Qiaomei Li

Qiaomei Li, Kara L. Gavin, Corrine I. Voils et al.

Obesity is a critical healthcare issue affecting the United States. The least risky treatments available for obesity are behavioral interventions meant to promote diet and exercise. Often these interventions contain a mobile component that allows interventionists to collect participants level data and provide participants with incentives and goals to promote long term behavioral change. Recently, there has been interest in using direct financial incentives to promote behavior change. However, adherence is challenging in these interventions, as each participant will react differently to different incentive structure and amounts, leading researchers to consider personalized interventions. The key challenge for personalization, is that the clinicians do not know a priori how best to administer incentives to participants, and given finite intervention budgets how to disburse costly resources efficiently. In this paper, we consider this challenge of designing personalized weight loss interventions that use direct financial incentives to motivate weight loss while remaining within a budget. We create a machine learning approach that is able to predict how individuals may react to different incentive schedules within the context of a behavioral intervention. We use this predictive model in an adaptive framework that over the course of the intervention computes what incentives to disburse to participants and remain within the study budget. We provide both theoretical guarantees for our modeling and optimization approaches as well as demonstrate their performance in a simulated weight loss study. Our results highlight the cost efficiency and effectiveness of our personalized intervention design for weight loss.

Qiaomei Li, Rachel Cummings, Yonatan Mintz

A key challenge for decision makers when incorporating black box machine learned models into practice is being able to understand the predictions provided by these models. One proposed set of methods is training surrogate explainer models which approximate the more complex model. Explainer methods are generally classified as either local or global, depending on what portion of the data space they are purported to explain. The improved coverage of global explainers usually comes at the expense of explainer fidelity. One way of trading off the advantages of both approaches is to aggregate several local explainers into a single explainer model with improved coverage. However, the problem of aggregating these local explainers is computationally challenging, and existing methods only use heuristics to form these aggregations. In this paper we propose a local explainer aggregation method which selects local explainers using non-convex optimization. In contrast to other heuristic methods, we use an integer optimization framework to combine local explainers into a near-global aggregate explainer. Our framework allows a decision-maker to directly tradeoff coverage and fidelity of the resulting aggregation through the parameters of the optimization problem. We also propose a novel local explainer algorithm based on information filtering. We evaluate our algorithmic framework on two healthcare datasets---the Parkinson's Progression Marker Initiative (PPMI) data set and a geriatric mobility dataset---which is motivated by the anticipated need for explainable precision medicine. Our method outperforms existing local explainer aggregation methods in terms of both fidelity and coverage of classification and improves on fidelity over existing global explainer methods, particularly in multi-class settings where state-of-the-art methods achieve 70% and ours achieves 90%.