Weixin Xu

Jun Ma, Yao Zhang, Song Gu et al.

Quantitative organ assessment is an essential step in automated abdominal disease diagnosis and treatment planning. Artificial intelligence (AI) has shown great potential to automatize this process. However, most existing AI algorithms rely on many expert annotations and lack a comprehensive evaluation of accuracy and efficiency in real-world multinational settings. To overcome these limitations, we organized the FLARE 2022 Challenge, the largest abdominal organ analysis challenge to date, to benchmark fast, low-resource, accurate, annotation-efficient, and generalized AI algorithms. We constructed an intercontinental and multinational dataset from more than 50 medical groups, including Computed Tomography (CT) scans with different races, diseases, phases, and manufacturers. We independently validated that a set of AI algorithms achieved a median Dice Similarity Coefficient (DSC) of 90.0\% by using 50 labeled scans and 2000 unlabeled scans, which can significantly reduce annotation requirements. The best-performing algorithms successfully generalized to holdout external validation sets, achieving a median DSC of 89.5\%, 90.9\%, and 88.3\% on North American, European, and Asian cohorts, respectively. They also enabled automatic extraction of key organ biology features, which was labor-intensive with traditional manual measurements. This opens the potential to use unlabeled data to boost performance and alleviate annotation shortages for modern AI models.

Weixin Xu, Ziliang Wang

Medical ultrasound image segmentation presents a formidable challenge in the realm of computer vision. Traditional approaches rely on Convolutional Neural Networks (CNNs) and Transformer-based methods to address the intricacies of medical image segmentation. Nevertheless, inherent limitations persist, as CNN-based methods tend to disregard long-range dependencies, while Transformer-based methods may overlook local contextual information. To address these deficiencies, we propose a novel Feature Aggregation Module (FAM) designed to process two input features from the preceding layer. These features are seamlessly directed into two branches of the Convolution and Cross-Attention Parallel Module (CCAPM) to endow them with different roles in each of the two branches to help establish a strong connection between the two input features. This strategy enables our module to focus concurrently on both long-range dependencies and local contextual information by judiciously merging convolution operations with cross-attention mechanisms. Moreover, by integrating FAM within our proposed Spatial-Channel Regulation Module (SCRM), the ability to discern salient regions and informative features warranting increased attention is enhanced. Furthermore, by incorporating the SCRM into the encoder block of the UNet architecture, we introduce a novel framework dubbed Spatial-Channel Regulation Network (SCRNet). The results of our extensive experiments demonstrate the superiority of SCRNet, which consistently achieves state-of-the-art (SOTA) performance compared to existing methods.