual evidence aligned with key diagnostic phrases, supporting clinicians in interpreting various types of textual inputs, including free-text reports, visual question answering queries, and class labels.

Junting Zhao, Yang Zhou, Zhihao Chen et al.

Automated radiology reporting holds immense clinical potential in alleviating the burdensome workload of radiologists and mitigating diagnostic bias. Recently, retrieval-based report generation methods have garnered increasing attention due to their inherent advantages in terms of the quality and consistency of generated reports. However, due to the long-tail distribution of the training data, these models tend to learn frequently occurring sentences and topics, overlooking the rare topics. Regrettably, in many cases, the descriptions of rare topics often indicate critical findings that should be mentioned in the report. To address this problem, we introduce a Topicwise Separable Sentence Retrieval (Teaser) for medical report generation. To ensure comprehensive learning of both common and rare topics, we categorize queries into common and rare types to learn differentiated topics, and then propose Topic Contrastive Loss to effectively align topics and queries in the latent space. Moreover, we integrate an Abstractor module following the extraction of visual features, which aids the topic decoder in gaining a deeper understanding of the visual observational intent. Experiments on the MIMIC-CXR and IU X-ray datasets demonstrate that Teaser surpasses state-of-the-art models, while also validating its capability to effectively represent rare topics and establish more dependable correspondences between queries and topics.

Tao Chen, Chenhui Wang, Zhihao Chen et al.

While deep learning has significantly advanced medical image segmentation, most existing methods still struggle with handling complex anatomical regions. Cascaded or deep supervision-based approaches attempt to address this challenge through multi-scale feature learning but fail to establish sufficient inter-scale dependencies, as each scale relies solely on the features of the immediate predecessor. To this end, we propose the AutoRegressive Segmentation framework via next-scale mask prediction, termed AR-Seg, which progressively predicts the next-scale mask by explicitly modeling dependencies across all previous scales within a unified architecture. AR-Seg introduces three innovations: (1) a multi-scale mask autoencoder that quantizes the mask into multi-scale token maps to capture hierarchical anatomical structures, (2) a next-scale autoregressive mechanism that progressively predicts next-scale masks to enable sufficient inter-scale dependencies, and (3) a consensus-aggregation strategy that combines multiple sampled results to generate a more accurate mask, further improving segmentation robustness. Extensive experimental results on two benchmark datasets with different modalities demonstrate that AR-Seg outperforms state-of-the-art methods while explicitly visualizing the intermediate coarse-to-fine segmentation process.

Zhihao Chen, Yiyuan Ge, Ziyang Wang

Diffusion-based visuomotor policies excel at modeling action distributions but are inference-inefficient, since recursively denoising from noise to policy requires many steps and heavy UNet backbones, which hinders deployment on resource-constrained robots. Flow matching alleviates the sampling burden by learning a one-step vector field, yet prior implementations still inherit large UNet-style architectures. In this work, we present KAN-We-Flow, a flow-matching policy that draws on recent advances in Receptance Weighted Key Value (RWKV) and Kolmogorov-Arnold Networks (KAN) from vision to build a lightweight and highly expressive backbone for 3D manipulation. Concretely, we introduce an RWKV-KAN block: an RWKV first performs efficient time/channel mixing to propagate task context, and a subsequent GroupKAN layer applies learnable spline-based, groupwise functional mappings to perform feature-wise nonlinear calibration of the action mapping on RWKV outputs. Moreover, we introduce an Action Consistency Regularization (ACR), a lightweight auxiliary loss that enforces alignment between predicted action trajectories and expert demonstrations via Euler extrapolation, providing additional supervision to stabilize training and improve policy precision. Without resorting to large UNets, our design reduces parameters by 86.8\%, maintains fast runtime, and achieves state-of-the-art success rates on Adroit, Meta-World, and DexArt benchmarks. Our project page can be viewed in \href{https://zhihaochen-2003.github.io/KAN-We-Flow.github.io/}{\textcolor{red}{link}}

Hongye Zeng, Ke Zou, Zhihao Chen et al.

Handheld ultrasound devices face usage limitations due to user inexperience and cannot benefit from supervised deep learning without extensive expert annotations. Moreover, the models trained on standard ultrasound device data are constrained by training data distribution and perform poorly when directly applied to handheld device data. In this study, we propose the Training-free Image Style Alignment (TISA) framework to align the style of handheld device data to those of standard devices. The proposed TISA can directly infer handheld device images without extra training and is suited for clinical applications. We show that TISA performs better and more stably in medical detection and segmentation tasks for handheld device data. We further validate TISA as the clinical model for automatic measurements of spinal curvature and carotid intima-media thickness. The automatic measurements agree well with manual measurements made by human experts and the measurement errors remain within clinically acceptable ranges. We demonstrate the potential for TISA to facilitate automatic diagnosis on handheld ultrasound devices and expedite their eventual widespread use.

Alain Lalande, Zhihao Chen, Thibaut Pommier et al.

A key factor for assessing the state of the heart after myocardial infarction (MI) is to measure whether the myocardium segment is viable after reperfusion or revascularization therapy. Delayed enhancement-MRI or DE-MRI, which is performed several minutes after injection of the contrast agent, provides high contrast between viable and nonviable myocardium and is therefore a method of choice to evaluate the extent of MI. To automatically assess myocardial status, the results of the EMIDEC challenge that focused on this task are presented in this paper. The challenge's main objectives were twofold. First, to evaluate if deep learning methods can distinguish between normal and pathological cases. Second, to automatically calculate the extent of myocardial infarction. The publicly available database consists of 150 exams divided into 50 cases with normal MRI after injection of a contrast agent and 100 cases with myocardial infarction (and then with a hyperenhanced area on DE-MRI), whatever their inclusion in the cardiac emergency department. Along with MRI, clinical characteristics are also provided. The obtained results issued from several works show that the automatic classification of an exam is a reachable task (the best method providing an accuracy of 0.92), and the automatic segmentation of the myocardium is possible. However, the segmentation of the diseased area needs to be improved, mainly due to the small size of these areas and the lack of contrast with the surrounding structures.

Zhihao Chen, Jie Gao, Weikai Wang et al.

The troposphere is one of the atmospheric layers where most weather phenomena occur. Temperature variations in the troposphere, especially at 500 hPa, a typical level of the middle troposphere, are significant indicators of future weather changes. Numerical weather prediction is effective for temperature prediction, but its computational complexity hinders a timely response. This paper proposes a novel temperature prediction approach in framework ofphysics-informed deep learning. The new model, called PGnet, builds upon a generative neural network with a mask matrix. The mask is designed to distinguish the low-quality predicted regions generated by the first physical stage. The generative neural network takes the mask as prior for the second-stage refined predictions. A mask-loss and a jump pattern strategy are developed to train the generative neural network without accumulating errors during making time-series predictions. Experiments on ERA5 demonstrate that PGnet can generate more refined temperature predictions than the state-of-the-art.

Zhihao Chen, Liang Wan, Lei Zhu et al.

Shadow detection in a single image has received significant research interest in recent years. However, much fewer works have been explored in shadow detection over dynamic scenes. The bottleneck is the lack of a well-established dataset with high-quality annotations for video shadow detection. In this work, we collect a new video shadow detection dataset, which contains 120 videos with 11, 685 frames, covering 60 object categories, varying lengths, and different motion/lighting conditions. All the frames are annotated with a high-quality pixel-level shadow mask. To the best of our knowledge, this is the first learning-oriented dataset for video shadow detection. Furthermore, we develop a new baseline model, named triple-cooperative video shadow detection network (TVSD-Net). It utilizes triple parallel networks in a cooperative manner to learn discriminative representations at intra-video and inter-video levels. Within the network, a dual gated co-attention module is proposed to constrain features from neighboring frames in the same video, while an auxiliary similarity loss is introduced to mine semantic information between different videos. Finally, we conduct a comprehensive study on ViSha, evaluating 12 state-of-the-art models (including single image shadow detectors, video object segmentation, and saliency detection methods). Experiments demonstrate that our model outperforms SOTA competitors.

Qing Guo, Wei Feng, Zhihao Chen et al.

Intuitively, motion blur may hurt the performance of visual object tracking. However, we lack quantitative evaluation of tracker robustness to different levels of motion blur. Meanwhile, while image deblurring methods can produce visually clearer videos for pleasing human eyes, it is unknown whether visual object tracking can benefit from image deblurring or not. In this paper, we address these two problems by constructing a Blurred Video Tracking benchmark, which contains a variety of videos with different levels of motion blurs, as well as ground truth tracking results for evaluating trackers. We extensively evaluate 23 trackers on this benchmark and observe several new interesting results. Specifically, we find that light blur may improve the performance of many trackers, but heavy blur always hurts the tracking performance. We also find that image deblurring may help to improve tracking performance on heavily blurred videos but hurt the performance on lightly blurred videos. According to these observations, we propose a new GAN based scheme to improve the tracker robustness to motion blurs. In this scheme, a finetuned discriminator is used as an adaptive assessor to selectively deblur frames during the tracking process. We use this scheme to successfully improve the accuracy and robustness of 6 trackers.