Jintao Meng

Guangxuan Song, Dongmei Fu, Zhongwei Qiu et al.

Uncertainty estimation is crucial in scientific data for machine learning. Current uncertainty estimation methods mainly focus on the model's inherent uncertainty, while neglecting the explicit modeling of noise in the data. Furthermore, noise estimation methods typically rely on temporal or spatial dependencies, which can pose a significant challenge in structured scientific data where such dependencies among samples are often absent. To address these challenges in scientific research, we propose the Taylor-Sensus Network (TSNet). TSNet innovatively uses a Taylor series expansion to model complex, heteroscedastic noise and proposes a deep Taylor block for aware noise distribution. TSNet includes a noise-aware contrastive learning module and a data density perception module for aleatoric and epistemic uncertainty. Additionally, an uncertainty combination operator is used to integrate these uncertainties, and the network is trained using a novel heteroscedastic mean square error loss. TSNet demonstrates superior performance over mainstream and state-of-the-art methods in experiments, highlighting its potential in scientific research and noise resistance. It will be open-source to facilitate the community of "AI for Science".

Sitian Chen, Yusen Li, Yao Chen et al.

Approximate Nearest Neighbor Search (ANNS) is a core primitive in modern AI systems, and graph-based methods currently offer the best accuracy-efficiency trade-off at scale. The workload is fundamentally memory-bound: graph traversal produces frequent, irregular memory accesses that cap CPU throughput at main-memory bandwidth, while GPUs lack the high-bandwidth memory capacity to host billion-scale indexes. Processing-in-Memory (PIM) is a natural candidate, as placing computation next to data unlocks the abundant internal bandwidth that such bandwidth-starved workloads demand. Porting graph-based ANNS to PIM, however, exposes several architectural mismatches: each processing unit has only a small local memory, inter-unit communication is costly, host coordination adds overhead, and in-memory compute units are relatively weak -- limitations that have forced prior PIM-based ANNS designs to fall back on cluster-based indexing, whose recall ceiling is far below that of graph methods. This paper presents an algorithm-architecture co-design that overcomes these obstacles through three components: a compacted index layout that shrinks the PIM-resident memory footprint by 14.5x; an asynchronous pipelined scheduler that keeps the host-to-PIM interconnect saturated; and a multiplication-free distance kernel that loses under 0.08% recall. Across three billion-scale benchmarks, the proposed design achieves up to 20x and 17.1x higher throughput than CPU and GPU baselines, respectively, outperforms prior PIM accelerators by 129x in the high-recall regime, and scales gracefully across multi-node deployments and emerging PIM architecture.

Ruimin Ma, Ruitao Xie, Yanlin Wang et al.

Autism spectrum disorder (ASD) is a highly disabling mental disease that brings significant impairments of social interaction ability to the patients, making early screening and intervention of ASD critical. With the development of the machine learning and neuroimaging technology, extensive research has been conducted on machine classification of ASD based on structural Magnetic Resonance Imaging (s-MRI). However, most studies involve with datasets where participants' age are above 5 and lack interpretability. In this paper, we propose a machine learning method for ASD classification in children with age range from 0.92 to 4.83 years, based on s-MRI features extracted using contrastive variational autoencoder (CVAE). 78 s-MRIs, collected from Shenzhen Children's Hospital, are used for training CVAE, which consists of both ASD-specific feature channel and common shared feature channel. The ASD participants represented by ASD-specific features can be easily discriminated from TC participants represented by the common shared features. In case of degraded predictive accuracy when data size is extremely small, a transfer learning strategy is proposed here as a potential solution. Finally, we conduct neuroanatomical interpretation based on the correlation between s-MRI features extracted from CVAE and surface area of different cortical regions, which discloses potential biomarkers that could help target treatments of ASD in the future.

Xiang Zhou, Hong Shang, Zijian Zhan et al.

Deep unrolled models (DUMs) have become the state of the art for accelerated MRI reconstruction, yet their robustness under domain shift remains a critical barrier to clinical adoption. In this work, we identify coil sensitivity map (CSM) estimation as the primary bottleneck limiting generalization. To address this, we propose UEPS, a novel DUM architecture featuring three key innovations: (i) an Unrolled Expanded (UE) design that eliminates CSM dependency by reconstructing each coil independently; (ii) progressive resolution, which leverages k-space-to-image mapping for efficient coarse-to-fine refinement; and (iii) sparse attention tailored to MRI's 1D undersampling nature. These physics-grounded designs enable simultaneous gains in robustness and computational efficiency. We construct a large-scale zero-shot transfer benchmark comprising 10 out-of-distribution test sets spanning diverse clinical shifts -- anatomy, view, contrast, vendor, field strength, and coil configurations. Extensive experiments demonstrate that UEPS consistently and substantially outperforms existing DUM, end-to-end, diffusion, and untrained methods across all OOD tests, achieving state-of-the-art robustness with low-latency inference suitable for real-time deployment.

Honglin Zhu, Jiaping Cao, Jiang Shao et al.

Peak breaking Matrix Multiplication is a promising technique to improve the performance of DL, especially in LLM training and inference. We present FalconGEMM, a cross-platform framework that automates the deployment, optimization, and selection of Lower-Complexity Matrix Multiplication Algorithms (LCMAs) across diverse hardware. There are three key innovations: (1) a Deployment Module that enables portable execution across various hardware and input configurations through code generation; (2) an Execution Module with Group-Parallel Optimizations that maximizes on-chip data reuse, utilizes parallel resources, and reduces bandwidth overhead; and (3) a Decision Module featuring a lightweight analytical performance model to select the optimal strategy based on matrix shapes and hardware profiles. Extensive evaluation is conducted on LLM workloads across GPU (H20, A100) and CPU (ARM, x86) architectures with multiple data types. FalconGEMM succeeds in delivering peak breaking performance and outperforms GEMM libraries (e.g., cuBLAS, CUTLASS, Intel MKL, etc) by 7.59%-17.85% and LCMA competitors like AlphaTensor by 12.41%-55.61%. Our framework makes the theoretical promise of LCMAs practical for production deployment across the heterogeneous landscape of modern hardware.