Cheng Huang

Cheng Huang, Weizheng Xie, Tsengdar Lee et al.

Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for unraveling glaucoma's underlying mechanisms. In this paper, we propose GlaLSTM, a novel concurrent LSTM stream framework for glaucoma detection, leveraging latent biomarker relationships. Unlike traditional CNN-based models that primarily detect glaucoma from images, GlaLSTM provides deeper interpretability, revealing the key contributing factors and enhancing model transparency. This approach not only improves detection accuracy but also empowers clinicians with actionable insights, facilitating more informed decision-making. Experimental evaluations confirm that GlaLSTM surpasses existing state-of-the-art methods, demonstrating its potential for both advanced biomarker analysis and reliable glaucoma detection.

Zhixin Geng, Xu Fan, Xiqiao Lu et al.

Air pollution has emerged as a major public health challenge in megacities. Numerical simulations and single-site machine learning approaches have been widely applied in air quality forecasting tasks. However, these methods face multiple limitations, including high computational costs, low operational efficiency, and limited integration with observational data. With the rapid advancement of artificial intelligence, there is an urgent need to develop a low-cost, efficient air quality forecasting model for smart urban management. An air quality forecasting model, named FuXi-Air, has been constructed in this study based on multimodal data fusion to support high-precision air quality forecasting and operated in typical megacities. The model integrates meteorological forecasts, emission inventories, and pollutant monitoring data under the guidance of air pollution mechanism. By combining an autoregressive prediction framework with a frame interpolation strategy, the model successfully completes 72-hour forecasts for six major air pollutants at an hourly resolution across multiple monitoring sites within 25-30 seconds. In terms of both computational efficiency and forecasting accuracy, it outperforms the mainstream numerical air quality models in operational forecasting work. Ablation experiments concerning key influencing factors show that although meteorological data contribute more to model accuracy than emission inventories do, the integration of multimodal data significantly improves forecasting precision and ensures that reliable predictions are obtained under differing pollution mechanisms across megacities. This study provides both a technical reference and a practical example for applying multimodal data-driven models to air quality forecasting and offers new insights into building hybrid forecasting systems to support air pollution risk warning in smart city management.

Cheng Huang, Xiaoming Huo

Distributed statistical inference has recently attracted enormous attention. Many existing work focuses on the averaging estimator. We propose a one-step approach to enhance a simple-averaging based distributed estimator. We derive the corresponding asymptotic properties of the newly proposed estimator. We find that the proposed one-step estimator enjoys the same asymptotic properties as the centralized estimator. The proposed one-step approach merely requires one additional round of communication in relative to the averaging estimator; so the extra communication burden is insignificant. In finite sample cases, numerical examples show that the proposed estimator outperforms the simple averaging estimator with a large margin in terms of the mean squared errors. A potential application of the one-step approach is that one can use multiple machines to speed up large scale statistical inference with little compromise in the quality of estimators. The proposed method becomes more valuable when data can only be available at distributed machines with limited communication bandwidth.